A moderate low-carbohydrate diet has been shown to lower average blood sugar levels and increase time spent within the target glucose range without adverse effects. Participants experienced improved glucose control and felt more satisfied with the new diet.
Researchers at Helmholtz Munich have discovered a new relationship between DNA replication timing and cellular plasticity, allowing for the potential reprogramming of cells. The study found that the three-dimensional structure of the genome influences the flexibility of the replication timing program.
A new study has shed light on the convergent evolution of defensive enrollment in arthropods by analyzing 3D-preserved trilobite soft tissues. The fossils, which date back to the Ordovician Period, show that trilobites used a unique mechanism to protect their vulnerable soft tissues with their hard exoskeletons.
A team of scientists has developed a method to synthesize large-area 2D materials with atomic thickness, exposing single facets. These samples exhibit high crystallinity and ordered domain orientation, making them ideal candidates for studying facet-dependent properties.
Researchers at Tokyo Medical and Dental University have developed a novel method to characterize protein-binding interfaces, revealing complex protein geometries. The technique was validated by studying the homophilic interaction between LAMP2A molecules, which form a trimeric structure in mammalian cells.
A digital training program improved the lives of people with dementia in UK care homes, reducing sedative medication and increasing social interactions. The iWHELD programme delivered personalized care and encouraged meaningful connections, even amidst the COVID-19 pandemic.
Several key public health occupations, including disease intervention specialist and program manager, do not have valid SOC matches, creating challenges in researching the workforce. The study's findings highlight the need for standardization to characterize the public health workforce linked to SOC codes.
Researchers discover a previously undetected mechanism in mice that explains how each sensory cell in mammalian noses becomes tailored to detect a specific odor chemical. The study reveals the genetic molecule RNA plays a crucial role in this process, with RNA winnowing down receptor genes to a single winner.
Researchers at USC Dornsife College of Letters, Arts and Science have invented a new technique called CReATiING that simplifies and cost-effectively constructs synthetic chromosomes. The method enables the creation of complex genetic modifications by combining natural DNA segments from yeast.
A Drexel study found that young adults who know about e-cigarette marketing practices are more likely to have attitudes against vaping. The study suggests that teaching Gen-Z about the industry's marketing tactics can help protect them from vaping.
The inability to burp, known as retrograde cricopharyngeus dysfunction (R-CPD), significantly impacts daily life, causing symptoms like abdominal bloating, flatulence, and difficulty vomiting. Participants reported feeling embarrassed, anxious, and depressed due to R-CPD, highlighting the need for increased awareness and identification.
A study found that individuals who enjoy groove rhythm experience improved executive functions after listening to the same rhythm while exercising. Those who felt their bodies 'resonating' with the music showed enhanced prefrontal cortex activation and improved cognitive abilities compared to those who didn't.
A study revealed that natto consumption significantly reduced atherosclerotic lesions in mouse models, altering intestinal microflora and regulating cytokine production. High vitamin K2 natto showed the most significant effect, decreasing pro-inflammatory cytokines while increasing anti-inflammatory IL-10 production.
Researchers found that inhibitory neurons in the entorhinal cortex continue to migrate and build new connections until age two, contributing to neuroplasticity periods and potential susceptibility to Alzheimer's disease.
A study of 25 obese Chinese individuals reveals that intermittent energy restriction (IER) alters the gut microbiome and brain activity, leading to significant weight loss and reductions in obesity-related comorbidities. The changes are coupled over time, suggesting a complex relationship between the gut microbiome and brain.
Researchers analyzed Aqp10s in eight bony vertebrate species to understand the evolutionary timeline of diminished boric acid and urea transportation. The study found that Aqp10.2 in ray-finned fishes restricts urea and boric acid passage, suggesting a loss of solute transport through evolution.
The UMass Amherst team has developed a first-of-its-kind dual-color optoelectronic neural probe, enabling bidirectional control of brain activity in specific cortical layers. This innovation holds promise for advancing our understanding of diseases such as epilepsy and Parkinson's disease.
A new study highlights the wide range of urban exposures during early childhood that can influence growth and development, including air and noise pollution, overcrowding, and limited green space. The first 2000 days of life are a critical period for physical, cognitive, social, and emotional health outcomes.
Research reveals how diabetes disrupts lung immune cell function, leading to severe infections. Tight control of blood sugar levels or small molecule drugs may alleviate this susceptibility.
Researchers have developed a new method for identifying epitopes that promise safe immunization across broad populations, enabling the creation of targeted vaccines. By exploiting epitope overlaps, they were able to integrate significantly more epitopes into their vaccine candidates, covering over 98% of the world population.
Research found that having high cholesterol and blood pressure before age 55 significantly increases the risk of heart disease in later life. The study's results show a lasting impact on cardiovascular health, even if levels are lowered subsequently.
A study found that viewers' perceptions of Facebook users differed from users' self-perceptions, with multimedia views being more accurate than text-only views. The findings highlight the importance of understanding online self-presentation and impression formation.
A new THz detection method has been developed to measure terahertz radiation directly at the plasma source as it is produced. This method uses nonlinear optics to double the frequency of an optical beam in the presence of a THz wave, providing efficient measurement and characterization of the radiation.
The American Institute of Biological Sciences has selected three winners in its 2023 Faces of Biology Photo Contest. The competition aims to communicate the process of scientific research through photography and showcase biological research in various forms and settings.
A Vienna University of Technology team successfully changed the type of magnetism in a single crystal by applying pressure, reducing frustration and increasing temperature of magnetic phase transition. This discovery could lead to novel materials for secure data storage and quantum computers.
Researchers developed a synaptic transistor capable of higher-level thinking and performing associative learning, categorizing data, and retaining information at room temperature. The device operates fast, consumes low energy, and is ideal for real-world applications.
A Stanford University study reveals that ENPP1 is produced by both cancer cells and healthy cells around tumors, with high levels linked to immunotherapy resistance and metastases. Researchers found that targeting ENPP1 could improve patient responses to existing medicines and help clinicians better predict patient outcomes
The number of new dermatologic drug approvals by the FDA increased significantly between 2012 and 2022, with nearly half considered first in class or indication. This surge in approvals was deemed clinically useful or to have high added therapeutic benefit by health technology assessment organizations.
A team of scientists has developed a statistical technique called BridgePRS to enhance disease prediction in people of non-European ancestry, particularly those of African descent. This advancement aims to reduce health care inequities and enable more personalized medical interventions based on genetic information.
In a study, participants in groups that could share information contributed more than those who couldn't. Sharing info about low contributors increased future contributions among exposed players.
Researchers in Chile developed a prototype using microorganisms to remove VOCs and PAHs from indoor air, achieving efficiencies above 90%. The system can operate for 8 months without losing efficiency. This breakthrough offers a potentially low-cost solution to improve indoor air quality.
Researchers at the University of Seville have developed a bioinspired PEM fuel cell design that improves the distribution of liquid water inside these batteries. This approach has the potential to significantly enhance the efficiency and durability of PEM fuel cells, leading to more efficient and sustainable energy systems.
A new study reveals that pandas are more socially active than previously thought, using scent-marking trees to exchange information about their lives. In non-mating seasons, they primarily hang with family members, but branch out during mating seasons.
Researchers have developed a stem cell-derived model of heart tissue that provides insight into tachycardia, a condition where the heart beats out of control. The engineered tissues were used to study how fast heart rates affect the heart and uncover the inner workings of the body's engine.
Scientists have created a self-organizing neuromuscular junction model from human pluripotent stem cells to study complex neuromuscular diseases. The 2D and 3D cultures mimic the physiological situation, allowing researchers to perform high-throughput drug screening for novel treatments.
The grant will enable AU's Office of Research to build institutional capacity for translational research and train graduate students in this field. American University aims to leverage basic research into data-driven decision-making, promoting a culture of research translation on its campus and beyond.
Researchers discovered that humans can differentiate between primate vocalizations based on acoustic similarity to human speech. The study suggests that the human brain processes primate calls more efficiently when they are closer in frequency to human language, not just phylogenetically close.
Research finds that animated short videos are an effective means for disseminating environmental health information to health professionals. The studies showed significant increases in participant knowledge and perceived comfort in identifying at-risk patients impacted by air pollution.
A nationwide cohort study in Japan found that continuing oral anticoagulation therapy after catheter ablation for atrial fibrillation increases the risk of major bleeding but decreases the risk of thromboembolic events. Discontinuing oral anticoagulants in patients with a lower CHADS 2 score may be beneficial.
A new study published in PLOS Medicine found no association between assisted reproductive technologies and body mass index in children, except when using frozen embryos. The study analyzed data from Denmark and other countries, providing insights into the health outcomes of children born through assisted reproductive technologies.
A team from the University of Utah found that snowflakes' accelerations follow an exponential distribution with a consistent exponent, regardless of turbulence or type. This discovery has significant implications for storm forecasting and understanding climate change.
A new study reveals that humans have driven the extinction of 1,430 bird species, with many becoming extinct before written records. The research suggests that major human-driven extinctions occurred in the 14th century and ninth century BC, with ongoing threats including climate change and invasive species.
A team of researchers has decoded the genetic diversity of nine species of wild North American grapes, revealing critical traits that could accelerate grape breeding efforts. The research identifies key genes responsible for important traits such as salt tolerance, drought resistance, and defense against Pierce's disease.
Researchers at Museums Victoria Research Institute uncover evidence that giant baleen whales evolved first in the Southern Hemisphere around 20 million years ago. This finding disrupts previous theories and highlights the importance of the Australian fossil record in shaping our understanding of whale evolution.
A new map showing all above-ground biomass in the Brazilian Amazon has been published, derived from a study combining airborne laser scanning, satellite imagery, and forest inventories. The results show an average of 174 metric tons of biomass per hectare and a maximum of 518 tons per hectare.
A new study suggests that giant pandas are active users of 'social media' in the form of scent-marking trees. The research team analyzed DNA from fresh panda poop to determine which bears were close to each other and used this information to explore their social network. The findings reveal that during non-mating seasons, pandas tend t...
Scientists in Germany developed a new analytical method to precisely elucidate the size of particles, structure, and RNA molecules in pharmaceutical products. This information can help evaluate product quality, enabling improved development of new products.
A research team developed an innovative optical technique, 'spectrum shuttle,' to produce and shape GHz burst pulses. The method facilitates ultrafast imaging within subnanosecond timescales, enabling analysis of rapid phenomena.
Researchers found local rivers and streams to be the source of Salmonella enterica contamination after Hurricane Florence, contradicting assumptions about pig farms. The study has critical implications for disease control and prevention in coastal regions affected by tropical storms.
A recent study published in EBioMedicine found that yellow fever virus causes myocardial fibrosis, cardiomyocyte hypertrophy, and vascular endothelium alterations, leading to cardiac conduction system disruption. The research provides new insights into the pathogenesis of YF-associated heart injury.
A systematic review of 20 empirical studies found that CEO financial incentives have a small predictive effect on return on assets, but no effect on other performance metrics or financial restatements. The analysis suggests caution regarding current practices and recommends alternative arrangements to enhance firm performance.
Researchers found that colon cancer screenings reduce cancer rates by about 0.5 percent, doubling previous estimates of a quarter of a percentage point. This effect is twice the impact of just being invited to screen, suggesting that actual screening rather than just the offer makes a difference.
Researchers Dr. Maisa Rojas and Marco Billi propose a new model of governance to address climate change in Chile, prioritizing social justice and ecological order. This approach aims to mitigate the effects of climate change on vulnerable groups and promote transformative change.
A new study reveals antimicrobial resistance (AMR) is responsible for a staggering 25% of mortality in the WHO African region, with lower respiratory infections emerging as primary causes. The four most prevalent pathogens, Streptococcus pneumoniae and others, are individually linked to over 100,000 deaths.
Researchers at Tokyo Medical and Dental University develop a genome-editing technique that decreases PMP22 protein levels in patient cells, potentially reversing CMT-related changes. The study aims to improve myelination abilities and reduce symptoms in patients with CMT type 1A.
Researchers at Nagoya University used AI to analyze image data of polycrystalline silicon and discovered staircase-like structures that cause dislocations during crystal growth. The study sheds light on the formation of dislocations in polycrystalline materials, which can affect electrical conduction and overall performance.
The new position will focus on quantum information processing, particularly communication and computation. Dr. Nape brings prestigious accolades, including the SAIP Silver Medal and recognition on the Top 200 Young South Africans list.
Two new tarantula species have been discovered in Ecuador's wilderness, but they are already threatened due to habitat destruction and human activities. The implementation of protected areas is essential to conserve these endangered species and prevent further extinction.
A new study published in Neurology found that nearly 30% of caregivers for severe stroke patients experience high levels of anxiety, depression, or post-traumatic stress during the first year after hospital discharge. Post-traumatic stress was particularly common among Mexican American caregivers.
A $2 million three-year grant from the U.S. Department of Commerce will create a regional incubator for life sciences startups in South Carolina, providing them with expertise, resources, and networking opportunities.