Researchers propose DeciLS-PBO, a local search method for pseudo-Boolean optimization, outperforming existing solvers on most instances. The new method uses unit propagation and a heuristic defined on clauses to improve performance.
Researchers propose a novel annotation strategy called Drag&Drop, which enables manual labeling based on a single 2D annotation in high-dimensional volumetric data. The proposed framework achieves a comparable tumor detection rate to per-pixel annotations and higher rates than alternative weak annotation strategies.
A new auxiliary CHD diagnostic system has been developed to identify TTE cardiac views, integrate information from various views and modalities, and predict the probability of a subject being normal or having a heart defect. The system uses a hierarchical network structure and has been shown to accurately detect children with CHD.
The article explores the evolution of resilient cities to bold cities, focusing on policies, actions, and hot trends. Key findings include multi-level governance, circular economy, nature-based solutions, equal opportunities, and open data capabilities.
Researchers at HKUST discovered that phase separation enables controlled movement of synaptic vesicles between different regions of the cell. They identified two key proteins, Piccolo and TFG, involved in this process.
A new study from the University of South Australia shows that young children learn about pain through reading, promoting empathy and emotional development. Reading picture books frequently prompts interactions about pain and injury, teaching valuable responses to these concepts.
Researchers developed Cas9 variants to target non-canonical PAMs in Brassica, expanding genome editing capabilities. The SpRY variant showed high editing efficiency at near-PAM-less sites, enabling precise adenine base editing.
Research suggests that the source of sugar, rather than the amount consumed, is crucial in developing obesity in children. A study found that children who got their sugar from unsweetened dairy products and fruit had a lower risk of becoming overweight or obese.
Researchers discovered that variations in macrophages, ancient immune cells, are linked to patients' recovery and survival in diffuse large B-cell lymphoma. The study found subsets of macrophages associated with relapse after chemotherapy, predicting disease progression and potential new therapeutic approaches.
A genetic variant present in 3-4% of self-identified Black individuals increases the risk for heart failure and death. Carriers of the V142I variant are at significantly increased risk for heart failure beginning in their 60s, with an increased risk for death beginning in their 70s.
New regulations in China significantly reduced daily sedentary time by 13.8% and increased students' likelihood of meeting screen time recommendations. The measures, which restricted online gaming and homework assignments, were found to be effective in improving children's physical and mental wellbeing.
Scientists have discovered six high-redshift galaxies using the FAST telescope, finding significantly more atomic hydrogen gas than previously surveyed galaxies. This reveals that galaxies four billion years ago had more star-forming gas than current-day galaxies, challenging previous assumptions.
Researchers from CSUFT have developed a novel transparent material derived from natural bamboo with three-layered flame-retardant barrier. The material exhibits excellent mechanical properties, high light transmittance, and potential applications in green flame-retardant glass and optical device applications.
The V142I transthyretin variant is associated with substantial risk for heart failure hospitalization and death in Black individuals, particularly those with reduced ejection fraction. Further investigation into the complex interplay between the variant, ancestry, social determinants of health, and biological factors is warranted.
A randomized trial found that aerobic exercise significantly reduced inflammatory markers in adults with obesity, including IL-6 and IFN-γ levels. Exercise combined with liraglutide treatment showed no additional benefits in reducing inflammation compared to placebo or liraglutide alone.
A Danish study found that patients who tapered off semaglutide slowly and focused on lifestyle changes maintained their weight loss for at least 6 months. Lower doses of the drug were as effective as higher ones, with a tailored approach minimising side-effects.
A Europe-wide study found that individuals living with overweight or obesity have a higher probability of being absent from work due to health issues, as well as taking longer sick days. This has significant implications for economies and productivity across the continent.
Researchers found that smokers skip meals more often, go longer without eating, and are more likely to snack between meals. They also tend to eat fewer sweet foods, but more fried foods, salt, and sugar than non-smokers.
The team developed a deep learning AI technique to quantitatively analyze cation mixing using atomic structure images. This approach revealed that introducing metal dopants like aluminum, titanium, and zirconium into the transition metal layer fortified bonds between nickel and oxygen atoms, curbing cation mixing.
Researchers have developed an efficient single pixel imaging scheme using a compact fiber laser array and untrained deep neural network. The system enables rapid speckle projection and reconstructs high-quality images, making it suitable for remote sensing and target detection applications.