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Science News for December 31, 2025


Clinical trials on AI language model use in digestive healthcare

A systematic review of randomized controlled trials evaluating large language models in digestive diseases found only 14 eligible studies worldwide. Most focused on gastrointestinal and hepatobiliary diseases, with clinical decision-making and patient education being common applications. The authors emphasize the need for high-quality ...

SourceKeAi Communications Co., Ltd.·JournalGastroenterology & Endoscopy·TypeLiterature review·DateDec 31, 2025

From addressing uncertainty to national strategy: an interpretation of Professor Lim Siong Guan’s views

Professor Lim Siong Guan shares insights on how to navigate uncertainty in a rapidly changing world by emphasizing the importance of governance, leadership development, and institutional culture. He stresses the need for proactive planning, trust-building, and adaptability in response to unexpected events.

SourceKeAi Communications Co., Ltd.·JournalRisk Sciences·TypeCommentary/editorial·DateDec 31, 2025

Interaction of climate change and human activity and its impact on plant diversity in Qinghai-Tibet plateau

The Qinghai-Tibet plateau faces multiple conservation challenges due to climate change and human activity. Research reveals shifting plant diversity under these pressures, with critical gaps in understanding the mechanisms behind acclimation and adaptation. Future research prioritization is proposed to address conservation concerns.

SourceKeAi Communications Co., Ltd.·JournalPlant Diversity·TypeLiterature review·DateDec 31, 2025

Transfer printing techniques and their applications in photonic integrated circuits

Researchers review transfer printing techniques for integrating III-V semiconductor devices into silicon photonics, enabling diverse optical functionalities and applications. The technology offers precise control over thin film parameters and precise device placement.

Breakthrough in multiculture study of Sanghuang: secondary metabolite diversity reveals significant in vitro antidiabetic potential

Researchers discovered that culture conditions drive the synthesis of secondary metabolites, leading to significant α-glucosidase inhibitory activity. The study identified potential active compounds for anti-diabetes treatment and provided actionable insights for optimizing cultivation processes.

SourceHigher Education Press·JournalSystems Microbiology and Biomanufacturing·TypeExperimental study·DateDec 31, 2025

Engineering thermostable endo-polygalacturonases as a novel tool for efficient functional oligosaccharide production

Researchers created a novel enzyme tool by modifying an existing fungal-derived endo-polygalacturonase, enhancing its thermal stability and catalytic efficiency. The new enzyme efficiently produces pectic oligosaccharides with prebiotic potential, promoting beneficial probiotic growth.

SourceHigher Education Press·JournalSystems Microbiology and Biomanufacturing·TypeExperimental study·DateDec 31, 2025

HKUST researchers unveil chemical blueprint for monolayer altermagnets, discovering 612 altermagnet candidates

The team designed a strategy to create monolayer altermagnets using V2(Se,Te)2O as a template. High-throughput calculations identified 612 potential altermagnets with spin-splitting bands and CSML, showcasing their precision and potential for advanced spintronics applications.

SourceScience China Press·JournalNational Science Review·TypeComputational simulation/modeling·DateDec 31, 2025

Spin textures and multi-periodic spin tunnel junction enable record polarization in semiconductor light emitting

Researchers develop record-high circular polarization of 25.3% in GaN-based spin-LEDs using multi-periodic spin tunnel junction, enabling zero-field spin-LED performance. The design harnesses topological spin textures for controlling electrons and filtering, achieving a breakthrough in device operation.

SourceScience China Press·JournalScience Bulletin·TypeExperimental study·DateDec 31, 2025

Enriching framework Al sites in 8-membered rings of Cu-SSZ-39 zeolite to enhance low-temperature ammonia selective catalytic reduction performance

Researchers developed a potassium-based Cu-SSZ-39 catalyst with increased Al concentration in 8-membered rings, enhancing NOx conversion at low temperatures and retaining activity after hydrothermal ageing. The work presents an effective strategy for tailoring Al distribution in zeolites to improve NH3-SCR performance.