The updated guideline provides recommendations for preventive medications for both chronic and episodic migraine, taking into account new research and medication options. Clinicians are advised to assess the impact of migraine on quality of life when choosing a preventive medication, and to discuss the strength of evidence, possible si...
C.S. Mott Children's Hospital is the first hospital in the US to implant an expandable heart valve, the Autus Valve, during the FDA review phase. The device is designed to grow with children and can potentially reduce the need for replacement surgeries.
Binghamton University professor Stephanie Tulk Jesso is developing cognitive behavioral architecture to enable robots to understand human needs and improve healthcare outcomes. Her research focuses on co-designing AI systems with nurses to reduce errors and enhance patient care.
The Europlanet Science Congress 2026 will cover various topics in planetary research, including the Solar System, exoplanets, and artificial intelligence. The conference will feature over 125 scientific sessions and keynote talks, with around 1200 planetary scientists attending from 40 countries.
The $8 million grant will unite Boise State, University of Idaho, and three community colleges to develop resilient microelectronics for extreme environments. The project aims to create long-term research infrastructure and train students in materials science and engineering.
A nationwide study found that air conditioning usage cut annual heat-related deaths by half in the US, saving over 5,000 lives. Moderate AC usage provides the most benefits, while over-usage may flatten benefits.
A new study reveals that the loss of kelp forests has a significant impact on microbial levels, leading to changes in ecosystem functioning and potentially affecting human services such as nutrient retention and carbon storage. The research highlights the importance of considering the microbial component in understanding ecosystem change.
Researchers developed a method to distinguish authentic ancient clay artifacts from fakes by analyzing the magnetic properties of the clay. By measuring the temperature needed to erase magnetism acquired over time, the method can determine the age and authenticity of the artifact.
Researchers created a 3D platform using human-derived nerve cells and Schwann cells to study nerve cell formation and myelin coating development. The platform enables functional myelin formation and allows for the study of nerve damage and repair, as well as the testing of potential treatments.
A study by Goethe University and Universitätsmedizin Frankfurt has found that seminal fluid can facilitate infection of skin cells with the monkeypox virus. The researchers discovered that protein fragments in seminal fluid form fibers that promote attachment of the virus to human cells, increasing the risk of transmission through sexu...
Scientists have found that short peptides can remain stable and fold into shapes that may give them biological functions in highly acidic conditions similar to Venus's cloud layer. This discovery opens up new possibilities for the search for life on planets that don't resemble Earth.
Researchers developed flexible Te/PET films for ultrafast all-optical terahertz modulators, achieving high modulation depth and ultrasensitive response. The device maintained stable performance under bending deformation, enabling reliable information processing for intelligent sensing and neuromorphic optoelectronic systems.
Researchers have developed a wide-field hyperspectral camera that captures real-time spectral changes from hundreds of nanoparticles simultaneously, revealing hidden heterogeneity in electrodeposition. The technique, called wide-field Fourier transform hyperspectral imaging, solves the throughput bottleneck in conventional dark-field s...
Researchers identify HLA-E as a key regulator of metastasis-initiating hepatocyte states, linked to IFN-γ–JAK–STAT3 pathway. Chronic immune pressure contributes to metastasis initiation in HCC, suggesting a new target for limiting immune-driven metastasis.
Overfermentation of cocoa beans can cause smoky, leathery, and cheesy off-flavors, with elevated concentrations of short-chain carboxylic acids and phenols detected. A simple measurement using test strips can help detect the onset of overfermentation, preventing the development of off-flavors.
Researchers investigated NDUFA11's role in Parkinson's disease, finding it maintains mitochondrial function and integrity. Impaired NDUFA11 function contributes to mitochondrial dysfunction, oxidative stress, and PD-related abnormalities.
Researchers discovered a new kind of planar defect, called 'filling fault,' in half-Heusler compounds. This defect arises from the local filling of vacant sublattices and introduces stoichiometric deviations, affecting material properties.
Researchers discovered plant bundles from the Wuwangdun Tomb, containing rice, millets, and other cereals, wrapped in oak leaves, with similar structures to modern zongzi. The bundles were likely used as funerary offerings, distinguishing them from their modern counterparts.
Research discovered calcium-binding protein CSE in multicellular cyanobacteria, regulating cell-to-cell communication and forming tissue-like structures. This finding suggests that functional principles of higher organisms existed in simple bacteria a billion years ago.
A clinical trial has demonstrated a new treatment that reduces bleeding within the heart muscle and preserves heart function in severe heart attack patients. The trial tested a peri-reperfusion therapy that limits hemorrhagic myocardial injury after primary percutaneous coronary intervention.
High-risk patients taking evolocumab had a 20% lower risk of death compared to those on placebo, according to a Mass General Brigham study. The study found that intensive LDL-C lowering with evolocumab was associated with lower risk of heart attack and stroke, as well as improved survival in high-risk patients without a prior CV event.
Tumor-infiltrating lymphocyte therapy has shown potential in several types of solid tumors, including metastatic melanoma, breast cancer, and ovarian cancer. Despite challenges, the approach has favorable clinical outcomes, and researchers are exploring combination strategies and advanced technologies to improve treatment durability.
Transient intestinal inflammation can leave irreversible changes in the gut lining, leading to Crohn's disease and ulcerative colitis. Long-term inflammation rewires intestinal stem cells, preventing normal regeneration and creating chronic disease.
The Lancet Haematology series examines how clinicians can better identify and track treatment effects on patients during and after blood cancer treatment. Digital tools, such as symptom-reporting apps and artificial intelligence, could support changes in care, but must be accurate and equitable.
Researchers at MSK have identified a protein called integrin alpha-5 as a key driver of lung metastasis across several cancer types. A new three-drug combination that includes epcoritamab, rituximab, and lenalidomide is effective in almost all patients newly diagnosed with follicular lymphoma, offering a potential alternative to chemot...
The Atrax sounding rocket test has provided significant reentry vibration data that will help improve modeling and simulation tools for the W93 warhead. This data will enable scientists and engineers to design nonnuclear components more precisely, reducing risk and improving the overall survivability of the system.
Scientists have identified a microbiome signaling system that controls intestinal movement, revealing a potential new direction for treating constipation-predominant irritable bowel syndrome. The discovery points to restoring combinations of microbial signals to restore normal function.
Higher TMAO concentrations were associated with older age, cardiometabolic risk factors, and brain atrophy, but not cognitive performance. The study suggests TMAO may be a marker of systemic aging processes rather than a direct mediator of neurodegeneration.
Researchers investigate how consumers incorporate dollar stores into their household food purchases and explore health concerns surrounding the proliferation of dollar stores. The study aims to develop educational resources and tools to help consumers stretch their food budget and maintain a nutritious diet utilizing dollar stores.
A new AI method called neural posterior estimation (NPE) uses genetic sequences to analyze the evolution of infectious diseases. This allows for real-time management of epidemics and epizootics, with the ability to add new data at any time.
Researchers aim to identify biological differences among patients to guide treatment with precision therapeutics and computational approaches. The goal is to improve treatment outcomes for schizophrenia, a condition that affects perception of reality.
Researchers have discovered an epigenetic mechanism that allows a rare tree species to track its age and trigger flowering. The study found that a decline in DNA methylation levels directly activates reproductive genes, enabling the tree to transition from vegetative growth to flowering.
The Workshop on Public Health Policy, Risk Perception, and Infectious Disease successfully bridged the gap between epidemiological modeling and policy implementation for infectious diseases. Participants discussed practical challenges and mutual benefits of using models to support public health decision-making.
A new study examining 39,761 students in Ontario school boards found that 1 in 5 students used AI for emotional needs, with those who did being more likely to struggle with serious emotional problems and feel isolated. The study urges parents, educators, and clinicians to pay attention to why young people turn to chatbots.
A new kinetic model reconciles field observations and laboratory experiments, showing that temperature dependence and multiphase kinetics resolve observed growth rates. The model considers reactivity, diffusivity, and concentration gradients of chemical species across gas and condensed phases.
Dr. Emily Flanagan's five-year NIH grant will investigate how energy intake and expenditure influence infant growth and future obesity risk. The study aims to improve energy-intake standards for infants and identify critical periods for interventions promoting healthy growth.
Researchers found lead levels were 7 times higher near airports compared to other areas of Portland, with aviation fuel as the dominant source. The study highlights the need for soil testing to address lead exposure risks for children.
A recent study from the Dog Aging Project found that dogs with five or more chronic diseases were more than twice as likely to die as dogs living with only one diagnosed condition. Chronic diseases can dramatically shorten a dog's lifespan, highlighting the importance of managing multiple diseases together rather than individually.
The American Academy of Neurology has launched BrainHealth.com, a public resource providing expert-reviewed information, tools, and stories to improve brain health. The website offers trustworthy guidance, practical resources, and personal stories to help people navigate brain health with confidence.
A new study from the University of California San Diego reveals that the brain tracks subtle variations in breathing to decode neural activity patterns. Researchers found a precise connection between breathing patterns and brain activity, offering new avenues for understanding disorders like SUDEP and SIDS.
Research reveals individual breaths at rest create unique brain wave patterns, affecting mental processes such as thinking, attention, and emotional regulation. The study suggests that brain-body interactions are crucial for assessing and treating neuropsychiatric patient populations.
Researchers developed tools to compare tumor microenvironments and predict treatment response by analyzing spatial transcriptomic data. The new tools provide a detailed map of tumor cell organization, enabling clinicians to quickly analyze and compare tumor 'floor plans' and determine the best course of treatment.
Researchers propose framework for closed-loop haptic interaction in VR/AR, linking tactile sensing, intelligent processing, and physical feedback. The review identifies flexible electronic skins and four research priorities to close the haptic interaction gap.
Researchers developed a compact built-in prompt gamma-ray neutron activation analysis (PGNAA) system to measure uranium loading and ionic contaminants in hydrometallurgy processes. The system provides on-site trends to support decisions on resin switching and elution timing.
Researchers have discovered a mechanism that could help develop disease-resistant plant varieties with high yield potential. Steroid hormones regulate a molecular switch controlling the immune response, allowing plants to prioritize growth over defense against pathogens.
A study by Aalto University reveals pro-Russian hackers are using 'gamified' DDoS attacks to undermine public trust in governments and institutions, with cryptocurrency-based rewards for successful attacks. The researchers urge companies and governments to counteract the effects of propaganda and psychological intimidation.
A team of researchers has discovered four sets of dual 'Little Red Dots' (LRDs) in the early universe, indicating a possible link between galaxy mergers and rapidly growing black holes. The findings suggest that black hole mergers could be responsible for the rapid growth of black holes in the early universe.
A recent study found that TYW5 gene dysregulation is associated with circadian disruption and schizophrenia, affecting locomotor rhythms and prefrontal synaptic ultrastructure. Altering TYW5 expression levels in mice led to changes in behavior, including increased locomotor activity and anxiety-like behavior.
PTHrP inhibits BMP2-induced osteochondral differentiation by inactivating the PI3K–AKT signaling pathway, preserving cartilage phenotype and promoting chondrogenesis. This finding suggests PTHrP's potential application in BMP2-based cartilage tissue engineering.
Researchers propose that wave function phase is the source of randomness in quantum mechanics, potentially leading to new AI advancements. This idea contradicts current understanding and warrants experimental verification.
A recent study published in Cell Death & Differentiation highlights the role of endoplasmic reticulum stress proteins in osteoarthritis, revealing their contribution to inflammation and tissue remodeling. The research identifies a promising protein, PDIA4, which may serve as a therapeutic target for limiting disease progression.
The EU-funded projects SpongeBoost, SpongeScapes, and SpongeWorks have published a joint policy brief recommending aligning EU policies to scale up sponge restoration across Europe. The policy brief highlights the importance of restoring the natural sponge function of landscapes to strengthen water and climate resilience.
Research reveals that the visual systems of mice and monkeys follow the same efficient coding principle, but process different sensory inputs. This principle explains why mice have stronger responses to movement due to their coarse patch-based vision.
Pharmaceutical contamination in soil and air has severe ecological impacts, affecting animal, plant, and microbial communities. The review highlights the need for interdisciplinary research to understand the dynamics of pharmaceuticals in soil and their long-term implications for ecosystem health.
The journal aims to pioneer a holistic understanding of disease as a dynamic ecosystem, integrating study of micro-environment, microbiota, metabolite, nervous system, and pathophysiology. Pathology Research covers a broad spectrum of pathology-related disciplines, including surgical and molecular pathology, artificial intelligence in ...
Researchers have found that Astragalus polysaccharide protects against ischemic stroke by modulating the gut-brain axis, a two-way communication network between gut microbes and the brain. The compound also reduces inflammation and preserves neurons, suggesting a new route for treating the world's leading cause of long-term disability.
Researchers at Kumamoto University have created a mobile drug delivery platform using polyrotaxanes to simplify targeting the liver. The platform achieves cellular uptake efficiency comparable to conventional systems, while reducing manufacturing complexity.
Researchers at PolyU have engineered a novel tunnelling field-effect transistor using 2D nanomaterials, breaking through the 60 mV decade’ boundary to create ultra-low-power, high-performance ICs essential for emerging AI chips. The breakthrough paves the way for energy-efficient computing and next-generation AI chips.
Cobalt-based electrocatalysts have shown high efficiency in reducing nitrate to ammonia, with some achieving 100% Faradaic efficiency. Researchers have discovered alloying cobalt with other metals and engineering crystal structures can fine-tune the reaction pathway to favor ammonia production.
Researchers discovered a natural compound, hederagenin, that slows kidney aging in diabetes by reversing epigenetic silencing of the anti-aging gene Klotho. Hederagenin reduces Klotho promoter methylation, restoring Klotho protein levels and curbing cellular senescence.