A new study shows that combining biochar application with moderate water table management can significantly reduce greenhouse gas emissions from agricultural peat soils. Biochar consistently lowers carbon dioxide emissions and suppresses methane production, making it a promising strategy for climate mitigation.
Researchers found that tumor genetics alone did not explain which patients responded to combination therapy, but rather the tumor's immune environment. Patients with active networks of cancer-killing T cells were more likely to benefit from treatment, while those with dense clusters of plasma cells were less likely.
Researchers identify calcium as a key chemical signal that triggers immune cells during obsessive-compulsive and anxiety-related behaviors. This discovery establishes a new framework to study how anxiety arises and persists through calcium signals in microglia, potentially leading to targeted therapies.
Scientists at MUSC Hollings Cancer Center mapped the architecture of healthy breast tissue to uncover early biological changes linked to cancer risk. The study found that body weight and breast density shape the underlying structure of breast tissue, offering new clues about how cancer risk may develop long before tumors form.
Researchers discovered a powerful molecule called miR-181d that weaks tumors and helps the immune system fight back against glioblastoma. The study found that tumors in 'exceptional responders' contain higher levels of miR-181d, which blocks cancer cells' ability to repair DNA damage.
The Frontiers Planet Prize has announced its 25 National Champions, who offer scalable, evidence-based solutions to the planetary crisis. The report highlights the urgent need for national and multilateral policies to incorporate these pioneering scientific solutions.
Researchers uncovered previously unknown features in the limb musculature of the macaroni penguin that help explain its efficient movement on land and underwater. The study found modified key wing muscles and a unique configuration of shoulder muscles giving penguins an 'underwater flying' wing stroke.
Researchers have found that apples evolved through ongoing interactions with wild species, shaping key characteristics such as flavor and disease resistance. Wild apple trees remain a critical resource for developing new varieties better suited to withstand disease and climate change.
The research team developed a novel AI pathology analysis system named PRET that can accurately recognize multiple types of cancer using only a minimal number of samples. PRET outperformed existing methods in 20 tasks, achieving high diagnostic accuracy rates and stable generalizability across different populations and regions.
A large cohort study found that older adults who report difficulty standing up from a chair are more likely to experience mental health challenges, joint problems, and decline in quality of life. The study analyzed data from over 50,000 adults aged 50 and above across 15 European countries.
Researchers developed a cancer assessment tool that can identify high-risk patients and specific cell populations linked to their risk. The tool, called scSurvival, predicts survival outcomes more accurately than traditional methods by analyzing single-cell data at cellular resolution.
A new study found that people with Parkinson's disease and those in its prodromal stage often report 'brain fog' despite normal objective cognitive scores. The researchers suggest targeting anxiety and depression may help improve quality of life.
A new framework uses satellite imagery and machine learning to detect tillage practices over large areas and long time periods. The approach has been used to estimate tillage percentage across the U.S. Midwest from 2000 to 2022, revealing clear differences in no-till adoption by crop and region.
The SETI Institute's new initiative explores the global scientific, philosophical, and societal implications of discovering life beyond Earth, connecting experts in various fields. The Discovery and Futures Lab aims to anticipate and guide humanity's responses to this discovery.
A new method called scSurvival uses single-cell genetic data to identify which cells inside a tumor are most strongly linked to patient survival. The approach pinpoints harmful and helpful cell populations that can drive disease progression, enabling better understanding of why patients with the same cancer have different outcomes.
The book highlights the importance of sustaining innovation in sectors such as semiconductors, biotechnology, and critical minerals to drive economic growth and national security. By rebuilding domestic manufacturing and leveraging new technologies, the US can regain leadership in these areas and capture a $4 trillion market.
Researchers at the University of Colorado Anschutz discovered that cancer drugs impact a specific protein regulating taste buds. This finding could lead to new treatments preserving taste function in cancer patients.
A new study found that FDA 'healthy' labels increase consumer selections of healthier snacks and command a price premium. The study, led by researchers at Oregon State University, examined consumer purchasing preferences for snack products with and without healthy labels.
University Hospitals is the first US health system to achieve ISO 9001 certification for its corporate headquarters and the first in Ohio with all hospitals certified. The achievement demonstrates a systemwide commitment to consistency, accountability, and continuous improvement.
Researchers developed a new method to recover critical minerals using simple magnets, which streamlines the process while reducing energy consumption. The technique exploits small differences in magnetic susceptibility to drive selective transport and separation.
A new study found that high school students who perceive sun protection as inconvenient or uncomfortable are less likely to engage in sun-safe behaviors. Teens who view tanning as enhancing appearance or social appeal also tend to neglect UV radiation protection.
A new FeS2/MoS2 heterostructure design enables rapid water treatment while maintaining long-term stability and efficiency. The system regenerates dual active sites through internal electron transfer, supporting multiple reactive oxygen species for pollutant degradation.
Researchers introduced QCell, a curated collection of 525,000 new quantum-mechanical calculations for biomolecular fragments. The dataset addresses the limited coverage of nucleic acids, lipids, and carbohydrates, enabling reliable simulations of critical biological processes such as DNA dynamics and membrane behavior.
A new study by the University of Helsinki finds that the carbon footprint of milk production is 41% higher when soil carbon changes are included. Soil organic matter can either sequester or release carbon, and its impact on climate change should not be ignored.
Dr. Aditya Bardia has been elected to the American Society for Clinical Investigation for his outstanding contributions to research and patient care in breast cancer treatment. He is advancing precision medicine therapies through antibody-drug conjugates and liquid biopsy technologies.
A Concordia study reveals that black soldier flies can survive and thrive on goose feces, producing valuable biomass for composting and organic fertilizer. The insects' waste also serves as a nutritious fertilizer for duckweed, improving its growth rate and root system.
Researchers mapped how Sox9 guides cartilage formation in mouse embryonic limbs, finding that it dynamically targets different genes depending on developmental timing and cell type. The study provides a foundation for understanding skeletal development and may contribute to future research on bone and cartilage diseases.
A mild chemical strategy enhances interfacial bonding and pore structure in biomass-based magnesium cement materials, leading to improved mechanical strength and thermal insulation. The approach promotes more uniform pore distribution, stabilizes the foam structure within the composite, and reduces environmental burden.
A new study reveals that AI's strength lies in teamwork with humans, processing data but relying on people for context and ethical decisions. The research emphasizes the importance of human oversight and responsibility in AI-driven decision-making.
A study of nearly 6,000 people found that when people are presented with viewpoints they disagree with in a pro-support frame, they tend to be less open to the idea. However, when framed in oppositional terms, they are more likely to engage. Researchers suggest changing argument framing can help improve dialogue.
A new phase in the corona-development has been identified, with recent SARS-CoV-2 variants spreading less rapidly worldwide and BA.3.2 infecting young children more frequently than other strains. This suggests that global immunity from vaccination and infections may be making it harder for new variants to spread.
A new study has found that postmenopausal white women with higher genetic risk of obesity regained weight about two times faster than those with lower genetic risk. Despite this difference, Black women in the study regained weight at a similar rate, regardless of their genetic risk.
A study by Universitat Oberta de Catalunya found that digital platformization leads to a fragmentation of pupils' knowledge, alterations in socio-cognitive conditions, and disruptions in learning times. Teachers report concerns about superficial reading, interrupted didactic continuity, and reduced students' personal involvement.
Researchers at DTU discover three types of lactic acid bacteria that can effectively produce plant-based yoghurt alternatives, inhibiting harmful bacteria and breaking down sugars. The bacteria also improve the product's texture and extend shelf life.
Researchers developed a platinum-based catalyst supported on oxygen-vacancy-rich cerium oxide (Pt/CeO2–Vo) to enhance hydrogen activation. The catalyst achieved a pyrrolidone yield of 95.2% within one hour, with high formation rates and excellent stability.
Mechanobiology reveals how physical forces govern cells, tissues, and diseases, leading to breakthroughs in cancer, fibrosis, orthopedic injuries, and vascular diseases. The field is also pioneering mechanical reprogramming and mechanogenetics, enabling personalized mechanical interventions.
A recent study found that antibiotic-resistant bacteria are present in the gut microbiomes of American black bears in eastern North Carolina. The researchers also discovered that these pathogens can be dispersed through bear feces, making the bears a potential indicator species for environmental changes.
New research from Trinity College Dublin found playing an instrument, taking a foreign trip, and socializing boost cognition in midlife. Lifestyle interventions can strengthen cognitive reserve decades before disease onset.
Researchers found that crabs' iconic sideways walk originated from a single, forward-walking ancestor around 200 million years ago. This rare innovation likely contributed to the ecological success of true crabs by making their escape direction unpredictable.
A new multicenter study finds that reoperative surgical mitral valve replacement demonstrates significant long-term survival benefits over transcatheter mitral valve-in-valve procedures in patients with failing bioprosthetic valves. At five years, rSMVR patients had lower mortality and more favorable valve performance.
A study by Geisel School of Medicine researchers identifies specific macrophage populations that help coordinate anti-tumor immunity, while others support tumor growth. By selectively targeting these immune programs, cancer treatments may be improved without eliminating entire immune cell populations.
A study on Spanish transhumance identifies three distinct types of systems, aligned with agroecological principles, offering insights into sustainable livestock farming. The findings highlight the need for greater political support and a regulatory framework to protect this ancient practice.
Measles outbreaks are accelerating globally, with declining vaccination rates and gaps in routine immunization coverage contributing to the resurgence. The disease can cause serious complications, including pneumonia, encephalitis, and death, particularly in young children and immunocompromised individuals.
Researchers found that brains consider grammatical constituents when anticipating next words, unlike AI systems which rely on predictive context. The study used magnetoencephalography and behavioral tasks to measure brain activity and word prediction accuracy.
The ORNL team is developing AI-enabled pixel detectors that can process massive data streams directly at the source. Spiking neural networks will be used to identify patterns and extract valuable signatures from particle interactions in real time.
SGLT2 inhibitors reduce proximal tubular sodium reabsorption by suppressing NHE3 via the SGLT2-MAP17-NHE3 microdomain. This effect is context-dependent, with distal compensation (NCC upregulation) possible. Clinical evidence shows reduced ascites, fewer paracenteses, and improved natriuresis.
Researchers discovered a biomarker that can predict disease progression and mortality in patients with severe heart failure. Mid-regional pro-adrenomedullin (MR-proADM) levels are associated with greater disease severity, mortality, and heart failure events.
The Kura-Araxes culture's multi-ingredient cuisine highlighted the central role of dairy products, fruit, and grape-based beverages. The discovery sheds new light on the daily life and culinary traditions of these communities, suggesting a low level of social stratification.
Researchers have discovered a new species of basal medusozoan, Paleocanna tentaculum, in fossil specimens found in Saint-Joachim, Quebec. The ancient creature, closely related to modern jellyfish, is a rare find due to the limited preservation of soft-bodied organisms.
The study sequenced and decoded the complete genetic information of rose plants, producing the first rose pangenome. This reveals a complex evolutionary history shaped by gene transfer and environmental adaptations.
A team of scientists at the Hackensack Meridian Center for Discovery and Innovation (CDI) has made a significant breakthrough in treating deadly non-tuberculous mycobacteria (NTM) infections. They have developed new compounds, including rifamycin candidates, which show promise in treating M. abscessus and other rapidly growing NTMs.
Researchers at Umeå University have identified NUP98 and NUP153 as key host factors in orthoflavivirus infection, which replicates in the cytosol of human cells. The proteins play a crucial role in viral replication and protein production, and their interaction with viral RNA regulates structural and non-structural protein ratios.
Binghamton University's new initiative aims to advance artificial intelligence for the public good by educating students on foundational AI principles, workforce applications, and ethical considerations. The three-year, $900,000 program includes a free online microcredential and student research opportunities.
The study found that women's cardiovascular disease is biologically different from men's, with greater sensitivity to cumulative risk exposure and more severe downstream consequences. Researchers emphasize the need for continued investment in CVD research to address sex-specific disease mechanisms and life-course risk accumulation.
The Individual Brain Charting project has released its fifth update with a new set of cognitive tasks, expanding the dataset to 40 hours of scanned data per participant. This provides an exceptionally rich resource for studying individual variability in brain organisation and understanding brain function.
A new international survey reveals that adults with hypophosphataemic osteomalacia face a substantial disease burden, often under-recognised. The study calls for improved awareness, education, and coordinated care to ensure timely diagnosis and optimal treatment.
A study by the University of Kansas found that high school journalists learn business skills through practice and experiential learning, even if business concepts are not directly addressed. Student media advisers reported financial pressures and stressed the need for improved financial literacy education.
The study uses CRISPR/Cas9 to modify the transcriptional repressor SlMYB32, leading to increased flavonol and flavanone production in tomatoes. Key genes associated with these compounds are up-regulated in SlMYB32 mutants.
Terrence Sejnowski receives Scientific Breakthrough Award for his foundational development of Boltzmann machines, providing the architectural bedrock for deep learning and generative AI. His work has had a profound impact on modern artificial intelligence and tools like ChatGPT.
Researchers developed a new scale to measure the use of evidence in decision making, capturing four sources of evidence. The Evidence-Based Management Source Utilization Scale (EBM-SUS) shows promise for increasing transparency, accountability, and effectiveness in organizational management.