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Science News for August 29, 2026


“Overwhelmingly positive” results reported with a virtual e-health system (VIRTUES) to monitor cardiac implantable electronic devices

A virtual e-health system (VIRTUES) has been found to be as safe and effective as standard care for monitoring cardiac implantable electronic devices, with significant cost savings and patient satisfaction. The system uses transmission reports from the patient's device to provide real-time monitoring and communication with the physician.

Remote exercise-based cardiac rehabilitation − an additional option but not a replacement for centre-based rehabilitation

Remote exercise-based cardiac rehabilitation shows promise as an additional option for patients, but does not replace centre-based rehabilitation. The study found that remotely delivered exercise improved physical capacity and was used by a substantial proportion of patients, despite not increasing overall participation.

REACT reveals that silent atherosclerosis already affects 1 in 13 young adults aged 18 to 29 and progresses rapidly from the menopause

The REACT study reveals that 57.1% of participants aged 18 to 70 had atherosclerotic plaques, despite no symptoms or previous diagnosis. Most people with coronary atherosclerosis also had the disease in other arteries, making portable ultrasound devices a promising screening tool.

Cholesterol-lowering medication reduces major cardiovascular events by 30% in older people without known cardiovascular disease

A new study found that atorvastatin reduces major cardiovascular events by 30% in people aged 70 and older without known cardiovascular disease, diabetes, or dementia. However, it did not improve disability-free survival. The results inform treatment guidelines for older adults, who are underrepresented in previous trials.

Monoclonal antibody targeting interleukin-6 achieves sustained reductions in inflammation biomarkers through six months

A phase 2 clinical trial found that a monoclonal antibody targeting interleukin-6 achieved sustained reductions in inflammation biomarkers for six months in patients with chronic kidney disease. The therapy, known as pacibekitug, was well-tolerated and showed favorable effects on additional biomarkers associated with cardiovascular risk.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·TypeRandomized controlled/clinical trial·DateAug 29, 2026

LDL cholesterol lowering with evolocumab before percutaneous coronary intervention for acute myocardial infarction (AMUNDSEN)

Starting evolocumab before or during percutaneous coronary intervention for acute myocardial infarction significantly reduces LDL cholesterol levels. However, this strategy does not improve short-term clinical outcomes, including death and cardiovascular hospitalization, during the first year. The study suggests that lowering LDL chole...

SourceJAMA Network·JournalJAMA·DateAug 29, 2026

Intensified antiplatelet therapy plus direct oral anticoagulants increased bleeding in patients with atrial fibrillation after a heart attack

Atrial fibrillation patients who have had a heart attack may be at increased risk of bleeding if given potent antiplatelet therapy combined with direct oral anticoagulants. The EPIDAURUS trial found no significant benefits regarding cardiovascular events, suggesting these treatments may not be necessary for this patient population.