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Brightsurf delivers daily science news discoveries, articles, and the latest scientific breakthroughs. Your trusted source for science news today, covering nature news, science & technology, and scientific discoveries from leading research institutions worldwide.

Fungal infections: A surprising downside of the immune response

Researchers discovered that immune cells' vesicles, meant to destroy pathogens, actually promote the survival of Candida albicans in the bloodstream. The vesicles, carrying antimicrobial molecules, shield the fungus from immune attack by altering its surface, making it harder for immune cells to recognize.

SourceLeibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute -·JournalJournal of Extracellular Vesicles·TypeExperimental study

Switching chiral phonons with electricity

Scientists at PSI discovered chiral phonons, which exhibit handedness, and now show that an electric field can control their handedness. The researchers created a tiny device using ferroelectric barium titanate and demonstrated the ability to switch the handedness of phonons at room temperature and low voltage.

SourcePaul Scherrer Institute·JournalNature Materials·TypeExperimental study

Elke Deuerling receives Sir Hans Krebs Medal 2027

Elke Deuerling, a renowned molecular biologist, has been awarded the Sir Hans Krebs Medal 2027 for her groundbreaking research on protein balance and proteostasis. Her work focuses on deciphering the molecular processes that maintain cellular protein levels, ensuring the health and viability of organisms.

Cambridge scientist uncovers how much protein we actually need and the best sources (for both planetary and public health)

A new paper from Cambridge scientist Dr Chris Macdonald explores the benefits of higher-protein diets, including lower mortality risk, improved mental health, and enhanced cognition. The study also reveals the best plant-based sources of protein, with tofu ranking highest overall.

SourceLucy Cavendish College, University of Cambridge·JournalFrontiers·TypeSystematic review

New molecules against hard-to-treat tumors

Researchers developed small molecules that activate macrophages to attack cancer cells, weakening the tumor's defenses against the immune system. The molecules, called Phagocytic Synapse Enhancers, were tested in cell cultures and animal models and showed promising results, slowing tumor growth and extending survival.

SourceUniversity of Basel·JournalCancer Research

New computational method pushes cryo-EM beyond traditional resolution limits

Researchers developed PASR, a computational method that recovers higher-frequency structural information from cryo-EM datasets, improving map quality and enabling higher-resolution reconstructions. The approach may reduce microscope usage time and data-storage demands for analyzing large, flexible, or heterogeneous biological complexes.

SourceNational Institutes of Natural Sciences·JournalIUCrJ·TypeExperimental study

Scientists reveal how blood cells release key signalling lipid

Researchers from NUS Medicine and St. Jude Children's Research Hospital have discovered how blood cells release S1P, a key signalling lipid, into the bloodstream. S1P plays a crucial role in keeping blood vessels healthy and supporting normal cell function. The study used cryo-electron microscopy and computer simulations to capture a d...

Pumping antibiotics out: A new route to bacterial drug resistance

Researchers at the University of Osaka have identified a previously unknown mechanism that allows the bacterium Streptococcus pneumoniae to export the antibiotic fosfomycin. The discovery provides new clues to drug resistance and could lead to the development of more effective treatments for bacterial infections.

SourceThe University of Osaka·JournalProceedings of the National Academy of Sciences·TypeExperimental study

Researchers uncover molecular strategy for efficient triplet generation

Triplet excited states in organic molecules play crucial roles in various applications. Researchers have identified a molecular strategy for balancing competing requirements in organic donor-acceptor systems, controlling conformational dynamics to determine triplet generation efficiency. The study reveals that an intermediate donor-acc...

SourceDalian Institute of Chemical Physics, Chinese Academy Sciences·JournalJournal of the American Chemical Society·TypeCommentary/editorial

Nature Biotechnology | Insilico’s AI-driven IPF candidate rentosertib shows potential for biological age reversal, as assessed by six proteomic aging clocks

Researchers evaluated biological age using six internationally recognized proteomic aging clocks, finding a reduction in predicted biological age among patients treated with rentosertib. The drug also showed promising dose-dependent reversal of Forced Vital Capacity (FVC), a measure of lung function declining with age.

SourceInSilico Medicine·JournalNature Biotechnology

Making polymers fluoresce with stress

A simple blending strategy enables reversible fluorescence in block copolymers, allowing visualization of mechanical stress without altering material properties. The approach preserves mechanical properties and offers a practical route for stress-sensing functions in existing polymer materials.

SourceInstitute of Science Tokyo·JournalAdvanced Materials·TypeExperimental study

Researchers create polar wurtzite nitride semiconductor NbAlN

The team successfully grew single-crystalline polar wurtzite NbAlN thin films on GaN substrates, preserving the wurtzite crystal structure and metal polarity. This discovery expands the options for designing carrier density in GaN heterostructures, offering a new family of transition-metal-containing polar nitride semiconductors.

SourceTokyo University of Science·JournalAdvanced Materials·TypeExperimental study

Do black holes have hidden hair? Scientists find a new way to check

Researchers at Nagoya University have developed a method to detect hidden matter around black holes by analyzing changes in ringdown waves. The study found that hidden matter affects ringdown differently depending on its pressure arrangement around the black hole.

SourceNagoya University·JournalJournal of Cosmology and Astroparticle Physics·TypeComputational simulation/modeling

New low-temperature coating strategy for tougher and conductive lightweight magnesium

Researchers developed a low-temperature steam-assisted process to create durable, conductive spinel coatings on magnesium alloys for harsh acidic environments. The coating achieved ultralow corrosion current density and high sheet resistance, making it suitable for next-generation energy storage and conversion technologies.

SourceShibaura Institute of Technology·JournalSurface and Coatings Technology·TypeExperimental study

A neural brake on adult glioma progression

A new study reveals that inhibitory brain circuits can suppress adult glioma growth by reducing calcium activity inside tumor cells. Inhibitory neurons form synaptic contacts with glioma cells and reduce tumor cell proliferation and survival in preclinical models.

SourceNagoya City University·JournalNeuron·TypeExperimental study

Deconstructing LSD for therapeutic discoveries

University of California, Davis researchers successfully synthesized new compounds with reduced hallucinogenic and cardiotoxic effects, identifying one compound with antipsychotic-like effects. By systematically deconstructing LSD, they uncovered the importance of the phenethylamine-like traits in producing hallucinogenic effects.

SourceUniversity of California - Davis·JournalProceedings of the National Academy of Sciences

Is self-processing conserved across primate species' brains?

Researchers found strong similarities in small-scale structural properties and gene expression patterns between humans and macaques, but more differences in large-scale connections. Chimpanzees occupy an intermediate position between macaques and humans, with brain systems showing reorganization in sensory, motor, and internal informat...

SourceSociety for Neuroscience·JournalJNeurosci

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