Researchers at NewYork-Presbyterian/Weill Cornell developed a simple and effective technique to reconstruct key anatomical structures that ensure continence. The procedure added only two to five minutes to standard robotic prostatectomy and achieved a 95% continence rate among patients 16 weeks after their surgeries.
A UCLA study found that three common prostate cancer treatments affect men's lives in different ways, with varying degrees of erectile dysfunction and urinary symptoms. The study tracked 580 men for five years and used a web-based data collection system to gather accurate information.
Researchers found that the androgen receptor plays a key role in bladder cancer development, which explains why it affects men more than women. The discovery opens doors to new treatment options and may help doctors predict tumor recurrence.
Research suggests that phytochemicals in cruciferous vegetables, such as broccoli and watercress, can stop human prostate cancer cells from growing and inhibit the formation of blood vessels that feed tumors. This study provides promising preliminary evidence for the potential anti-cancer properties of these vegetables.
Men with lower educational levels experience a significant drop in quality of life after prostate cancer treatment compared to those with more education. The study controlled for various factors, including income and healthcare access, to show that low education alone is associated with lower quality of life.
A study of 372 men with prostate cancer found that 49% had osteoporosis, with those receiving hormone therapy and having undergone radical prostatectomy being at highest risk. The authors suggest that daily calcium intake could be used as a prognostic factor for osteoporosis in these patients.
A detectable PSA level is first indicator of recurrent prostate cancer after radical prostatectomy, with a doubling time of less than three months indicating imminent death from prostate cancer. Patients with longer doubling times are at significant risk for disease recurrence and cancer-specific death.
Researchers at Johns Hopkins Medicine have developed a motor that can safely power remote-controlled robotic medical devices for cancer biopsies and therapies guided by magnetic resonance imaging. The motor, dubbed PneuStep, is made entirely out of plastics, ceramics, and rubber and is driven by light and air.
A study by Duke University Medical Center researchers found that obese and overweight men are more likely to have aggressive prostate cancer than biopsy results indicate. This discrepancy may lead to inadequate or inappropriate treatment, emphasizing the need for more accurate biopsies.
Researchers at UT Southwestern Medical Center have developed a Magnetic Anchoring and Guidance System that uses magnets to attract and manipulate laparoscopic surgical tools. This new technique allows for magnetically maneuvering laparoscopic instruments inserted into the abdominal cavity through the bellybutton or throat.
The European Association of Urology (EAU) has recommended Sutent as a first-line treatment for patients with metastatic renal cell carcinoma. Clinical trials have shown that Sutent improves progression-free survival by more than doubling the median PFS compared to interferon-alpha. The new guidelines also highlight Sutent's higher obje...
Urologists are urging transport companies and family doctors to develop strict guidelines for staff with kidney stones, as sudden attacks can cause debilitating pain and pose safety risks. The authors have devised their own guidelines, but stress the need for governing bodies to create formal ones.
A new study published in International Braz J Urol found that exposure to hot baths or hot tubs can lead to male infertility. However, the effects can be reversible if the practice is discontinued for at least three months. The study showed a significant increase in sperm motility among responders, with a mean increase of 491 percent a...
Men who receive false-positive prostate cancer results experience heightened anxiety about their risk of developing the disease and report issues with sexual function. The study emphasizes the importance of discussing the pros and cons of screening with patients to minimize adverse effects on quality of life.
A VA researcher has developed a method to identify men at risk for high-grade prostate cancer, reducing the need for unnecessary biopsies. The study found that a high PSA adjusted for prostate size and Gleason scores above 7 indicate a higher risk of life-threatening prostate cancer.
Scientists have identified a severe form of benign prostatic hyperplasia (BPH) tied to a gene called JM-27. A blood test detects high levels of this protein, indicating more severe symptoms. This discovery could lead to earlier diagnosis and targeted treatment for bladder-related complications.
Researchers at UT Southwestern Medical Center have found a new biomarker test that can predict the recurrence of bladder cancer in patients. The test uses molecular biomarkers to identify patients who are more likely to experience cancer recurrence, allowing for personalized treatment options.
A study published in BJU International found that a topical anaesthetic spray delayed ejaculation by five times as long, with participants experiencing an average delay of four minutes. The TEMPE spray, containing lidocaine and prilocaine, showed promising results in delaying premature ejaculation.
A survey of 129 men with testicular cancer found that 24% chose to bank their sperm before treatment, despite high costs and relatively low usage. Single men were twice as likely to bank their sperm, and those who did had better fertility outcomes after treatment.
A multicenter study found that finasteride artificially lowers PSA levels in younger men taking it for hair growth, impacting diagnosis accuracy. The study calls for new clinical guidelines to account for this effect when evaluating PSA results.
A study at the University at Buffalo found that synthetic cannabinoid AM-1346 can improve fertility in male smokers with poor semen quality, doubling fertilizing capacity. Researchers believe a communication imbalance between cannabinoid and cholinergic receptor systems may be responsible for nicotine-induced infertility.
Research from the Flint Men's Health Study found that African-American men with prostate cancer were more likely to report a family history of both diseases among siblings. This increased risk was particularly notable for having a brother diagnosed with prostate cancer and a sister diagnosed with breast cancer, highlighting the importa...
A clinical trial of gene transfer therapy for erectile dysfunction found significant and sustained improvements in patients who received a transfer gene called hMaxi-K. The therapy works by creating additional potassium channels in smooth muscle cells, relaxing the muscle and allowing blood flow required for an erection.
Researchers found that a radical prostatectomy can be a viable option for select octogenarian patients with localized prostate cancer. The 10-year survival rate was similar to that observed in healthy patients 60-79 years old undergoing a radical prostatectomy.
A cohort study of over 2,000 Air Force veterans found that dioxin exposure was associated with a lower incidence of benign prostate hyperplasia (BPH) and decreased testosterone levels. The study suggests a link between dioxin exposure and endocrine disturbances in the male reproductive system.
A survey of over 700 family doctors found that nearly two-thirds provide PSA tests on request, despite lack of evidence supporting its effectiveness. The study highlights the need for better training and targeted guidance to influence testing patterns and improve patient outcomes.
A combination therapy of tolterodine ER and tamsulosin resulted in statistically significant treatment benefits for men with overactive bladder and benign prostatic hyperplasia. Eighty percent of patients reported improvement in symptoms, compared to 62% on placebo, highlighting the potential for combination therapy in managing lower u...
Researchers at Johns Hopkins Kimmel Cancer Center found overproduction of myosin VI in prostate tumor cells and precancerous lesions. Silencing myosin VI in lab studies reduced cell invasion, suggesting its critical role in starting and maintaining malignant properties of most human prostate cancers.
Researchers found that a man's PSA velocity, or rate of increase in PSA levels, can accurately predict tumor aggression and danger. Men with lower PSA velocity have a 92% chance of not dying from prostate cancer within 25 years.
Researchers found that nearly all tumor cells in the bone marrow of early-stage breast cancer patients have a putative breast cancer stem cell phenotype, increasing the risk of disease progression. This study provides evidence that these stem cells may be responsible for metastases and has significant implications for cancer treatment.
Researchers analyzed nine trials involving 693 patients and found that treatment with calcium-channel blockers or alpha blockers increased the chances of passing urinary stones by 65%, making these medications an effective alternative to surgery.
A study by Memorial Sloan Kettering Cancer Center found that high-dose intensity modulated radiation therapy (IMRT) achieved a 89% disease-free rate for patients with prostate cancer after an average of 8 years. The treatment also showed improved quality of life by reducing side effects and maintaining urinary continence.
A new study found that black patients with bladder cancer are 35 percent more likely to die of the disease than white patients. Black women in particular had more aggressive tumors and lower survival rates compared to white men and women and black men.
A University of Michigan Health System study found that while more small kidney tumors are being detected and treated, the death rate from kidney cancer is not decreasing. The researchers suggest re-examining treatment strategies for patients with small renal masses, as surgery may not be the best option for everyone.
Research at Mayo Clinic found that 16% of men experience moderate or higher pain during prostate biopsies, with the injection of lidocaine causing more pain than ultrasound insertion. The location of biopsy, specifically the prostate apex, is a significant predictor of pain scores.
A recent study found that South Asian men experience more urinary problems than their white counterparts, including difficulties storing urine and urinating frequently. Despite this, they are less likely to seek medical attention or advice for these symptoms.
Researchers found a daily dose of 150mg bicalutamide reduced disease progression risk by 44% and overall death risk by 35% compared to radiotherapy alone. This non-castration-based therapy shows similar survival rates, potentially improving quality of life for patients unwilling to undergo castration.
A new study found that over half of men with lower-risk prostate cancer received aggressive treatment, despite active surveillance being a viable option. Men under 55 were more likely to receive surgery, while those aged 70-74 were more likely to receive radiation.
Researchers found that a healthier balance of omega-3 and omega-6 fatty acids can reduce prostate cancer tumor growth rates and PSA levels by 22% and 77%, respectively. The study suggests using EPA and DHA supplements to lower inflammatory response in prostate cancer development.
Scientists at Johns Hopkins believe that heat therapy can selectively target and kill cancer cells by disrupting their nuclear protein scaffolding. Preliminary research suggests that this approach could be effective in treating solid tumors, with the goal of improving cure rates.
Researchers at UCLA have successfully transformed adult stem cells from human adipose tissue into functional smooth muscle cells, which can help regenerate damaged organs like the intestine, bladder, and arteries. The study's findings offer a promising alternative to using patient's own tissue for organ regeneration without anti-reject...
Mayo Clinic researchers found robot-assisted, laparoscopic surgery to be effective in repairing vaginal vault prolapse. The procedure resulted in less recovery time, lower risk of bleeding and pain, and higher patient satisfaction compared to traditional open surgery.
Researchers at Thomas Jefferson University have identified proepithelin as a crucial protein in the spread of bladder cancer. The study found that proepithelin promotes migration and invasion of bladder cancer cells, suggesting it could be a potential target for new drugs.
A large-scale study found that two-thirds of patients stopped using Uprima due to ineffectiveness, with 70% of family doctors agreeing. The study analyzed data from 11,185 patients and showed that the most common adverse reactions were headache and nausea.
A study at UCLA found that pomegranate juice can increase doubling times of PSA levels in men with prostate cancer, allowing for delayed use of hormone therapy. The study involved 50 men who experienced increases in PSA levels after surgery or radiation.
Researchers found that pomegranate juice reduced PSA levels by 30% in patients with recurrent prostate cancer, slowing the doubling time of PSA levels. The antioxidant ellagic acid in pomegranate juice was also shown to increase nitric oxide production and induce programmed cell death.
A study shows that a prostate cancer vaccine, sipuleucel-T, can increase survival by up to four-and-a-half months and provide a greater than three-fold increase in survival at 36 months compared to patients in the placebo group. The vaccine was well-tolerated with mild adverse effects.
A large-scale study found that smoking and obesity are strongly associated with a greater risk of erectile dysfunction (ED), while regular physical activity lowers the risk. Regular exercise was found to reduce ED risk by 2.5 times, emphasizing the importance of adopting a healthier lifestyle.
Surgeons at UT Southwestern Medical Center have recorded some of the most successful patient outcomes nationally for patients with rare and complex type of kidney tumors. The five-year survival rate was among the highest, while one-year survival rate is 78 percent.
A University of Minnesota study found that exercise in a machine simulating gravity can reduce the risk of developing kidney stones in astronauts. Researchers used identical twins to test the effect of exercise on urinary calcium levels, and the results suggest a potential solution for preventing this painful condition.
A new test has been developed to detect prostate cancer spread in lymph nodes at an earlier stage, which may lead to better treatments and improved patient outcomes. The test was found to be more sensitive than existing methods and associated with increased recurrence and decreased survival rates.
A study comparing Japanese American and white male patients who received hormone treatment for prostate cancer found that the former had a significantly higher five-year overall survival rate of 66% compared to 42%. The result was not affected by cancer stage or PSA levels, suggesting genetic and lifestyle factors may play a role.
A study found that early exposure to estrogen or BPA increases the risk of precancerous lesions in the prostate. Researchers discovered that this leads to epigenetic reprogramming, altering gene expression patterns that promote prostate disease with aging.
Researchers found that St. John's Wort increased bladder contraction intervals in rats with bladder inflammation, reducing bladder hyperactivity and associated pain. The study suggests that the herbal supplement may be a viable treatment option for women suffering from interstitial cystitis, affecting 700,000 Americans.
Researchers found Botox injections to improve urinary tract symptoms and quality of life in men with enlarged prostates. The treatment reduced prostate size through apoptosis, improving urine flow and decreasing residual urine.
A recent study conducted by the UCLA School of Medicine found that testosterone replacement therapy does not negatively affect the prostate or its tissues in hypogonadal men. The six-month trial involved 41 men with low testosterone levels and showed no changes in prostate tissue, PSA, or DHT levels.
A clinical trial found that injecting stem cells from a woman's own muscle may effectively treat urinary incontinence. Five of seven patients reported significant improvements in bladder control and quality of life with no serious adverse effects. A follow-up study is planned to determine the optimal dose for effective treatment.
A new marijuana-derived drug, IP 751, has shown significant promise in suppressing bladder overactivity and alleviating painful symptoms in animal models of interstitial cystitis. Researchers at the University of Pittsburgh School of Medicine developed a liposome-based delivery system to overcome the hydrophobic properties of the drug.
Astellas Pharma US, Inc. has been recognized by the American Urological Association for its continued support of education and research initiatives in urology. The company's commitment to improving urologic care through innovative pharmaceutical products is being acknowledged by the AUA.
A study at Mayo Clinic found that patients treated with shock wave therapy for kidney stones were at higher risk of developing diabetes and hypertension, with risks nearly four times and one-and-a-half times respectively. The researchers believe the association may be due to damage inflicted on the pancreas or scarring in the kidneys.