A study by UCSF analyzed emergency department visits and found that many minor genital injuries can be prevented through educational and product safety approaches. The research identified specific age groups and consumer products as risk factors, offering insights into preventing such injuries.
A Phase 1 clinical trial has shown encouraging results for stereotactic radiosurgery in treating localized primary renal cancer, with 94% of patients experiencing decreased or stable disease and limited side effects. The non-invasive treatment technique may represent a potential new option for patients who have limited treatment options.
A study by Loyola Medicine found that only 4.8% of web sites describing prostate cancer were written below a high school reading level, highlighting the need for easier-to-read patient education materials.
The American Urological Association has released four new clinical practice guidelines aimed at improving the quality of patient care. The guidelines cover diagnosis and treatment of overactive bladder, adult urodynamics, asymptomatic microhematuria, and vasectomy.
A new study by The Journal of Urology reports that outpatient urological surgical procedures performed in ambulatory surgery centers and physician offices are significantly less costly than hospitals. On average, payments for these procedures were up to a third lower when done outside hospital settings.
Physicians from UH Rainbow Babies & Children's Hospital will present on combating minority obesity, improving perinatal health in Ohio, and treating rare testicular cancer in adolescents. The presentations aim to address the magnitude of the obesity crisis and its impact on minority populations.
A recent study suggests that active surveillance is a viable alternative to surgery for small kidney masses, offering similar cancer outcomes in the short and intermediate term. Researchers found that patients under active surveillance had a growth rate of 0.21cm per month, with 53% showing no growth.
Researchers found that high levels of activated Stat5 protein in prostate cancer after surgery are associated with increased risk of recurrence and death. The study suggests Stat5 could serve as a biomarker to help guide patients and physicians for future treatment.
Researchers discovered a new function of PARP-1 that regulates both DNA damage repair and androgen receptor activity, suggesting that inhibiting this enzyme could slow prostate cancer growth. This finding provides a new approach to treating advanced prostate cancer, which currently has limited treatment options.
Two USC research groups awarded $2.38M and $220K to study epigenetic drivers of cancer and how NSAIDs prevent colorectal cancer. A third group aims to develop new drugs to inhibit 'undruggable' target molecules.
New studies report that robotic-assisted bladder procedures and minimally invasive colorectal operations can improve outcomes in older patients. Robotic-assisted bladder surgery, which was previously not offered to patients over 80, showed a seven-day hospital stay and only three complications within 90 days.
Researchers at Wake Forest Baptist Medical Center have made a breakthrough in helping infertile, premenopausal women produce enough eggs to become pregnant. By stimulating ovarian cell production using an in vitro rat model, they were able to generate early-stage eggs that could be fertilized.
Researchers at Thomas Jefferson University found that contrast-enhanced ultrasound detected higher-grade prostate cancers in 55% of patients, compared to 17% with conventional biopsy methods. The technique uses microbubbles to measure changes in blood flow and requires fewer needle biopsies.
Researchers at UC San Diego School of Medicine found that single-site laparoscopic surgery reduced pain and narcotic use in kidney cancer patients. The study compared LESS with traditional multiport laparoscopy in 74 patients, showing a 40% reduction in pain rating and 50% less medication need.
A recent study by Henry Ford Health found that women are more than twice as likely to suffer infections related to kidney stones and other urinary blockages. The study also showed significantly higher rates of complications following urgent treatments for the condition.
Scientists have discovered a complex positive feedback loop in penile nerves that triggers waves of nitric oxide to keep the penis erect. This process, which involves phosphorylation, enables the sustained release of nitric oxide and maintains erection.
A new study in The Journal of Urology presents promising results on the use of MRI to assess eligibility for active surveillance in men with clinically low risk prostate cancer. The findings suggest that clear tumor visualization on MRI is predictive of disease status upgrades on confirmatory biopsy, highlighting the potential of MRI t...
A recent study by Mayo Clinic researchers found that men with high levels of 'cancer-specific anxiety' after prostate cancer surgery are more likely to experience low sexual satisfaction and depression. Counseling may be beneficial in addressing these concerns and improving quality of life for these patients.
Experts say that younger men with erectile dysfunction are twice as likely to develop cardiovascular disease. A thorough non-invasive cardiovascular disease evaluation is recommended for all men diagnosed with organic ED due to low testosterone levels and other risk factors.
A new study published in The Journal of Urology reports that PSA testing has led to improved survival rates for patients with newly diagnosed prostate cancer that has spread to the bones or other parts of the body. The disparity between African American and Caucasian men has been resolved, with African American men now having a compara...
A study led by Vanderbilt-Ingram Cancer Center finds that black men with prostate cancer receive lower quality surgical care than white men. Black men are less likely to use high-volume surgeons and hospitals, resulting in longer hospital stays and higher mortality rates.
A study found that urology-owned radiation oncology practices in Texas increase patients' travel distances by up to three times due to separate treatment centers. This practice model raises concerns about its impact on healthcare costs and patient care.
Researchers developed a new prostate cancer screening method that combines drug therapy with changes in PSA levels to identify men with high-risk prostate cancer. The study showed that using PSA with these drugs can help differentiate between prostate cancer and benign disease, even in patients with difficult diagnoses.
The study suggests that eliminating the PSA test would result in more men being diagnosed with metastatic prostate cancer, leading to higher mortality rates. Prostate cancer death rates have been reduced by nearly 40% over the past 20 years, largely due to early detection through PSA testing.
A multi-center study found that patients who undergo complete kidney removal are 3.5 times more likely to develop erectile dysfunction compared to those with kidney reconstruction. Researchers suggest that total kidney removal may also increase the risk of metabolic diseases and decrease quality of life.
A study published in Journal of Biological Chemistry found that prostate cancer cells lacking the protein SPDEF are unable to establish colonies at possible sites of metastasis, highlighting a potential biomarker for untreated cancers. Researchers hope to regulate SPDEF expression to prevent cancer cell metastasis.
A new study finds that testosterone-replacement therapy significantly improved symptoms of metabolic syndrome associated with testosterone deficiency in men. Symptoms improved across all three components of obesity, including waist circumference, weight, and body-mass index.
Researchers at the University of Michigan Health System found that patients who receive a mid-urethral sling during prolapse repair have less than half the risk of urinary incontinence. The study suggests that inserting a sling during surgery can significantly reduce urine leakage, but also increases the risk of certain side effects.
A new study found that caring for patients with fecal incontinence costs over $4,000 per person each year, making it a significant economic burden. The condition affects 8.3% of adults and can lead to depression and social isolation.
Researchers at UCLA have identified the genetic mutation responsible for IMAGe syndrome, a rare disorder that stunts infants' growth. The discovery could lead to new ways of blocking rapid cell division and offers a new tool for diagnosing children with IMAGe syndrome.
Researchers discover mutation on same gene responsible for Beckwith-Wiedemann syndrome, a disease characterized by rapid cell division and large size. The finding enables early diagnosis and treatment of IMAGe syndrome, a rare disorder stunting infants' growth.
The study found that kidney stone prevalence nearly doubled from 8.8% in 2007-2010 to 17.6% in 1994, with obesity and diabetes being key risk factors. Maintaining a healthy lifestyle and body weight can reduce the risk of kidney stones.
A recent study published in the journal Urology found that robotic-assisted laparoscopic radical prostatectomy (RARP) is significantly more costly than traditional open surgery. The study, conducted at the University of Pittsburgh Medical Center (UPMC), analyzed data from 473 consecutive patients treated between 2009 and 2010. Research...
Researchers have found that a combination of vitamin D therapy and the BCG vaccine greatly improves bladder cancer survival in a mouse model, with 100% of mice surviving. The study aims to improve treatment outcomes for patients who do not respond to traditional BCG immunotherapy.
Researchers found that statin users had less prostate growth compared to non-users, regardless of whether they took dutasteride or a placebo. The effect was relatively small and tapered off after two years.
A study presented at the American Urological Association Annual Meeting found that early stage prostate cancer treatment can alleviate lower urinary tract symptoms (LUTS) in a subgroup of men. Radical prostatectomy surgery was shown to improve urinary function, while radiation therapy and brachytherapy had less favorable effects.
The Urologic Diseases in America report documents the significant impact of urologic conditions, such as urinary tract infections and prostate cancer, on the American public. The study reveals that these conditions result in substantial healthcare costs, with estimates suggesting $40 billion annually.
A new treatment regimen, accelerated MVAC, has been shown to provide comparable benefits to standard chemotherapy without the same toxicity. This accelerated schedule of six weeks has improved response rates and tolerability for patients with muscle-invasive bladder cancer.
A new UCLA study finds that nerve-sparing surgical techniques and experienced surgeons can improve erectile function after prostate cancer surgery. Surgeons with at least 1,000 cases under their belt and those who actively seek improvement have better outcomes.
A new study by Henry Ford Hospital urologists finds that robot-assisted partial nephrectomy (RAPD) offers fewer complications than laparoscopic partial nephrectomy (LPN), but notes limitations due to data availability on surgical expertise and cancer complexity. The procedure has become the standard treatment for kidney cancer, with co...
A new study found that safer partial nephrectomy surgery is less common among older, sicker, and poorer patients who rely on Medicare or Medicaid for care. This disparity may be due to limited access to care or lower proficiency in performing the advanced surgical technique.
A recent study found that women fare better than men after surgical removal of a cancerous kidney, with fewer post-operative complications, including hospital deaths. However, women are more likely to receive blood transfusions related to their surgery due to the higher rates of bleeding during and after the procedure.
A new study found that patients undergoing radical prostatectomy surgery in accredited teaching hospitals with residency programs experienced fewer complications than those in non-teaching institutions. Those with private insurance also had better outcomes. The study suggests that specialized care and peer-review processes may contribu...
Research at Henry Ford Hospital found that higher hospital volume and surgeon volume both lead to better surgical results, but hospital volume matters more for older, sicker patients. The study analyzed data from 19,225 Medicare patients with prostate cancer who underwent radical prostatectomy between 1995 and 2005.
A recent study found racial disparities in the results of radical prostatectomy for African American patients compared to white patients. The researchers identified five areas where African Americans had poorer outcomes, including blood transfusions, complications during and after surgery, and prolonged hospital stays.
Research suggests that PSA screening can reduce deaths from prostate cancer in younger, healthy men. The benefit of screening is particularly significant in men with risk factors such as black ancestry or positive family history. Screening may be discontinued for elderly men with multiple comorbidities and limited life expectancy.
A literature review highlights the need for a tailored approach to improving quality of life in subpopulations, including African Americans, Latin Americans, Asians, and men who have sex with men. The authors emphasize the importance of considering demographic, socioeconomic, and sexual preference factors in treatment decision-making.
The study found that robot-assisted radical prostatectomy (RARP) resulted in superior outcomes compared to open radical prostatectomy (ORP), including reduced need for blood transfusions and complications during or after surgery. RARP patients were also less likely to have prolonged hospital stays.
Bedwetting in children aged five years or older is common due to excessive urine production, overactive bladder, and inability to wake up. Treatment options include lifestyle modifications, medication, and bed alarms, with the latter showing long-term success in reducing nighttime water production.
A new University of Michigan study found that patients with early-stage kidney cancer who underwent partial nephrectomy had better survival rates than those who received radical nephrectomy. The study analyzed data from 7,138 Medicare beneficiaries and showed that younger or medically compromised patients benefited most from the less i...
A new study suggests that policies to reduce healthcare costs may compromise quality care by depriving patients of needed services. The research found that regions with high rates of inappropriate imaging also had high rates of appropriate imaging, highlighting the need for a more nuanced approach.
A new phase III study comparing the efficacy of Bacillus Calmette Guérin strains Tice and Connaught for non-muscle invasive bladder cancer treatment found that Connaught significantly reduced cancer recurrence rates, with a five-year recurrence-free survival rate of 75% compared to 46% for Tice. The study has the potential to shift the...
A new study found that robotic-assisted surgery for bladder cancer results in fewer deaths, in-patient complications, and reduced need for intravenous nutrition compared to traditional open surgeries. However, the procedure is more costly due to longer operation times and greater use of disposable instruments.
A new study by the University of Leicester has demonstrated that botulinum toxin is an effective treatment for overactive bladder, providing relief from symptoms such as urinary incontinence and urgency. The study found that 4 in 10 women became completely continent again after six weeks and a third remained continent after six months.
Research reveals that a significant proportion of vegetarians and patients with dietary restrictions are unwittingly consuming animal gelatin in medicines. Most patients prefer medicines containing only vegetable products, but over half would take a drug with an animal product if no alternative is available.
Researchers at UCSF have discovered a new class of drugs that target the mTOR protein, which is hyperactive in many forms of cancer. The new drugs block mTOR more completely than previous ones, effectively hobbles cancer cells and prevents metastasis.
Researchers at Thomas Jefferson University found that curcumin suppresses nuclear receptor activators, which can bypass androgen deprivation therapy. Curcumin also reduced cell number and inhibited survival in prostate cancer cells, with similar results seen in mice studies.
Researchers found a significant correlation between coronary artery disease and prostate cancer in a large study, suggesting that heart disease may be a risk factor for the malignancy. Lifestyle changes such as weight loss, exercise, and a healthy diet may help combat both conditions.
A multicenter study found two biomarkers in urine to correlate with aggressive prostate cancer among men on active surveillance. The markers, PCA3 and TMPRSS2-ERG, may lead to a non-invasive test to complement biopsy for predicting disease aggressiveness and progression.
A study found that 30 children with bedwetting had excess stool in their rectums, despite normal bowel habits. After treatment with laxative therapy, 83% of the children were cured of bedwetting within three months.