Researchers found that changes to the gut microbiome in mice were linked to increased intestinal permeability and an increase in food allergy severity. The study suggests that gut health plays a crucial role in how the immune system responds to food allergies, offering new avenues for treatment.
Researchers discovered biomarkers indicating overactivity and dysfunction in the immune system, which can lead to chronic critical illness. Identifying these markers could allow doctors to intervene earlier, leading to shorter ICU stays and improved patient outcomes.
Researchers found that running high-intensity interval training (HIIT) triggers a more inflammatory immune response than cycling HIIT. Cycling produced a similar anti-inflammatory effect compared to running, suggesting it could be used in exercise programs to achieve beneficial effects without tissue damage.
Researchers found that obesity significantly impaired antibody production to a Pseudomonas aeruginosa vaccine in mouse models. The study suggests prioritizing tissue-resident immunity to boost protection against infections. Understanding this relationship addresses a significant gap in current vaccine research.
Anand Balasubramani joins AAI with expertise in scientific publishing, program development, and community engagement. As CSPO, he will shape AAI's scientific agenda and oversee publications, education, and scientific affairs.
New research shows that Rytvela, an anti-inflammatory drug candidate, decreases premature birth and infant mortality when administered after the onset of preterm labor in a preclinical mouse model. The treatment prolongs gestation and fetal growth while allowing newborn organs to develop in utero.
Research suggests that iron deficiency can negatively affect immune cells' response to viruses, leaving lasting effects on lung immune cells. Iron deficiency is linked to conditions like asthma and affects women and young children disproportionately.
Researchers compared four flu vaccines and found varying cellular immune responses across different age groups. The Fluzone High-Dose vaccine outperformed others in older adults, while Flucelvax excelled in younger adults.
Immunology Explained aims to counter false claims and distrust in science by offering accessible content across a new website and social media platforms. The initiative connects immunology to overall health, helping people understand its link to common concerns such as allergies and cancer.
The study identified patterns in T cell receptor repertoires that are specific to both individual dogs and breeds of dog. This could lead to the development of simple blood tests to inform treatment and diagnostic decisions.
A parasitic worm has evolved to suppress neurons in the skin to evade detection, reducing its own survival. Researchers discovered that the worm produces molecules blocking TRPV1+ activity, essential for pain sensation and immune responses, allowing it to infect the skin undetected.
The AAI RESTORE Grants Program will provide one-year grants of up to $100,000 for principal investigators to continue research progress and remain competitive for future funding opportunities. This initiative aims to stabilize immunology labs affected by NIH or other federal grant terminations and freezes in 2025.
CIK cell therapy improved overall and progression-free survival for patients with colorectal cancer, regardless of disease stage. Serum CEA levels can predict treatment response, paving the way for a simple blood test.
A recent study found significant elevated expression of AID enzyme in B cells during Plasmodium falciparum malaria, linking the parasite to the development of Burkitt lymphoma. Elevated AID levels were also observed in Kenyan children with uncomplicated malaria.
A new study published in The Journal of Immunology found that a high-salt diet induces depression-like symptoms in mice by driving the production of IL-17A. Researchers identified gamma-delta T cells as an important source of this protein, which is also linked to depression in human clinical studies.
A new study in The Journal of Immunology reveals how a high-fat diet can impair the immune system's ability to respond to infection. Male mice fed a high-fat diet exhibited impaired neutrophil function, including reduced bacterial killing capacity and abnormal gene expression.
Leading scientific organizations, including AAI and ACP, issue a unified statement emphasizing vaccination's critical role in public health. The statement highlights the extensive scientific foundation and rigorous safety protocols behind vaccine development.
Researchers found that mice receiving both doses of COVID-19 vaccine in the same limb had a faster initial antibody response. Long-term immunity was similar between vaccination approaches.
Research reveals that even a single night of sleep deprivation can alter the profile of immune cells, similar to those found in individuals with obesity. This suggests that the immune system is highly sensitive to sleep patterns and may contribute to long-term inflammatory states and increased risk of disease.
A study published in The Journal of Immunology found that supplementing maternal diet with vitamin E during pregnancy can reduce the development of food allergy and anaphylaxis in newborn mice. This potential breakthrough could help address the alarming increase in peanut allergy among children.