Scientists studied arctic ptarmigan to understand how they cope with extreme environments, discovering their efficient gaits and energy-saving strategies that could improve domesticated breeds' welfare and meat yield. The research aims to prevent future food security crises by breeding birds that can store energy efficiently.
Researchers have developed a 3D picture of a herpes virus protein interacting with human cellular machinery, revealing how the virus hijacks cells to spread infection. This discovery provides new insights into the mechanisms of viral replication and opens up possibilities for preventing or treating viral diseases.
A UK-based team contributed to sequencing the wild strawberry genome, revealing around 35,000 genes that can be used to develop disease-resistant varieties with improved traits. The discovery has significant implications for global food security and could lead to more nutritious and varied diets.
Researchers discovered that humans share a method of sensing oxygen with the simplest known living animal, Trichoplax adhaerens. This finding suggests that the oxygen-sensing mechanism evolved around 550 million years ago, coinciding with the emergence of complex multicellular animal life.
Research finds that a missing molecule essential for nerve cell development impacts GnRH transport, leading to infertility in males. In mice lacking SEMA3A, GnRH becomes stuck in the nose or forehead, preventing proper hormone regulation.
Bioscience researchers have developed a new approach to breeding resistance to late blight in potatoes, using genetic analysis to identify inherently resistant plants. This breakthrough could lead to more durable disease resistance and the creation of GM varieties that can combine resistance to both blight and nematodes.
Drongos in the Kalahari Desert act as lookouts for pied babblers, allowing them to focus on foraging and catch more insects. This mutualistic relationship may represent a rare example of two species evolving from a parasitic to a beneficial interaction.
Researchers have identified a genetic basis for broad-spectrum resistance to the Turnip mosaic virus, which affects key brassica crops. The team's breakthrough could lead to the development of commercial varieties with improved resistance, boosting UK crop yields and food security.
Research reveals that morbidly obese people's fat cells reach a storage limit, leading to changes in metabolism that may increase the risk of diabetes and cardiovascular disease. SFRP1 protein production is linked to these changes, which may trigger metabolic syndrome and other health problems.
Researchers have successfully visualized the human immune system's assassin protein perforin, revealing how it punches holes in cancerous or infected cells. The study provides insights into the protein's structure and function, which could lead to new ways of fighting cancer, malaria, and diabetes.
Researchers have discovered a mechanism to detect bacteria in the womb, opening up new possibilities for preventative treatments. This unique environment relies on a simpler form of immunity called the innate system, as the adaptive response is underdeveloped.
Scientists have identified two plant enzymes that make it easier to extract sugars from wood, straw, and other non-edible parts of plants. This breakthrough can lead to more efficient and sustainable production of biofuels with lower impact on the food chain.
Researchers have used a tuatara's 3D computer model to understand how its jaw joints and muscles work together to prevent tooth damage. The study suggests that humans could benefit from a similar feedback system to reduce the risk of dental implant failures.
The UK researchers have released the first sequence coverage of the wheat genome, comprising 95% of all wheat genes. This data will allow scientists and plant breeders to develop new varieties through accelerated conventional breeding or other technologies.
Researchers have successfully used a drug to reset the body clock of mice, opening up possibilities for treating psychiatric disorders, jet lag, and shift work-related health impacts. The drug works by inhibiting casein kinase 1, a key molecule in the circadian clock mechanism.
Researchers discover small RNAs regulate genes involved in chronic pain, offering a new avenue for developing drugs to treat debilitating conditions like arthritis and back pain. Small RNAs may serve as possible drug targets to restore normal pain thresholds.
Researchers found that a restricted diet reduced accumulation of senescent cells in livers and intestines, and maintained telomeres, preventing age-related disease. The study suggests that adopting a low-calorie diet later in life can still provide benefits.
A new generation of biological scaffolds enables the development of off-the-shelf tissue transplants that can be repaired and renewed like normal tissue. The technique removes cells from natural tissues to leave a biocompatible scaffold made of collagen, allowing patients' own cells to populate and bind to it.
Researchers are developing a method to identify and purify stem cells from patients themselves that can give rise to beating heart cells. This approach aims to create an ideal product for transplant to repair heart damage caused by heart attack or cardiomyopathy.
Researchers are using induced pluripotent stem cells from skin tissue to grow dopamine neurons and study Parkinson's disease. The goal is to better understand the cause of the disease by comparing healthy cells with those affected by Parkinson's.
Researchers have discovered that axolotls possess pluripotent cells in their embryos, similar to those found in mammals, offering a unique opportunity to study the properties of embryonic stem cells. This breakthrough supports the development of regenerative medicine and provides insights into the evolution of stem cell properties.
A new technique developed by Professor Fiona Watt's team allows for the examination of individual stem cells to learn about their biology and screen new drugs. This approach has demonstrated its potential to encourage stem cells to repair damaged tissues.
Researchers found that adding palmitate to mouse stem cells affected their response to sex hormones, influencing the development of visceral versus subcutaneous fat. This discovery sheds light on the fundamental biology underlying obesity-related diseases.
A recent study published in Current Biology reveals that malaria is tens of thousands of years older than previously thought, evolving alongside anatomically modern humans. The research found a clear correlation between the geographic spread of malaria and human migration patterns, suggesting a shared origin and route of spread.
BBSRC funded researchers found that applying Bt to young plants enhances the bacteria's ability to infect insect pests. The study also reveals that the natural abundance of Bt in the environment plays a significant role in its effectiveness.
Scientists have discovered that the aging gene DAF-16 plays a crucial role in determining lifespan, immunity, and stress resistance. The gene is highly active in species with longer lifespans, such as Caenorhabditis remanei, and provides insight into the mechanisms underlying healthy aging.
The zebra finch genome sequencing project reveals insights into the genetics behind brain wiring, learning, and memory. The study also sheds light on evolutionary relationships between bird and mammalian genomes, identifying characteristic features common to both.
BBSRC and NSF announce an intensive workshop, Ideas Lab, to foster new ideas and collaborations on novel biochemical mechanisms for enhanced photosynthesis. The collaboration aims to bring about significant increases in biomass, boosting crop yields and meeting global food and energy security challenges.
Researchers at the University of Oxford have developed a groundbreaking technology that combines high-resolution still images with very high-speed video footage. This innovation is expected to revolutionize various fields, including science, industry, and consumer sectors, by providing access to detailed imaging at an affordable price.
Researchers used radar equipment to observe migrating butterflies and moths flying several hundreds of metres above the ground, highlighting their remarkable abilities. The study found that these insect migrants can travel nearly twice as far and closer to their preferred direction as an insect just randomly drifting downwind.
Researchers found participants who reacted to their opponent executed movements 21 milliseconds faster but with reduced accuracy. This quick-and-dirty system may provide a survival advantage in critical situations.
Researchers from the University of Cambridge have found a way to increase glucomannan levels in plant stems without detrimental effects on plant development or cell wall strength. This discovery could lead to higher yields of fuel from crops, contributing to sustainable and economic biofuels.
Researchers are exploring ways to increase iron and zinc quantities in white flour using high-intensity x-rays. This approach aims to develop nutritious grain varieties that can help address global dietary deficiencies.
A team of researchers has discovered how a cancer drug works, revealing its potential to treat various cancers and improve efficacy. The breakthrough could lead to the design of new cancer drugs that work on the same principle as cordycepin.
Veterinary scientists harnessing 'barcodes' of microbes to develop a single, effective vaccine for all mammals. Tiny variations in TLRs could be key to adapting vaccines across species.
The UK is launching seven new research projects to combat obesity and heart disease, using a combination of public and private sector funding. Researchers will explore the role of probiotics, polyphenols, and cognition in diet-related health issues.
Scientists have received £1 million to research the decline of honeybees, focusing on how bees' behavior outside the hive interacts with factors affecting their health. The project aims to build a model that can predict bee responses to diseases in changing farmed landscapes.
Researchers have discovered molecules that can interfere with insects' sense of smell, confusing them and reducing crop damage. The findings could contribute to food security by preventing damage from insect pests.
Biomimetic nanoparticles are degraded by cathepsin L when entering human cells, compromising their potential to deliver therapeutic proteins. Researchers have developed methods to measure nanoparticle location and state, aiding the design of nanodevices that overcome this degradation.
Researchers have identified SHP-2 as a crucial mediator of insulin-like growth factors' effects on stimulating placental growth. This discovery may lead to new treatments for growth restriction of babies in the womb, improving their health outcomes.
Scientists identify defective immunity in skin as a key factor in skin aging and age-related health problems. The study reveals that older people's skin tissue fails to attract T-cells, leading to reduced immunity and increased risk of infections and cancer.
Researchers identify essential virulence genes in Phytopthora infestans that can be targeted for host resistance. This discovery paves the way for novel strategies to control crop losses and improve global food security.
Researchers are searching for new enzymes in marine microbes that can convert waste products into desired compounds, increasing efficiency and sustainability. The goal is to develop more efficient and sustainable manufacturing solutions for pharmaceuticals and agrochemicals.
The Biotechnology and Biological Sciences Research Council has awarded 16 fellowships to UK researchers, including the first-ever Diamond Fellowship. Professor So Iwata from Imperial College London will study human cell membrane transporters using high-quality x-rays produced by the Diamond Light Source.
Scientists have identified three previously unknown genes in E. coli that are essential for the survival of the bacteria and one out of the three could be implicated in cancer or developmental abnormalities in humans. These genes are also found in numerous other creatures, suggesting a vital role for them across many species.
Scientists have developed a novel protein stabilisation technique using nanoparticles, enabling detailed analysis of previously inaccessible membrane proteins. This breakthrough could lead to more effective drugs and open up exciting possibilities in therapeutic drug discovery.
A £4M funding award will support a multidisciplinary study combining stem cell science and tissue engineering to develop new treatments for bone fractures and orthopaedic problems. The research aims to improve our understanding of skeletal cell activity, scaffold development, and environmental factors that affect tissue regeneration.
Researchers found that learning from experience changes brain circuitry, enabling quicker categorization and decision-making in uncertain situations. The study suggests that previous experience is retained in brain circuits, influencing flexible decisions and actions.
Researchers have found that attentional bias, a key factor in addiction, does not directly control the decision to consume unhealthy items. Instead, conscious rapid decision-making processes following Pavlovian-type cues may be at play. This new understanding could lead to more effective treatments.
Researchers have discovered that fish can harbour and spread PKD, a debilitating condition causing severe inflammation of the kidneys. The discovery paves the way for effective control measures against the disease, which has devastated the UK's fish farming industry.