Researchers create synthetic molecular components that interact with each other to process signals, enabling complex tasks like embryonic development and differentiation. The system allows for analog-to-digital conversion of cellular responses.
Researchers have developed a refined CAR-T therapy called SUPRA-CART that addresses the three major flaws of traditional CAR-T: target specificity, response strength, and adaptive capability. This new system allows for continuous alteration to target different types of cancer cells and can be deactivated in case of severe side effects.
Researchers from Boston University, MIT, UC Berkeley, and CU Boulder develop a method to fabricate silicon chips that can communicate with light, speeding up data transfer and reducing energy consumption. The technology is compatible with current chip manufacturing processes and could revolutionize computing and mobile devices.
Scientists have created a first simple and standardized research tool to study protein aggregation in live cells. The tool, called yTRAP, allows researchers to quantify, manipulate, and track protein aggregates in yeast cells.
Researchers have developed a method using 3D-printed patches infused with cells that offer a promising new approach to growing healthy blood vessels. The patches with pre-organized structure demonstrated improved results in reducing ischemia, while those without organization resulted in a disorganized network.
A new study by Boston University engineer Wilson Wong outlines a simplified platform to target and program mammalian cells as genetic circuits, enabling researchers to make complex computations. The BLADE platform uses DNA recombinases to allow for more targeted manipulation of cells and their behavior.
Researchers at Boston University aim to advance synthetic biology by creating a toolbox of carefully measured and catalogued biological parts. The project will use computing engineering principles to develop an open-source repository of biological pieces that can be used to engineer organisms with predictable results.
A team of engineers from BU and MIT have engineered a wrinkled surface that sheds liquid much faster than a smooth one, reducing contact time by 37%. The innovative approach uses surface texture to reshape drops as they recoil, making surfaces stay drier longer.
A team of researchers has developed a new synthetic polymer supplement that mimics natural synovial fluid, providing superior lubrication and reducing wear on cartilage surfaces. The biopolymer remains in the joint for more than two weeks, unlike current treatments which last only one or two days.
A new synthetic biology method enables reprogramming of mammalian cells, leading to potential therapeutic applications such as stem cell therapeutics and in-cell devices. The approach could also equip cells with higher-order computational tasks for sensing applications.
Researchers developed a disposable microfluidic chip that provides accurate, point-of-care flu diagnosis, replacing expensive lab tests. The chip extracts RNA from Influenza A virus and replicates the sample for detection, producing faster and cheaper results.
Researchers at Boston University have created a 3D model that simulates the growth of cancer tumors, suggesting that softening of cancer cells accelerates proliferation and extends lifetime, leading to rapid tumor growth. The study provides a new quantitative approach to understanding tumor development based on mechanical properties.
Researchers at Boston University have developed a unique material and drug delivery mechanism that can slow the release of anti-cancer drugs over months. The system uses a biocompatible, porous polymer material with air pockets to prevent immediate release in case of water flooding.
Boston University researchers developed a simple diagnostic tool that can quickly identify Ebola and Marburg viruses in blood samples. The biosensor is ultra-portable, fast, and can detect viruses with little to no sample preparation.
Boston University researchers have received a $4.1 million grant to refine their nanoscale, low-cost DNA sequencing method that could lead to individual genome sequencing for less than $1,000. The team's solid state nanopores are uniquely positioned to compete with current DNA sequencing methods for cost, speed and accuracy.
Researchers at Boston University and Harvard discovered that bacteria produce indole to help vulnerable members survive antibiotic attacks, but this comes at the cost of their own well-being. This finding sheds new light on the complexity of bacterial strains and has significant implications for the medical community.
A new nanopore method for DNA sequencing has been developed by Boston University researchers, enabling ultra-fast and low-cost genetic analysis. The technique uses solid-state nanopores to detect DNA molecules, achieving readout rates of up to 200 bases per second.
Researchers found that sub-lethal doses of antibiotics trigger DNA mutations, producing germs resistant to multiple drugs. The study highlights the dangers of incomplete antibiotic treatment and calls for stricter regulations on its use.
Researchers at Boston University have developed a new DNA sequencing method that reduces the amount of DNA required for analysis, eliminating the need for time-consuming and error-prone DNA amplification. This breakthrough allows for faster and cheaper genome sequencing, enabling the analysis of long DNA strands in one swipe.
Researchers aim to understand impact of physical forces on vascular disease and neuro-degenerative disorders by stretching cells on an elastic membrane, simulating natural forces.