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Massachusetts Institute of Technology


Cell circuits remember their history

Researchers at MIT have designed new synthetic biology circuits that combine memory and logic, enabling the creation of long-term environmental sensors and efficient controls for biomanufacturing. These circuits can be used to program stem cells to differentiate into other cell types and provide precise long-term memory.

SourceMassachusetts Institute of Technology·JournalNature Biotechnology·DateFeb 11, 2013

India joined with Asia 10 million years later than previously thought

Researchers at MIT found evidence of two separate collisional events: one 50 million years ago and another 10 million years later. The team analyzed rocks from the Himalayas and discovered a new timeline for India's collision with Asia, suggesting that part of ancient India 'Greater India' was smaller than previously thought.

SourceMassachusetts Institute of Technology·JournalEarth and Planetary Science Letters·DateFeb 6, 2013

Purification on the cheap

A new process developed by MIT engineers can produce clean water at relatively low cost, making it a crucial step towards U.S. energy independence and addressing the issue of produced water from natural gas wells. The technology has been patented and is expected to be commercially available within two years.

Some cancer mutations slow tumor growth

Researchers found that passenger mutations can slow or halt tumor growth when they accumulate. These deleterious mutations can tip the balance in favor of their effects, leading to reduced cell fitness. The study suggests a new approach to treating cancer by enhancing the impact of these mutations.

SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateFeb 4, 2013

A safer way to vaccinate

Researchers at MIT have developed a new type of vaccine-delivery film that gradually releases DNA coding for viral proteins, potentially overcoming safety risks and improving effectiveness. The film is implanted under the skin using microneedles and degrades over time, releasing the vaccine over days or weeks.

SourceMassachusetts Institute of Technology·JournalNature Materials·DateJan 28, 2013

Putting the squeeze on cells

Researchers at MIT have created a device that can deliver RNA, proteins and nanoparticles through cell membranes by deforming cells. The technique has shown success in delivering reprogramming proteins and generating induced pluripotent stem cells with improved efficiency compared to existing methods.

SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateJan 23, 2013

How to treat heat like light

Researchers at MIT have developed a novel method to manipulate heat by employing engineered materials with nanostructured semiconductor alloy crystals. This approach enables the concentration of heat phonons within a specific frequency range, allowing for control over heat flow similar to light waves.

SourceMassachusetts Institute of Technology·JournalPhysical Review Letters·DateJan 11, 2013

Inspiration from a porcupine's quills

Researchers have developed a new class of adhesive materials modeled on the unique properties of porcupine quills. These quills can easily penetrate tissue but are difficult to remove, and studying their mechanism could lead to less-painful needles and adhesives that bind internal tissues securely.

SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateDec 10, 2012

When the first stars blinked on

A team of researchers at MIT analyzed light from a quasar, which is the most distant object known, to study the era of the first stars and galaxies. They found no evidence of heavy elements in the surrounding gaseous cloud, suggesting that the quasar dates back to an era nearing the universe's first stars.

How 'transparent' is graphene?

Recent research at MIT shows that adding a layer of graphene to a surface has little effect on its interaction with liquids, except for extreme cases. The team's findings demonstrate the ability to manipulate wettability while preserving electrical conductivity and optical properties.

SourceMassachusetts Institute of Technology·JournalPhysical Review Letters·DateDec 3, 2012

The music of the silks

Researchers at MIT have created new materials inspired by spider silk and music, offering a potential solution for designing new biosynthetic materials. By analyzing the structural elements of music, they were able to predict the properties of new protein-based fibers, leading to the creation of stronger and more flexible materials.

It pays to cooperate

In a study, MIT physicists found that cooperative yeast members outperform cheaters when competing with bacteria in an experimental setup. This is because cooperators have easier access to sugars and can spread less due to population density constraints.

SourceMassachusetts Institute of Technology·JournalMolecular Systems Biology·DateNov 13, 2012

On the hunt for rare cancer cells

Researchers at MIT developed a microfluidic device that captures circulating tumor cells using DNA 'tentacles' inspired by jellyfish. The device increases flow rates 10 times higher than existing ones, enabling rapid processing of blood samples and potential monitoring of cancer patients.

SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateNov 12, 2012

How the brain controls our habits

A new study from MIT neuroscientists has found that the brain's prefrontal cortex has a small region responsible for controlling which habits are switched on at a given time. The researchers used optogenetics to inhibit this region, allowing them to break and form new habits in rats.

SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateOct 30, 2012

A new glow for electron microscopy

Researchers from MIT have developed a new tag, APEX, that enables high-resolution visualization of proteins in cells using electron microscopy. The APEX tag allows scientists to label and identify specific proteins with unprecedented clarity, resolving open questions regarding protein locations and functions.

SourceMassachusetts Institute of Technology·JournalNature Biotechnology·DateOct 22, 2012

The mathematics of leaf decay

Researchers developed a mathematical model to analyze data from North American forests, finding that warmer climates accelerate leaf decay uniformly, while plant composition determines the range of rates. The study reveals surprising commonality among diverse leaf decay patterns, shedding light on global carbon flux and climate change.

SourceMassachusetts Institute of Technology·JournalJournal of The Royal Society Interface·DateOct 3, 2012