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Massachusetts Institute of Technology


Microfluidic platform gives a clear look at a crucial step in cancer metastasis

Researchers developed a microfluidic device to study cancer cell extravasation, the process by which cells escape blood vessels. The device revealed that most arrested cells are trapped and eventually squeeze through, with their nuclei escaping even earlier than expected. Understanding this process can help identify therapies to preven...

SourceMassachusetts Institute of Technology·JournalIntegrative Biology·DateSep 20, 2013

Study shows projected climate change in West Africa not likely to worsen malaria situation

Researchers at MIT developed a new model of malaria transmission that combines global forecasts with local rainfall data, predicting minimal increase in disease incidence despite projected temperature and rainfall changes. The study aims to provide more accurate predictions for specific variables relevant to society, such as malaria in...

SourceMassachusetts Institute of Technology·JournalEnvironmental Health Perspectives·DateSep 16, 2013

An easier way to control genes

Researchers developed a new method to control genes by targeting transcription, allowing for positive and negative regulation with the same protein. The technique has the potential to enable complex synthetic biology circuits and applications such as disease detection and drug production.

SourceMassachusetts Institute of Technology·JournalACS Synthetic Biology·DateSep 3, 2013

The science of collaboration

Researchers propose a rigorous evidence-based approach to identify what works and doesn't work in collaborations, aiming to improve the efficiency of drug development. Thousands of organizations have come together in over 100 multi-stakeholder collaborations to solve specific problems.

SourceMassachusetts Institute of Technology·JournalScience Translational Medicine·DateAug 28, 2013

How quickly can a bacterium grow?

E. coli bacteria produce at most six times more heat than needed to meet thermodynamic constraints, suggesting they could grow faster and still obey the second law of thermodynamics. This finding has implications for synthetic biology applications and may support the hypothesis that RNA evolved before DNA.

SourceMassachusetts Institute of Technology·JournalThe Journal of Chemical Physics·DateAug 27, 2013

Rethinking investment risk

A paper by MIT economist Alp Simsek suggests that financial innovation does not reduce portfolio risk, but instead raises it by spreading risk through new financial instruments and creating situations where parties hold opposing views. This can lead to increased average portfolio risks as speculative variance becomes dominant.

SourceMassachusetts Institute of Technology·JournalThe Quarterly Journal of Economics·DateAug 26, 2013

Making connections in the eye

Researchers at MIT and Max Planck Institute have mapped the wiring diagram of a tiny patch of mouse retina using a combination of human and artificial intelligence. They identified 950 neurons, including a new type of retinal cell, and classified most of them based on their connections with other neurons.

Surface porosity and wettability are key factors in boiling heat transfer

A team of MIT researchers investigated the factors controlling boiling heat transfer from a surface to a liquid, finding that surface porosity is the most important factor. They developed methodologies for systematically depositing nanoparticles onto surfaces with controlled wettability and porosity, leading to improvements in heat-tra...

SourceMassachusetts Institute of Technology·JournalApplied Physics Letters·DateJul 16, 2013

Phytoplankton social mixers

Research shows that phytoplankton form concentrated patches in turbulent ocean water, counterintuitive to expectations of uniform distribution. This phenomenon, known as 'turbulent un-mixing,' helps phytoplankton find cells of the same species without sensory information.

SourceMassachusetts Institute of Technology·JournalNature Communications·DateJul 15, 2013

A new way to trap light

Researchers at MIT have discovered a new method to trap light that could find applications in lasers, solar cells, and fiber optics. The phenomenon involves destructive interference from waves of opposite phases, blocking certain wavelengths while allowing others to pass through.

Buckling up to turn

Researchers at MIT used high-speed video to record individual marine bacteria and found that a small flexible rod called the hook bucks during forward swims, causing the cell to tumble and reorient. This unusual mechanism helps bacteria navigate toward food in nutrient-sparse ocean waters.

SourceMassachusetts Institute of Technology·JournalNature Physics·DateJul 8, 2013

Innovative MIT study estimates extent to which air pollution in China shortens human lives

A new MIT study estimates that air pollution from coal emissions in China shortens lives by 2.5 billion years, with particulate matter levels over 400 micrograms per cubic meter found in the region. The research uses quasi-experimental methods to project life expectancy losses for 500 million Chinese residents north of the Huai River.

SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateJul 8, 2013