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Ohio State University


Cancerous or harmless? Three genes might tell the tale

A new study by Ohio State University researchers may lead to a test that prevents unnecessary thyroid gland removal in people with follicular adenoma. The study identified three genes, cyclin D2, PCSK2, and PLAB, which show distinct activity levels between noncancerous and cancerous thyroid conditions.

SourceOhio State University·JournalThe Journal of Clinical Endocrinology & Metabolism·DateMar 24, 2005

Nearsighted children may benefit from rigid contact lenses

A three-year study found that rigid gas permeable contact lenses slowed the progression of myopia by nearly 30 percent in nearsighted children. The study, which included over 100 children aged 8-11, showed that RGP lenses altered the shape of the cornea and reduced 'corneal steepening', a condition associated with nearsightedness.

SourceOhio State University·JournalArchives of Ophthalmology·DateDec 13, 2004

New protein identified in development of lung cancer

Researchers at Ohio State University have identified a new protein, Pirh2, that diminishes the activity of p53, a powerful tumor suppressor. Overexpression of Pirh2 was found in 84% of human lung cancers and 93% of mouse tumors, suggesting its potential role in cancer development.

SourceOhio State University·JournalJNCI Journal of the National Cancer Institute·DateNov 16, 2004