Researchers discovered a significant improvement in overall survival for people with Chronic Lymphocytic Leukemia (CLL) after using the antibody rituximab plus fludarabine, increasing progression-free survival by 22% and overall survival by 12%.
Researchers at Ohio State University found that sulfuric acid combines with methanol to form methyl sulfate, which can contribute to cloud formation and trapping of heat. This interaction may have a significant impact on global climate change, but the conditions required for its formation are still not fully understood.
Bacteria use iron oxide to breathe in anaerobic environments, allowing them to degrade toxic waste. Genetic manipulation enables tailored targeting of specific contaminants.
Engineers at Ohio State University have created microscopic finger-like structures that can detect chemicals in the air and may be used for cleaning toxic chemicals, gathering solar energy, or forming fog-free surfaces. The new process involves baking ceramic material with hydrogen gas to create a platform for devices.
Researchers at Ohio State University have created hybrid materials that are virtually defect-free, paving the way for ultra-efficient electronics, solar cells and LEDs. The new technology could lead to faster, less expensive computer chips and bridge the gap between traditional silicon and light-related technologies.
Researchers have viewed an unprecedentedly perfect interface between layers of semiconductor materials germanium and silicon dioxide. This 'atomically sharp' interface could be used to boost the speed of computer chips. The discovery may aid in the design of other devices, including medical implants.
Researchers found that viewers of a scenic parkway video scored lower on a test of frustration and worked almost a minute longer on an unsolvable anagram puzzle compared to those who watched videos of urban driving experiences. The study suggests nature can have a calming effect on drivers.
Researchers at Ohio State University have developed a new muffler design that utilizes glass fiber, reducing auto noise by up to 40 decibels and improving engine performance. The design can be lighter, less prone to corrosion, and help engines work more efficiently.
A study by Ohio State University found that financial stress was a significant contributor to depression in breast cancer patients, even stronger than grief from a loved one. Researchers analyzed data from 210 women with stage II or III breast cancer and found a strong link between money-related stress and depressive symptoms.
Researchers developed MVAPICH, a software that connects traditional supercomputing software with InfiniBand technology, enabling faster data flow. The innovation allows scientists to study climate change and other complex phenomena more efficiently.
After a spinal cord injury, the body's natural response can lead to larger, more debilitating lesions in the spinal cord. Researchers found that glutamate and tumor necrosis factor-alpha (TNFa) over-stimulation cause secondary damage to white matter tissue and destroy oligodendrocytes, which protect axons.
Researchers found that blocking blood flow to the brain, like mini-strokes, can impair mental function by reducing nerve cell fibers that use acetylcholine. This study provides insight into the effects of cerebral blood flow disruption on cognitive decline in dementia, highlighting the importance of maintaining healthy blood vessels.
The study found that oxidation damages certain kinds of messenger RNA, leading to abnormal protein processing and neuronal death. Researchers discovered specific types of mRNA susceptible to oxidative damage, which may contribute to the onset and progression of Alzheimer's disease.
Researchers found decreases in genes producing growth hormone and prolactin, key to development and immune system function, in aged mice compared to young mice. This suggests specific genetic changes in the cerebellum area of the brain may contribute to loss of motor control and balance with age.
Researchers have found significant decreases in growth hormone and prolactin gene expression in the cerebellum of aged mice, suggesting a possible link between these hormones and age-related declines in motor control and balance. Further study is needed to understand the role of genetic pathways in aging.
A study by Ohio State University researchers found that participants were more likely to incorrectly identify a similar image as part of the original set, even though it was not present. This suggests that visual false memories can be induced using context, challenging our perceptions and memory recall.
Researchers hope that ice cores and ancient plants retrieved from glaciers in the Peruvian Andes may contain clues about a mysterious global climate change that occurred over 5,000 years ago. The cores are expected to provide a critical piece of the puzzle needed to understand climate variability in the region.
Scientists at Ohio State University have found evidence of silk-spinning structures on the fossilized body of an ancient arachnid, called Aphantomartus pustulatus. The finding suggests that silk-spinning has been around for a long time and could provide insights into the early evolution of arachnids and life on land.
A new computer model developed at Ohio State University provides a detailed understanding of how municipal wells in Woburn, Massachusetts, came to be contaminated with toxic chemicals. The results suggest that the contaminants likely originated from industrial properties and flowed into the nearby Aberjona River, raising concerns about...
Researchers from Ohio State University discovered that Blood Falls is the last remnant of an ancient salt-water lake, formed when sea levels were higher. The lake probably existed 5 million years ago, and its remains are being slowly pushed out by the glacier.
Researchers at Ohio State University Comprehensive Cancer Center found that a diet rich in whole tomatoes, but not supplements, was associated with longer survival rates and reduced risk of prostate cancer. The study also showed that energy restriction did not offer additional benefits over a balanced diet.
A new class of compounds called CBR703 series inhibit RNA polymerase, a key enzyme in gene expression, and hinder the ability of bacteria to perform crucial catalytic functions. The compounds render RNA polymerase useless by binding to a specific place on the enzyme.
The study reveals that retroviral protein p12 stimulates the growth and proliferation of immune cells known as T lymphocytes by producing interleukin 2 (IL-2). This finding supports the view that HTLV-1 virus replicates mainly by causing infected cells to divide and proliferate.
A recent study published in the Journal of Planning Education and Research found that suburban residents felt a close sense of community with their neighbors. Despite criticisms that suburbs are cold and sterile, the study refuted these claims by showing that both traditional and suburban neighborhoods can foster strong community bonds.
A survey of 1,500 Kuwaiti citizens found that support for democracy grew substantially during the four years covered in the study. Kuwaitis also became less interested in trade alliances with the West and paid little attention to Western media.
A study by Ohio State University researchers found that even mild depression in caregivers can lead to increased inflammation, which is associated with various age-related illnesses. Chronic inflammation has been linked to declines in physical function and an increased risk of mortality.
Researchers at Ohio State University have developed a new diode that can replace some circuits on a typical chip, simplifying design without compromising performance. The diode conducts 150,000 amps per square centimeter, ideal for low-power devices and medical applications
The study found that methylation levels in a specific gene can predict the seriousness of breast cancer. High levels of promoter methylation correlate with an altered structure of the gene, resulting in a tightly closed DNA configuration that prevents gene activation.
Girls developing early are more likely to be involved in delinquency due to their relationships with friends, who may be already involved in delinquent behaviors. Dating also plays a significant role, as early-developing girls are more likely to have romantic relationships and engage in minor delinquencies.
A new report warns that the US air transportation system is in peril due to a lack of coordination among stakeholders. The report calls for a focused national leadership and strategic vision to enable the airline industry to meet increasing travel demand.
A study by Ohio State University's Lisa Keister found that people who regularly attend religious services tend to be more wealthy than those who don't. The effect of religion is robust even after considering other factors such as inheritances and education, suggesting that faith influences spending and saving strategies.
Researchers at Ohio State University discovered a series of phase transitions that cause silicon crystals to round their edges as they reach thermal equilibrium. This finding has implications for the manufacturing of tiny electronic components, such as wires and semiconductors, which could be designed with specific patterns.
Researchers found that oxygen-sensitive genes in cardiac fibroblasts transform into myofibroblasts, critical for wound healing after a heart attack. The newly formed myofibroblasts help replace damaged tissue.
Researchers found that pollutants like lindane and hexachlorobenzene (HCB) behave differently in the presence of organic matter and sunlight, with HCB degrading at higher rates. The study suggests that pollutants can have varying effects on local ecosystems and human health.
Researchers at Ohio State University discovered that by coating a nickel mesh with molecules of fat, they can control the amount of light passing through using heat. This phenomenon, known as surface plasmons, allows for precise control over light transmission, enabling new applications in optoelectronics and lab tests.
Ohio State University researchers developed a three-tiered biowarfare agent detection system for Navy ships, using portable hand-held assays and polymerase chain reaction (PCR) tests. This allows for quick detection of suspected biological agents, enabling medical personnel to provide timely treatment.
The Tensor Contraction Engine (TCE) is a new software that automatically generates computer code for complex molecules, reducing the workload for researchers. By generating efficient parallel programs, TCE can save time and computational resources for projects in computational chemistry and physics.
Researchers found endostatin treatment reduced invasive head and neck cancer cells by half and their migratory capabilities by one-quarter. The study suggests an implanted drug delivery system could provide sustained therapeutic drug levels directly to tumors.
Researchers found that musicians played at a tempo closer to fast music when listened to before playing, while speakers read faster or slower after hearing a recording's speaking rate. Both groups unconsciously coordinate timing to find a mutually agreeable tempo.
Researchers at Ohio State University found that endostatin can stop Kaposi's sarcoma cells from growing new blood vessels and migrating through the body. The study suggests a controlled release of endostatin could be an effective treatment option for patients with KS.
A study by Ohio State University found that students taking a psychology-based study skills program had higher grade point averages and were more likely to return for their next year of college. The course used well-founded psychological principles to teach students how to put motivation and learning techniques into practice.
A study of elite male athletes found that about one in five believed they weren't sufficiently muscular and wanted to gain weight. The findings showed that 17.5% of athletes in lean sports exhibited symptoms of eating disorders compared to 9.2% in non-lean sports.
A study by Ohio State University researchers found that children with mild inflammatory bowel disease (IBD) are more likely to experience behavioral and emotional problems, including being withdrawn or anxious. The study also showed a link between the severity of IBD and social functioning.
A new study by Ohio State University researchers found that eight autistic children who participated in the Early Intensive Behavioral Intervention (EIBI) program showed significant improvements in IQ scores and adaptive behavior. Six of the children achieved average IQ scores, while two improved to mild mental retardation.
Research suggests that early hominids lived in a more cooperative society than previously thought, with minimal sexual dimorphism and cooperating male behaviors. This challenges the idea of fierce competition among primates and instead reveals a social structure similar to modern humans and chimpanzees.
A new study finds that NASA's Space Interferometry Mission (SIM) can detect habitable planets near significantly more massive stars than the sun. The satellite will use interferometry to measure the position of stars and detect tiny wobbles caused by orbiting planets.
A recent study found that 15% of African-American youths at risk of dropping out of school reported carrying a gun, with regular carriers more likely to be involved in selling drugs or fighting. The study suggests that carrying a gun may indicate a more serious pattern of behavior, rather than just another risk factor.
A study of nearly 81,000 women found that regular use of ibuprofen reduced breast cancer risk by 28%, while aspirin use reduced it by 22%. Both NSAIDs showed a significant effect in reducing the incidence of breast cancer, especially among high-risk groups.
The Public-Sector Intellectual Property Resource for Agriculture (PIPRA) is a roadmap guiding public research institutions in managing and sharing intellectual property. PIPRA aims to facilitate the commercialization of new crops by allowing multiple institutions to hold parts of intellectual property rights.
A study of 778 Ohio State University students found that nearly two-thirds (64%) were in the precontemplation stage, which is associated with increased heavy drinking. In contrast, students who had cut back on their intake reported perceiving more risks and fewer benefits associated with alcohol use.