A recent study published in PLOS Pathogens found that the COVID-19 Delta variant may have a reduced ability to be neutralized by vaccines. The researchers analyzed serum samples from vaccinated individuals and found that the Delta variant was more effective at evading vaccine-induced immunity than other variants, such as Beta and Alpha.
Researchers have identified pigtailed macaques as a suitable animal model for studying two emerging tick-borne hemorrhagic viruses, Kyasanur Forest disease and Alkhurma hemorrhagic disease. The study found that infected macaques exhibited symptoms similar to those in humans, including loss of appetite, dehydration, and hemorrhaging.
Researchers found 2.4 times the rate of arbovirosis as originally reported, including coinfections, suggesting underestimation of the incidence of the three viruses. The study enriches epidemiological information on these arboviruses, which can help improve estimates of burden and resource allocation.
SourcePLOS·JournalPLOS Neglected Tropical Diseases·TypeExperimental study·DateDec 2, 2021
A recent study found associations between air and water pollutants and changes in the human sex ratio at birth. Pollutants such as PCBs, iron, lead, and chromium were linked to an increased or decreased ratio of baby boys to girls.
SourcePLOS·JournalPLOS Computational Biology·TypeComputational simulation/modeling·DateDec 2, 2021
Researchers found that increased physical activity reduced mortality risk in all groups, but health benefits plateaued in healthy individuals and those with cardiovascular risk factors. In contrast, cardiovascular disease patients showed no further benefit beyond a certain volume of physical activity.
Researchers have developed a comprehensive Lyme disease dashboard to define hotspots and map the disease across the US and Canada. The dashboard provides valuable insights for public health awareness and research collaboration.
A randomized field experiment with 1,143 students aged 9-16 found that depleted self-control from a previous demanding task increases cheating in tests. The study suggests that exhaustion can lead to a greater temptation to cheat.
A new COVID-19 mobile robot detects social distancing breaches in crowds and encourages people to move apart using a novel system that employs Deep Reinforcement Learning and Frozone algorithm. The robot also incorporates a thermal camera for contact-tracing efforts, ensuring privacy protection and de-identification.
SourcePLOS·JournalPLOS ONE·TypeComputational simulation/modeling·DateDec 1, 2021
A recent study found that 19.9% of trans feminine individuals and 2.56% of trans masculine individuals were HIV positive, highlighting the need for targeted prevention efforts. The researchers called for increased focus on this population's unique needs.
A study published in PLOS Medicine found that pregnant women with COVID-19 are more likely to experience complications during pregnancy and childbirth, including ICU admission, preeclampsia, and cesarean section. Vaccination may help protect these women, especially those at higher risk of severe COVID-19 infections.
Forced family separation on the US-Mexico border led to a high incidence of PTSD, depressive, and anxiety disorders in asylum-seeking children and parents. Reunification did not alleviate these symptoms, highlighting the need for continued support and intervention.
A new study published in PLOS Global Public Health has mapped the distance to HIV care services in sub-Saharan Africa, highlighting that 7 million people live more than 10 minutes away and 3 million people live more than 30 minutes away. The research aims to develop cost-effective policies for HIV interventions in underserved areas.
SourcePLOS·JournalPLOS ONE·TypeComputational simulation/modeling·DateNov 24, 2021
A new statistical analysis supports the notion that COVID-19 became more lethal in the UK in late 2020, with increased lethality attributed to factors beyond just the alpha variant of the virus. The study used Bayesian inference to draw stronger conclusions from weekly data on cases and deaths.
SourcePLOS·JournalPLOS ONE·TypeComputational simulation/modeling·DateNov 24, 2021
A new study found that 20.2% of participants reported avoiding healthcare during the pandemic, with those who are most likely to be affected being older individuals and those with low perceived health. The study calls for targeted public education to urge vulnerable citizens to seek medical attention.
A recent study published in PLOS Biology found evidence of editorial bias and nepotism in some biomedical journals, where a few authors, often on the editorial board, dominate publications and receive preferential treatment.
A new analysis found that non-vegetarian diets result in higher greenhouse gas emissions than vegetarian diets, while a diet rich in nutrients and low in saturated fats can significantly reduce emissions. The study suggests small changes, such as cutting out sweets or switching brands, can make big environmental gains.
A study published in PLOS Computational Biology found that rodents have a greater diversity and accelerated rate of evolution in the ACE2 receptors used by SARS viruses. This suggests that some rodent species may be asymptomatic carriers of SARS-like coronaviruses, potentially leading to new pathogen transmission to humans.
SourcePLOS·JournalPLOS Computational Biology·TypeComputational simulation/modeling·DateNov 18, 2021
A new study reveals that glial cells in the heart play a critical role in regulating heart rate and rhythm, as well as driving its development in the embryo. The discovery suggests that glia may also be important in other organs.
The CDC's four-tiered vaccine prioritization strategy outperformed most approaches in reducing deaths and cases, while some optimizations could improve outcomes. The study found that prioritizing healthcare workers and individuals under 16 was optimal, but strategies focusing on comorbidities were also effective.
SourcePLOS·JournalPLOS ONE·TypeComputational simulation/modeling·DateNov 17, 2021
Young veterans with mTBI experience premature cognitive decline in specific domains, matching elder normative scores and early-stage Parkinson's patients. The study highlights the significant negative impact of mTBI on cognitive function compared to healthy non-veterans.
Research in Japan found a link between financial knowledge, age, and gender, suggesting potential policy targets to improve financial health. While men had higher financial literacy, women reported more sound financial behaviors, indicating that policies may need to focus on supporting women's financial decision-making.
Children of depressed parents are more likely to develop depression and poor academic performance, according to a new study published in PLOS ONE. The study found that both maternal and paternal depression have significant effects on children's mental health and educational outcomes.
A study of 8-12 year olds reveals that media multitasking is associated with worse mental health outcomes, while videogaming shows a positive correlation. The research highlights the importance of balancing screen time with other activities for children's overall well-being.
Researchers use game theory and economics to steer evolution in a better direction, identifying conditions for improved outcomes through policy changes and coordination. The study provides a mathematical formula to determine when evolution managers will have sufficient incentive to steward biological resources.
SourcePLOS·JournalPLOS Biology·TypeComputational simulation/modeling·DateNov 16, 2021
A study of healthy individuals aged 50-74 found that coffee and tea consumption was associated with reduced rates of stroke and dementia. People who drank 2-3 cups of coffee and 2-3 cups of tea daily had a 32% lower risk of stroke and a 28% lower risk of dementia compared to those who consumed none.
A global study of nearly half a million students found that repeated grades increase the risk of bullying victimization. Girls who repeated grades faced higher risks of being bullied in various ways, including being made fun of and having possessions taken away.
A new study found that tumors with one mutant copy of the PIK3CA gene tend to have lower PI3K activity, while those with two or more copies often have higher PIK3α activity, leading to more aggressive tumors and poorer prognosis. The research also discovered a counterintuitive relationship between PI3K mutations, PI3K activity, and ste...
SourcePLOS·JournalPLOS Genetics·TypeComputational simulation/modeling·DateNov 11, 2021
Researchers have identified specific skin microbiome bacteria and their pathways as contributing to ageing skin. The study, published in PLOS ONE, used a novel approach to chart host-microbe co-metabolism in skin aging.
A new study published in PLOS ONE found that over half of surveyed healthcare workers reported PTSD symptoms during the COVID-19 pandemic, regardless of previous SARS experience. Healthcare workers with prior SARS experience showed lower scores of PTSD and depression, but this effect disappeared after correcting for other factors.
A new study published in PLOS ONE found that homeschooled adolescents tend to exhibit higher levels of character strength and engage in healthier behaviors, such as volunteering and religious service attendance. However, they are less likely to pursue higher education compared to their public school counterparts.
The world's largest ammonite species, Parapuzosia seppenradensis, reached diameters of 1.5-1.8 meters around 80 million years ago. This evolution likely helped the species evade predation and survive in its environment.
A study of four US states finds that Black people are more likely to be nonfatally shot and injured by police, with disparities greater than seen for fatal shootings. The research highlights the need for comprehensive data on police shootings to draw reliable conclusions about racial disparities.
A new machine learning-based approach enhances student engagement in online environments. The algorithm detects when students disengage, prompting interventions to improve learning outcomes.
In an experiment, pet cats were found to track their owner's location using the sound of their voice. Researchers discovered that cats can mentally map the location of their owners based on the unique acoustic characteristics of their voices.
A systematic review of 28 studies identified 13 themes related to COVID-19 vaccination status in older, ethnic minority individuals. Factors facilitating access included vaccination reminders from healthcare providers, while misinformation and personal beliefs were barriers to uptake.
A study found that female zebra finches are choosy but flexible in their mating preferences, allowing them to avoid fitness costs. The researchers discovered that these 'wallflowers' can still produce successful fledglings by sneaking eggs into other birds' nests.
Researchers identified 23 genes contributing to congenital heart disease, including 12 previously unknown, using a new algorithm called M-DATA. This method combines genetic data from people with related conditions, increasing the power to identify risk factors and potentially leading to improved treatments.
SourcePLOS·JournalPLOS Genetics·TypeComputational simulation/modeling·DateNov 4, 2021
A new study identifies four novel obesity genes and predicts a fifth, using a platform of fat fruit flies. The research found that these genes are involved in a neuronal signaling pathway that increases fat levels.
A statistical modeling approach highlights predictive importance of local climate and human activity in determining wildfire probabilities. The analysis uncovered key roles for climate, human activity, fire history, and short-term climate variations in fire-prone regions.
SourcePLOS·JournalPLOS ONE·TypeComputational simulation/modeling·DateNov 3, 2021
A new study from Italy found that students with high conscientiousness and openness tend to perform better academically. The research suggests that personality traits play a significant role in university success.
A prospective-longitudinal study found that pregnant women with lower emotional stability and personality traits tend to have worse subjective birth experiences. Unexpected events like Caesareans can exacerbate these negative experiences.
A new machine learning-based algorithm has been developed to identify adolescents who have experienced suicidal thoughts and behavior. The algorithm, applied to a large dataset of survey responses from over 179,000 high school students in Utah, shows high accuracy in predicting individual adolescents at risk.
SourcePLOS·JournalPLOS ONE·TypeComputational simulation/modeling·DateNov 3, 2021
A new analysis reveals that plankton-eating fish play a central role in driving local spikes of extreme biological productivity in tropical coral reefs. These 'sweet spots' concentrate abundant fish production, making them optimal for fishing. The study's findings hold significance for the future of tropical reef fisheries as coral ree...
Researchers found that around 5% of patients with type 2 diabetes in Scotland are in remission, suggesting a need for updated guidelines to support clinicians. Individuals in remission tend to be older and have lower blood sugar levels at diagnosis, and often achieve remission after weight loss since their diagnosis
A new study published in PLOS Medicine found that people who abstain from alcohol do not necessarily have a shorter survival time than those who consume low to moderate amounts. The study, which analyzed data from over 4,000 German adults, suggests that factors such as previous substance abuse or poor health are more significant predic...
A new model has been developed to help archeologists uncover new Pleistocene sites in Cyprus, revealing more evidence of historic hunter-gatherer activity on the island. The study suggests that there may have been more human activity on Eastern Mediterranean islands during the last ice age than previously thought.
US emergency department spending grew to $136.6 billion in 2016, with road injuries and falls accounting for the highest amount of ED spending. The study found that ED spending per visit increased at an annualized rate of 3.4% over the decade.
The study suggests that unsustainable wood harvesting by the Ancestral Puebloans occurred around 2000 years ago in Chaco Canyon, USA. This practice had significant ecosystem impacts, which are still being felt today.
A 51-country survey reveals that people who feel invincible to COVID-19 are less likely to get vaccinated and believe in the importance of individual actions. The study suggests that messaging emphasizing collective action is crucial in individualistic cultures.
A study published in PLOS ONE found that students who felt their university failed them during the pandemic were more likely to experience trauma symptoms. The authors analyzed data from a large group of undergraduate students and discovered a significant association between institutional betrayal and trauma symptoms.