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Researchers discover genetic cause of megaesophagus in dogs

A new study by Clemson University researchers identifies a genetic variant linked to congenital idiopathic megaesophagus (CIM) in German shepherd dogs. The discovery enables the development of a genetic test with 75% accuracy, allowing breeders to reduce disease incidence while preserving genetic diversity.

SourcePLOS·JournalPLOS Genetics·TypeExperimental study·DateMar 10, 2022

Hugging a “breathing” cushion to ease anxiety

A new, touch-based device has been developed to ease anxiety in students by mechanically simulating breathing. The 'breathing' cushion was found to be equally effective at reducing anxiety as guided meditation in a study of 129 volunteers.

SourcePLOS·JournalPLOS ONE·TypeExperimental study·DateMar 9, 2022

Music combined with auditory beat stimulation may reduce anxiety for some

A new study found that music and auditory beat stimulation can significantly reduce state anxiety in people with moderate trait anxiety. The treatment was more effective than music alone or pink noise for reducing somatic anxiety, while music alone was more effective for reducing cognitive state anxiety.

SourcePLOS·JournalPLOS ONE·TypeRandomized controlled/clinical trial·DateMar 9, 2022

Office buildings with infrequent water use may have poor water quality

A study published in PLOS Water found that office buildings with low-consumption plumbing may experience chemical and microbiological safety issues due to weekend stagnation. The research highlights the need for regular water testing in commercial buildings, even those designed as 'green' to reduce water consumption.

SourcePLOS·JournalPLOS Water·TypeObservational study·DateMar 9, 2022

Seeing is believing when it comes to health risk and behavior change

A meta-analysis of 21 randomized controlled trials found that visualized personalized risk information can reduce smoking, improve diet and physical activity, and increase oral hygiene behaviors. This suggests that medical imaging technologies could be used to motivate behavior change and reduce disease risks.

SourcePLOS·JournalPLOS Medicine·TypeMeta-analysis·DateMar 3, 2022

Lipid profiling can predict risk of diabetes, cardiovascular disease decades before onset

A new study reveals that simultaneous measurement of dozens of types of fats in the blood can predict the risk of developing type 2 diabetes and cardiovascular disease years in advance. The researchers found that individuals with a certain lipid profile are at increased risk, while those with a different profile have lower risk. This d...

SourcePLOS·JournalPLOS Biology·TypeObservational study·DateMar 3, 2022

Changing your mind based on information, or simply to conform? Brain activity differentiates between types of social influence

A study published in PLOS Biology reveals distinct brain regions associated with informational and normative social influence. The researchers found that the dorsal anterior cingulate cortex (dACC) is active when people conform to information, while normative influence is linked to stronger connections between dACC and other social pro...

SourcePLOS·JournalPLOS Biology·TypeExperimental study·DateMar 3, 2022

In one cleft surgery NGO mission trip in Morocco, an all-female healthcare team empowered volunteers to seek further mentorship as well as to mentor others

In a cleft surgery NGO mission trip in Morocco, an all-female healthcare team empowered volunteers to seek further mentorship and to mentor others. The team's influence on female healthcare professionals was found to be significant, promoting a supportive environment for growth and development.

SourcePLOS·JournalPLOS Global Public Health·DateMar 2, 2022

Anti-tumor drug promotes weight loss in mice

A new study found that an anti-tumor drug, camptothecin, can activate a natural hunger-suppressing pathway in mice, leading to significant weight loss. The mechanism involves the elevation of growth differentiation factor 15 (GDF15), which suppresses food intake and reduces body weight.

SourcePLOS·JournalPLOS Biology·TypeExperimental study·DateFeb 24, 2022

Exploring Indian genetic heritage in present-day Thailand

A new genetic study found evidence of South Asian genetic admixture in several mainland Southeast Asian populations influenced by Indian culture. The researchers also discovered close genetic links between languages from different families, supporting an earlier hypothesis about their common origin.

SourcePLOS·JournalPLOS Genetics·TypeObservational study·DateFeb 17, 2022

India may have experienced 3.2-3.7 million COVID-19 deaths to date, one of the highest death tolls, according to new model using alternative data sources to address underreporting

A new model estimates India's actual COVID-19 death toll could be as high as 3.2-3.7 million, surpassing other reported figures. This revised estimate aims to address the issue of underreporting and provides a more accurate representation of the pandemic's impact on India.

SourcePLOS·JournalPLOS ONE·DateFeb 16, 2022

Orangutans instinctively use hammers to strike and sharp stones to cut

In a study published in PLOS ONE, researchers found that untrained captive orangutans can complete two major steps in making and using stone tools: striking rocks together and cutting using sharp stones. This suggests that the use of stone tools may have existed in our last common ancestor with orangutans 13 million years ago.

SourcePLOS·JournalPLOS ONE·TypeExperimental study·DateFeb 16, 2022

Clean-energy discourse from energy giants not reflected in investments

A new study analyzed the clean energy discourse of four large oil and gas companies, finding that their business actions and investments do not align with their climate change pledges. Despite increased use of keywords like 'climate' and 'transition', the companies have made limited progress towards decarbonization.

SourcePLOS·JournalPLOS ONE·TypeObservational study·DateFeb 16, 2022

Human microbiome research excludes developing world

A new study found that almost half of all publicly available human microbiome samples come from the US, despite it representing only 4.3% of global population. This raises concerns about the applicability of future microbiome-based medical treatments to countries with limited resources.

SourcePLOS·JournalPLOS Biology·TypeObservational study·DateFeb 15, 2022

Study of U.S. employees defines the odds of COVID-19 reinfection

A new US-based study published in PLOS Biology found that most people who have had COVID-19 are protected against reinfection for at least six months. The research analyzed data from 4,441 SpaceX employees and estimated an odds ratio of 0.14 to 0.28 for reinfection depending on the time period considered.

SourcePLOS·JournalPLOS Biology·TypeObservational study·DateFeb 10, 2022

Trust in science rose in Germany after onset of COVID-19 pandemic

Public trust in science increased in Germany during the COVID-19 pandemic, with stronger increases among educated individuals and those supporting the left-wing party. Despite this rise, public trust declined slightly by November 2020, highlighting the need for effective communication strategies to maintain trust

SourcePLOS·JournalPLOS ONE·TypeSurvey·DateFeb 9, 2022

Perspectives of patients in clinical trials often not considered

Many pragmatic trials fail to collect patient-reported data on experience, burden of disease, and quality of life. Despite this, the authors suggest that including patient-reported outcomes can provide valuable insights into patient well-being. The study urges researchers to prioritize patient-centered approaches in clinical trials.

SourcePLOS·JournalPLOS Medicine·TypeObservational study·DateFeb 8, 2022

Changing your diet could add up to a decade to life expectancy, study finds

A new model estimates the impact of dietary changes on life expectancy, suggesting that adopting an optimized diet rich in legumes, whole grains, and nuts can increase lifespan by over a decade. For young adults, this could add up to 10-13 years, while older individuals may still experience significant gains.

SourcePLOS·JournalPLOS Medicine·TypeComputational simulation/modeling·DateFeb 8, 2022