The trial, led by Saint Louis University, is a phase I trial investigating the safety and immune response of EP HIV-1090 vaccine candidate. Participants will receive the vaccine or placebo over 18 months, with observations to assess its potential effectiveness against HIV.
Researchers found that adults who received smallpox vaccinations as children showed fewer adverse reactions to diluted vaccine doses compared to those who never received the vaccine. The study's results have implications for potential future biological attacks and suggest that vaccine stocks may be more sustainable.
Researchers at Saint Louis University found that daily injections of growth hormone helped obese patients lose an average of five pounds. The weight loss was primarily due to the reduction of body fat, particularly in the abdominal area.
A study by Saint Louis University School of Public Health found that parents who received nutrition information ate more fruits and vegetables, consumed less fat, and had a greater impact on their children's health. The High 5, Low Fat Program aims to deliver consistent messages to young families, promoting healthy eating habits.
A six-year study found that lung volume reduction surgery improves quality of life and survival rates for patients with upper lobe emphysema who are unable to exercise. The procedure did not show overall survival benefits, but identifying non-beneficial candidates is crucial.
Researchers at Saint Louis University found that injecting human umbilical cord blood cells into rats after a stroke improved sensorimotor function. The treatment may provide a potential source for restoring neuronal function after a stroke.
A new interactive CD-ROM guides parent educators on teaching adults and children about healthy eating habits, which are linked to reduced cancer risk. The program aims to increase fruit and veggie consumption among African-Americans, who face higher cancer risks.
A Saint Louis University study found that fat mice get fatter as they age due to a blood-brain barrier defect, while skinny ones remain the same. The researchers propose identifying substances that impair leptin transport to develop new obesity treatments.
Researchers found that obese baboons had normal leptin levels, indicating that high cholesterol and obesity are triggered by different mechanisms. The study's findings suggest that humans can get away with indulging in unhealthy habits without suffering severe health consequences.
A new study links overweight individuals to poor community environments with crime and safety concerns. Missouri residents who perceived their neighborhoods as unsafe were more likely to be overweight.
African-American infants are disproportionately affected by sudden infant death syndrome (SIDS) due to sleeping on non-crib surfaces or sharing a bed with adults. The study highlights the need for public awareness campaigns to address this racial disparity and promotes the use of cribs as the only safe places for sleeping babies.
A breakthrough discovery by Saint Louis University researchers reveals how the protein Bre1 functions in normal cells, shedding light on its role in cancer development. The study suggests that understanding this protein's regulation of gene expression could lead to new ways to block cancer-causing pathways.
A new set of guidelines, known as Clinical Glidepaths, aims to improve treatment decisions for older adults by considering individual probabilities of life expectancy and function. The 24 paths cover various common problems faced by elderly patients, allowing clinicians to tailor care to each patient's unique needs.
A large clinical trial will be conducted at 16 US sites, with Saint Louis University leading as the national coordinating site. The study aims to prevent genital herpes in women using an investigational vaccine.
A new study published in Pediatrics recommends screening for medical problems and addressing treatment barriers when treating overweight children. Healthcare providers face challenges such as parental resistance, patient lack of motivation, and insufficient support services, hindering effective treatment.
A team led by Tim Kusky has discovered the world's first large intact pieces of oceanic mantle from the planet's earliest period, dating back 2.5 billion years. The findings suggest that plate tectonics began shifting more than 500 million years earlier than previously believed.
A pioneering neurosurgeon has successfully implanted an artificial vision system in eight blind patients, enabling them to drive cars and navigate their surroundings. The device, developed by the Dobelle Institute, stimulates the brain's visual cortex to create a semblance of sight.
The Saint Louis University School of Public Health has launched High 5-Kids, a four-year program aiming to educate parents on normal childhood eating patterns. The initiative seeks to encourage healthy eating habits among preschool children, aged 3-5 years, and promote a balanced diet to prevent obesity and cancer.
Researchers at Saint Louis University School of Medicine found that small doses of botulinum toxin Type A effectively relaxed muscles involved in triggering tension headaches, resulting in reduced frequency and intensity for most patients. The injections were also easier to control symptoms.
A recent study found that physicians often avoid discussing spirituality with patients due to concerns about opening Pandora's box. Despite 78% believing in a connection between religion and health, only 8% have discussions with patients on spiritual topics.
Dr. Duane Grandgenett receives nearly a million dollars in grants to study ways of inhibiting HIV replication in humans. He aims to develop an HIV inhibitor targeting the integrase protein, which plays a crucial role in the virus's survival.