A new study by UCLA researchers found that Rh-incompatible mothers are more than twice as likely to have children with schizophrenia. The study mapped genetic data from 181 Finnish families and discovered a significant link between the RHD gene and schizophrenia risk.
Researchers are studying the effects of Bacopa monniera on cognitive function in people over 65. The 50-participant clinical trial aims to maximize cognitive function and assess the supplement's impact on short-term memory, attention, and reaction time.
The Rice Connexions program is expanding its offerings with new software tools and partnerships, making high-quality educational content freely available worldwide. The project aims to empower diverse cultural communities and break down barriers between academic disciplines through a collaborative approach to teaching materials.
A large clinical trial will be conducted at 16 US sites, with Saint Louis University leading as the national coordinating site. The study aims to prevent genital herpes in women using an investigational vaccine.
Researchers found that living in a female-headed family at age 14, having low self-esteem, and poor verbal/math skills predicted depressive symptoms in young adulthood. The study also highlighted the need to disentangle women's marital status from their age at first birth.
Case Western Reserve University's ANSMET team will conduct six-week Antarctic expedition to recover rare Martian meteorites, expanding planetary science research capabilities.
Virginia Tech researchers are working on ways to protect battery-operated computers and wireless devices from hacking attempts that can drain their batteries. The project aims to develop built-in measures to prevent such attacks, which could become a major concern for the wireless industry.
Patients who received outpatient cardiology care had lower two-year mortality rates compared to those without. Concurrent care by cardiologists and primary care physicians may improve outcomes.
A sub-analysis of the ASSENT-3 trial data found that anti-coagulation drugs have different effects in patients with diabetes after a heart attack. Enoxaparin was recommended for acute heart attack patients with diabetes due to its lower risk of death and refractory chest pain compared to abciximab.
A major herpes vaccine trial is underway for women to prevent genital herpes, with over 70% of HSV-1 and HSV-2 negative women showing protection against the disease. The trial aims to recruit thousands of HSV-negative women to test the efficacy of a subunit vaccine containing a piece of the virus outer coat.
The lack of harmonization in European clinical trial regulations is jeopardizing progress in state-of-the-art treatment strategies, denying patients the benefits of advances. This is particularly concerning in complex fields like cancer research, where multi-disciplinary and multi-modality treatment is required.
A new definition of transient ischemic attack (TIA) is proposed to improve stroke treatment, focusing on brain injury rather than arbitrary time limits. The revised definition aims to increase the use of clot-busting medication and reduce delays in treatment.
Research reveals that foreign-born nursing home aides face on-the-job racism, while African-American aides are less likely to experience it. The study also highlights the prevalence of racist attitudes among nursing home residents, which can impact staff behavior.
Scientists are using species profiling to help prevent invasive fish introductions into the Great Lakes and other waterways. A new method has been discovered to detect skin diseases in fish using a fluorescent dye.
Researchers found dramatic gray matter loss in the brains of men with sleep apnea, primarily in regions controlling speech production, movement, and emotion. The severity of brain damage correlated directly with disorder severity, suggesting that early brain wiring abnormalities may contribute to sleep apnea onset.
A pioneering study found that time urgency and impatience during young adulthood are associated with increased risk of developing hypertension years later. The strongest link was seen among white men, who were more than three times as likely to develop high blood pressure as those in lower TUI groups.
Researchers studied 5069 patients and found that African Americans had lower exercise capacity despite higher rates of obesity. The study highlights the importance of weight reduction and increased physical fitness for preventing cardiovascular disease in African Americans.
A study by Purdue economist William Masters found that African mothers are willing to pay a premium of 30% for infant food with guaranteed quality and safety information. This could lead to reduced child malnutrition rates if generic options were made available, saving up to 6 million lives annually.
A study by researchers at the H.Lee Moffitt Cancer Center has identified the ERCC1 gene as a potentially clinically useful independent marker for lung cancer. Patients with high levels of ERCC1 are more likely to survive after surgery and may benefit from platinum-based chemotherapy, while those with low levels have a poorer prognosis.
Duke University Medical Center researchers found that a new drug combination, combining eptifibatide and tenecteplase, speeds up and sustains restored blood flow to the heart. The study showed significant improvements in ECG readings, with patients receiving the combination therapy returning to stable levels within 55 minutes.
A study of 39 hepatitis C patients found that 33% developed interferon-induced major depression, but 84% improved with antidepressant treatment. The research challenges the common practice of discontinuing interferon therapy for depressed patients.
A study on atorvastatin found patients experienced quality of life improvements, but primary endpoints were not met. Peripheral arterial disease affects millions worldwide, causing leg pain and reduced blood supply.
Researchers found that inhibiting PDGF signalling increases tumour uptake of cytotoxic drugs without increasing toxicity. Combination therapies with Glivec and other drugs induced better anti-tumour effects in animal models, suggesting a new strategy for improving drug treatment for cancer patients.
Craighead's research focuses on developing chip-based chemical and biochemical analysis systems with high-speed capabilities. He aims to create rapid medical diagnosis or environmental monitoring tools using microfluidic systems and engineered nanostructures.
A study of ICD patients found a significant increase in dangerous irregular heartbeats after a terrorist attack, highlighting the impact of stress on the heart. The rate of ICD discharges remained elevated for a month following the attack.
The study aims to understand the burden of neurological disease in people living with HIV and inform effective management strategies. A cross-sectional study will assess prevalence and features of neurocognitive-behavioral complications, while a subset of patients will be followed over time to monitor health status.
A Phase I study of the novel anti-angiogenic drug SU011248 showed promising results in patients with advanced cancers that had failed to respond to other therapies. The drug demonstrated activity in a range of tumour types, including renal and gastrointestinal cancers, but did not show efficacy against brain metastases.
Researchers identified key genes and metabolic pathways to differentiate the bacterium from related species, shedding light on its unique biology and slow growth rate.