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University of Michigan


Scientists find new way to manipulate DNA

Researchers developed a new formula to design flows that break polymers into specific lengths or withstand certain flows, with potential implications for industries like shipping and oil. This discovery also enables more precise control over the length of DNA strands in genome sequencing.

SourceUniversity of Michigan·JournalProceedings of the National Academy of Sciences·DateNov 15, 2006

Fossil is missing link in elephant lineage

A pig-sized, tusked creature discovered in Eritrea represents a missing link between ancient elephants and their modern counterparts. The finding suggests that mastodons and elephants originated in Africa, contradicting previous theories that placed their origins in Europe and Asia.

SourceUniversity of Michigan·JournalProceedings of the National Academy of Sciences·DateNov 1, 2006

Rehydrate -- your RNA needs it

The study reveals that water molecules trapped inside RNA enzymes form hydrogen bonds with other water molecules or parts of the molecule, creating a domino effect that modifies the structure elsewhere. This network-like behavior is essential for the enzyme's activity.

SourceUniversity of Michigan·JournalProceedings of the National Academy of Sciences·DateAug 22, 2006

Pre-life molecules present in comets

Researchers from the University of Michigan and Harvard-Smithsonian Center for Astrophysics discovered atomic nitrogen in interstellar gas clouds, suggesting pre-life molecules may be present in comets. This finding sheds new light on the early conditions that led to life on Earth.

SourceUniversity of Michigan·JournalNature·DateJul 25, 2006

Bubbles go high-tech to fight tumors

University of Michigan researchers use gas bubbles to block blood flow to tumors, offering a promising new technique in embolotherapy. The method allows for precise control over bubble formation, minimizing damage to surrounding tissue.

SourceUniversity of Michigan·JournalJournal of Biomechanical Engineering·DateJul 20, 2006

Parallel evolution: Proteins do it, too

Evolutionary biologist Jianzhi Zhang discovers parallel evolution of pancreatic enzyme RNASE1 in Asian and African colobine monkeys, showing identical amino acid changes despite separate duplication events. The study reveals a division of labor between old and new genes after duplication.

SourceUniversity of Michigan·JournalNature Genetics·DateJun 12, 2006

Expanding waistlines triggered by your genes

Researchers at U-M's Life Sciences Institute discovered that the MT1-MMP gene regulates fat cell size and metabolic gene expression. In three-dimensional environments, the gene plays a critical role in adipocyte development, potentially leading to novel therapeutics for obesity prevention.

SourceUniversity of Michigan·JournalCell·DateMay 4, 2006

Warming trend may contribute to malaria's rise

A new study by an international team finds that climate change may contribute to malaria's rise, with rising temperatures creating favorable conditions for mosquitoes and pathogen development. The researchers also suggest that other factors such as drug resistance and human migration play roles in the disease's resurgence.

SourceUniversity of Michigan·JournalProceedings of the National Academy of Sciences·DateMar 21, 2006

Less is more, gene study shows

Researchers found that humans lost genes related to the sense of smell, bitter taste, and immune response, which may have improved our ability to fight infections. The loss of the CASPASE12 gene, in particular, led to a stronger immune response, but also made it harder for humans to fight off severe bacterial infections.

SourceUniversity of Michigan·JournalPLOS Biology·DateFeb 13, 2006

Crystal sponges excel at sopping up CO2

Researchers have invented a new class of materials called metal-organic frameworks (MOFs) that can store vast amounts of carbon dioxide. One MOF, dubbed MOF-177, sops up 140% of its weight in CO2 at room temperature and reasonable pressure.

SourceUniversity of Michigan·JournalJournal of the American Chemical Society·DateDec 1, 2005

Building a better hydrogen trap

Scientists create a new class of materials called covalent organic frameworks (COFs), which can store hydrogen more efficiently. By slowing down the synthesis process, researchers can predict the internal structure and properties of COFs, allowing for tailored applications.

SourceUniversity of Michigan·JournalScience·DateNov 17, 2005

Older brains 'rise to the challenge'

Researchers found that older adults increase activation in control-related brain regions and additional frontal brain areas when faced with difficult tasks. In contrast, young adults tend to deactivate certain brain regions. These findings suggest that older adults can adapt to challenging situations, although their brains may respond ...

Research: In environmental policy, we get what we pay for

A new study by University of Michigan researchers finds that market-based incentives, such as pollution taxes and emissions permits, can reduce pollution abatement costs for businesses. However, these approaches may not be effective in areas with localized pollution where the source of pollution matters.

SourceUniversity of Michigan·JournalEnvironment and Natural Resources Journal·DateNov 9, 2005