Researchers discovered that mice, rats, and humans all exhibit the sunk cost fallacy, preferring to continue with a choice despite clear evidence of a better alternative. The study used economic games to test species' willingness to wait for rewards, finding that all three groups became more reluctant to quit as time passed.
Researchers found that the P2RX7 protein influences the body's long-term immune system and helps generate memory cells protecting against certain viruses and reinfection. Certain drugs used to control neuropathic chronic pain can cause these immune memory cells to decay, leaving individuals vulnerable to infections.
Researchers at the University of Minnesota Medical School have developed an algorithm to better identify seriously ill hospitalized patients, empowering them to make informed decisions about their medical care. The data-driven approach aims to reduce unnecessary invasive procedures and improve end-of-life planning.
Scientists successfully regenerate skeletal muscle cells in mice with muscular dystrophy by using cells from animal teratomas. The study showed improved potential with 80% regeneration compared to the current 5-10%.
A recent University of Minnesota Medical School study found a direct link between psychosocial stress and shortened lifespan in mice, identifying cellular senescence mechanisms and diseases associated with aging. The research also observed an increased risk of cardiovascular disease, including early-stage atherosclerosis.
A new study finds that diseases common in the developing world may cause lymphoid tissue fibrosis and impaired vaccine responses. Researchers found significant differences in lymphoid anatomy between Ugandans and US participants, with Ugandans showing evidence of inflammation and immune activation.
A University of Minnesota Medical School study found that existing childcare programs in MN increased healthy food access and reduced screen time, improving children's well-being. The 'Healthy Start, Healthy State' initiatives, such as Farm to Childcare and Let's Move! Child Care, were instrumental in driving these improvements.
Researchers investigated whether an abnormal left atrium or atrial fibrillation itself is the primary driver of poor health outcomes in patients with A-Fib. The study suggests targeting upstream factors to prevent left atrial abnormalities could be a key to preventing stroke and cognitive decline.
Researchers at the University of Minnesota Medical School discovered an unrecognized cyclic pathway structure within the folate biosynthesis pathway, allowing each drug to enhance the activity of the other. This new mechanism has the potential to open doors for identification of other synergistic drug combinations.
The University of Minnesota Medical School's Center for Magnetic Resonance Research has received a NIH R01 grant to investigate the underlying trajectory of brain chemistry in healthy aging and Alzheimer's disease. The project aims to identify abnormal metabolic pathways in Alzheimer's disease.
The University of Minnesota Medical School has received a $892,462 grant from the Helmsley Charitable Trust's Rural Healthcare Program to develop a plan for equipping ambulances with mobile emergency departments. The goal is to improve emergency care for critical-need patients in the greater Minneapolis-St. Paul metropolitan area.
The University of Minnesota Medical School's Center for Magnetic Resonance Research has been awarded a $3.5 million NIH grant to develop new, efficient, and safe stimulation paradigms for Deep Brain Stimulation (DBS). The project aims to improve treatment quality for patients with disabling neurological symptoms by increasing the preci...