Articles tagged with Alcoholism
Researchers found that women experiencing depressive symptoms, binge drinking, or smoking during pregnancy may be at risk for depression and alcohol use during the first postpartum year. Early identification and treatment of these comorbid conditions can benefit both mothers and children.
Researchers found that infant rats willingly ingest large amounts of highly concentrated alcohol during their first exposure, resulting in extremely high blood alcohol levels. This contrasts with adult rats and humans, who typically reject or require initiation procedures to consume alcohol.
A study found that genetic differences are the primary cause of variation in long-term average alcohol intake. Some genes affect both intake and dependence, while others influence only dependence. The research suggests that individuals can make lifestyle choices to improve their health and reduce risk, even with a family history of hea...
The NESARC study reveals high rates of comorbidity between substance use disorders and independent mood and anxiety disorders. Approximately 20% of persons with a current substance use disorder experience a mood or anxiety disorder within the same time period.
A study found that Type A alcoholics who took sertraline showed improved treatment response and maintained gains after treatment ended, while Type B alcoholics did not. In contrast, Type B alcoholics experienced increased heavy drinking after receiving sertraline.
Researchers investigated acamprosate's interactions with alcohol in a six-week study. The findings suggest that acamprosate does not alter the rate of absorption or elimination of alcohol by the body, disrupting effects on performance tasks, or most mood effects. This suggests potential as a medication for treating alcoholism.
A University of Washington study found that adolescent binge drinking is linked to obesity, high blood pressure, and other health issues by age 24. The study identified four distinct patterns of binge drinking among teenagers, which can have serious effects on their health.
Research suggests moderate drinking may lower heart disease risk in older adults but increase breast cancer risk, particularly among women with family history or hormone replacement therapy. Moderate consumption also appears to reduce the risk of diabetes and metabolic syndrome.
A study found that men with high trait anger and low anger control are more likely to exhibit aggressive behavior when intoxicated. Researchers examined 164 healthy male social drinkers and found that those with high trait anger levels were associated with increased aggression, but only among those who reported low anger control.
A recent study found that college students referred for alcohol interventions, often due to disciplinary actions or medical concerns, exhibit higher rates of binge drinking and problematic use. Brief motivational intervention (BMI) and alcohol education (AE) sessions were effective in reducing alcohol use among these students.
Researchers at the University of Illinois Chicago discovered a gene, CREB, that regulates brain function during development and learning. Mice with only one copy of the CREB gene exhibited increased anxiety-like behaviors and consumed more alcohol than normal littermates.
A study found that moderate alcohol consumption increases plasma DHEAS levels in both men and women, decreases testosterone in men, and has no effect on estradiol levels. These findings suggest that DHEAS may play a protective role against atherosclerosis.
A study found that nearly 8 out of 10 establishments sold alcohol to visibly intoxicated patrons, with younger servers more likely to serve. The study suggests increasing enforcement, comprehensive training, and permitting dram-shop liability lawsuits could reduce such incidents.
Researchers used gene therapy to increase dopamine D2 receptor levels, reducing preference for alcohol and consumption by half in genetically predisposed rats. The treatment showed significant reductions in drinking preference and consumption in both groups, with the greatest effects observed within days of treatment.
Researchers identified a strong association between gene GABRA2 and the risk of alcoholism. The study found that tiny differences in this gene are associated with both alcoholism and brainwave patterns linked to alcoholics.
Research reveals that college women are more likely to experience sexual and nonsexual victimization on days they drink, particularly when consuming heavily. The study found that the odds of experiencing aggression were nine times higher on heavy drinking days compared to non-drinking days.
A study found that community-based heavy drinkers have clear brain metabolite changes associated with lower brain function and are likely of behavioral significance. Brain damage is detectable even in those who function relatively well in the community.
A study found that even light to moderate drinking during pregnancy may cause learning and memory difficulties in adolescents. Researchers assessed 580 children and their mothers, and discovered an association between low levels of alcohol consumption and subtle difficulties with verbal/auditory abilities at 14 years old.
Research reveals a strong relationship between drugs of abuse, stress, and the amygdala, suggesting CRF receptor blockers may be a new therapeutic for alcoholics. The study highlights the complex neurobiology of addiction, with compounds blocking CRF receptors potentially providing relief from relapse.
Recent studies suggest that selective serotonin reuptake inhibitors (SSRIs) may be effective in treating social anxiety in alcohol-dependent individuals, particularly those with severe depression. Additionally, anticonvulsants like sodium valproate and atypical antipsychotics like clozapine show promise in reducing alcohol use among bi...
Researchers have found that genetic variations can affect an individual's response to alcohol, with some genes contributing to increased sensitivity and others to tolerance. The study suggests that understanding these biological markers can help develop new treatments for alcohol dependence.
A study found that genetic variation can influence motivation to drink alcohol, particularly to alleviate social anxiety and improve mood. This can lead to enhanced behaviors that increase the risk for alcoholism. The study suggests a link between genetic factors and drinking motives, providing insight into the biology of alcoholism.
The study found an association between a specific GABA receptor gene and alcohol dependence, suggesting a potential genetic link. The findings support the idea that brain overactivation may contribute to predisposition to alcoholism.
Researchers have identified a consistent association between alcohol dependence and the GABRG3 gene, which may suggest a genetic predisposition to increased risk of developing alcoholism. The study found that this gene plays a role in influencing the risk for alcoholism by altering brain state and circuit activity.
Researchers discovered that rats bred to prefer alcohol were healthier and lived longer than those bred to avoid it, regardless of drinking habits. The study found that genetic factors, rather than alcohol consumption itself, contributed to the longevity difference.
A study found that behavioral anger contributes the most to alcohol-related aggression among men and women. Researchers examined healthy social drinkers and found that those with higher behavioral and cognitive anger scores were more likely to exhibit aggressive behavior when intoxicated. The findings suggest that understanding the rel...
A study found that individuals with high levels of social anxiety use alcohol more often to relieve social discomfort and avoid social situations without alcohol. They experience greater relief from anxiety in social situations, but not full relief, suggesting a self-medication strategy that may lead to increased risk of alcoholism.
Researchers found that a compound blocking NPY activity delays alcohol self-administration and reduces rewarding effects of alcohol in mice. This study suggests L-152,804 has potential as a treatment for alcoholism.
A study found that individuals with co-existing alcoholism and antisocial personality disorder exhibit reduced responsiveness to aversive stimuli, including unpleasant photographs. This hyporesponsivity may facilitate maladaptive behavior and increase vulnerability to problems like criminality and substance abuse.
The study found that children of MZ and DZ twins with a history of alcohol dependence were significantly more likely to exhibit alcohol abuse or alcohol dependence than those with non-alcoholic fathers. A low-risk environment can moderate the impact of high genetic risk regarding offspring for the development of alcohol-use disorders.
A new study published in Alcoholism: Clinical & Experimental Research found that alcohol dependence is a concern in American Indian communities, but rates are lower than previously reported. The research highlights cultural differences in alcohol use and dependence among Northern Plains and Southwest tribes.
A study suggests that college students overestimate the amount of fluid needed for a standard drink, leading to significantly higher actual consumption. This could underestimate actual drinking levels on college campuses, exacerbating alcohol misuse issues.
Researchers found that individuals with a family history of alcoholism are more likely to prefer sweet tastes than those without. This preference precedes the development of alcoholism and may serve as a marker for genetic risk. The study suggests that a simple test to assess sweet preference could help identify individuals at risk ear...
Researchers found that adolescent binge drinking leads to tolerance in various biological functions, including altered liver function and brain function. This tolerance can last into adulthood, highlighting the importance of studying its effects during adolescence.
A study found that repeated alcohol detoxifications are associated with increased impairment of cognitive function, specifically frontal-lobe damage. Patients with two or more previous withdrawals performed worse than those with fewer or no experiences in tasks requiring attention and executive function.
Researchers identified a distinct phenotype of individuals with co-existing ADHD and alcoholism, characterized by increased severity of alcohol dependence and earlier age of onset. Adults with ADHD were found to be at high risk of developing an alcohol-use disorder, with a significantly higher daily intake of alcohol.
Research confirms that female alcoholics experience more severe cardiovascular effects from heavy drinking than male counterparts, with these effects emerging sooner and at lower consumption levels. This phenomenon, known as 'telescoping,' highlights the need for women to be aware of their increased risk of heart disease due to alcohol...
A study found that chronic drinking elevates cortisol levels both during intoxication and withdrawal, impacting overall health. Elevated cortisol is also associated with increased risk of medical and psychiatric problems such as diabetes and cognitive deficits.
A recent study found an association between the DdeI polymorphism of the DRD1 gene and sensation seeking among alcoholic males. The research suggests that genetic factors, such as this specific dopamine receptor gene, may play a role in understanding the complex disorder of alcoholism.
A study examines ethnic differences among adolescents who engage in drinking after driving (DD) and riding with drinking drivers (RWDD), finding a distinct need to direct prevention efforts toward Latino youth. RWDD is identified as even more dangerous than DD for adolescents.
A study found that individuals with lower educational attainment experienced poorer drinking outcomes following alcohol treatment, including a shorter time to relapse. The researchers suggest that future studies address issues related to matching patients to optimal treatments.
Researchers found that recovering alcoholics experience persistent sleep disruptions for many months after quitting drinking, with problems with sleep onset being worse than sleep maintenance. Many former alcoholics reported pre-existing sleep problems that predated their alcohol dependence.
A new study found that sexually active young women perceive themselves at low risk for contracting STDs, despite having similar risk profiles as women in higher-risk groups. The researchers highlight the need for healthcare clinicians to address these misconceptions and promote safer sex practices.
A study has identified three chromosomal regions that appear to hold genes affecting low response to alcohol. This research may lead to a better understanding of how genes contribute to alcohol dependence and help develop new treatments.
A study found that doctors and mental-health professionals often fail to address alcohol consumption during visits, even when patients have multiple health or social problems. This missed opportunity can lead to inadequate treatment referrals and counseling.
A study published in Alcoholism: Clinical & Experimental Research found that middle-aged and older alcoholics are at greater risk for suicide than young alcoholic adults. The researchers also discovered an association between increased age, mood disorders, and medically serious suicide attempts.
A study of 778 Ohio State University students found that nearly two-thirds (64%) were in the precontemplation stage, which is associated with increased heavy drinking. In contrast, students who had cut back on their intake reported perceiving more risks and fewer benefits associated with alcohol use.
The study found significant disparities in self-reported versus diagnosed alcoholism rates among elderly individuals, with certain groups, such as those in poor health or aged 75+, being more likely to be under-diagnosed. The researchers identified key risk factors that can inform targeted screenings and interventions.
Research found that alcohol consumption increases hepatitis C virus replication by upregulating nuclear factor kappa B, a key cellular regulator of immune pathways. Alcohol also inhibits the anti-HCV effect of interferon-alpha therapy. Treatment with naltrexone abolishes alcohol actions.
Researchers at Yale University found that adolescents are more vulnerable to addictions due to brain development changes. Brain circuits involved in motivation and addiction undergo rapid changes during adolescence, leading to impulsive behaviors and increased risk of substance abuse.
A study found that individuals with a positive paternal history of alcoholism prefer less salty and sour solutions, indicating unique taste characteristics that may contribute to protection against alcoholism. Researchers suggest that altered taste sensitivity may also play a role in the development of alcoholism risk.
A study published in Alcoholism: Clinical & Experimental Research found that nicotine replacement therapy works as well for smokers with long-term sobriety as it does for smokers without a history of alcoholism. In fact, most smokers with past alcoholism (85%) can quit smoking without difficulty and benefit from nicotine-patch treatment.
Researchers found that topiramate significantly reduced heavy drinking days and increased abstinence days in heavy drinkers compared to placebo. The study also showed substantial reduction in plasma concentrations of the enzyme g-glutamyl transferase, an objective measure of high alcohol consumption.
Researchers found that executive cognitive functioning is more impaired during the descending limb of the blood alcohol concentration curve, when people no longer feel stimulated by alcohol. This effect lasts much longer than previously believed, with significant ramifications for behaviors like driving and aggression.
A new study found that chronic alcohol abuse can cause severe and persistent alterations in hormone levels regulating electrolyte and water balance. After 280 days of strict abstinence, researchers found suppressed AVP levels and elevated ANP levels, indicating long-lasting damage to the body's homeostatic systems.
Rensselaer's active campus/community coalition is addressing alcohol abuse through various programs, including First Year Experience orientation and on-demand educational programs. The university has also distributed billboards, flyers, and free license verifiers to reduce underage drinking.
Elderly alcoholics with marital and partner relationship difficulties are at increased risk of suicide. Researchers also found that medically serious suicide attempters with alcoholism often have mood disorders and financial difficulties.
Alcohol abusers may show signs of improvement that are part of their natural cycle, not indicative of true recovery. Most treatments may not last long enough to make a real positive impact, as the disease is dynamic and changes over time.
A recent study found that alcohol use can exacerbate injury severity in motor vehicle crashes, increasing the risk of bleeding, heart problems, and organ damage. The study's findings suggest that clinicians should take an active role in preventing alcohol use where there is risk of injury.
Chronic alcoholism damages the cerebellum and frontal lobes, leading to motor deficits that persist even after long-term abstinence. Functional magnetic resonance imaging (fMRI) reveals that alcoholics' brains compensate for damage by recruiting new brain regions to perform simple tasks.