Articles tagged with Alcoholism
A new study found that alcoholics show deficits in visuoperception and frontal executive functioning even with prolonged sobriety. Researchers assessed visuoperception and perceptual learning tasks in detoxified alcoholic men compared to control men, revealing differences in cognitive processes and memory strategies.
Binge drinking was associated with a 73% higher death rate after heart attacks compared to non-binging patients. The study also found that survivors who binged during the year prior to their heart attack were 1.91 times more likely to die of any cause in the next several years.
The study found that individuals with a family history of alcoholism were less sensitive to ketamine and exhibited altered NMDA receptor function. This suggests a genetic predisposition to vulnerability to heavy drinking in the presence of environmental and social factors.
A study in flies reveals that rapid and chronic tolerance operate via different neurobiological mechanisms and genes. Rapid tolerance is blocked by a drug inhibiting protein synthesis, while a fly mutant lacking octopamine shows reduced rapid tolerance.
Researchers found that more alcohol is consumed in beer form than previously believed, with a national mean alcohol content of beer ranging from 4.58% to 4.75%. This translates to approximately 10 additional standard drinks yearly for each person aged 14 or older in the US.
Research suggests that binge drinking has a detrimental effect on platelet adhesion and aggregation, leading to increased risk of cardiovascular mortality. In contrast, moderate red wine consumption may have beneficial effects on cardiovascular disease due to its high polyphenol count.
A recent study examined the genetic factors underlying a low response to alcohol and found potential links to several gene categories. The research suggests that these genes could play a significant role in the development of alcoholism, particularly in individuals who experience little or no effect from drinking.
According to a recent study, youth drinking rates have stabilized in the US since the early 1990s, with over 80% of adolescents consuming alcohol by age 12th-grader. The stable prevalence rates are concerning, highlighting the need for continued efforts to prevent underage drinking.
Research suggests a combination of sweet liking and novelty seeking can predict alcoholism in individuals, particularly children of alcoholic fathers. Sweet likers with high novelty seeking are more likely to develop alcoholism due to related brain function and sensitivity to rewarding effects.
Research finds that rates of drinking among American youth have remained relatively stable since the 1990s, with high prevalence rates among 8th-12th graders. The study highlights the need for new approaches to reduce alcohol use and its associated risks.
Researchers found that infant rats willingly ingest large amounts of highly concentrated alcohol during their first exposure, resulting in extremely high blood alcohol levels. This contrasts with adult rats and humans, who typically reject or require initiation procedures to consume alcohol.
A study found that genetic differences are the primary cause of variation in long-term average alcohol intake. Some genes affect both intake and dependence, while others influence only dependence. The research suggests that individuals can make lifestyle choices to improve their health and reduce risk, even with a family history of hea...
Researchers found that women experiencing depressive symptoms, binge drinking, or smoking during pregnancy may be at risk for depression and alcohol use during the first postpartum year. Early identification and treatment of these comorbid conditions can benefit both mothers and children.
The NESARC study reveals high rates of comorbidity between substance use disorders and independent mood and anxiety disorders. Approximately 20% of persons with a current substance use disorder experience a mood or anxiety disorder within the same time period.
Researchers investigated acamprosate's interactions with alcohol in a six-week study. The findings suggest that acamprosate does not alter the rate of absorption or elimination of alcohol by the body, disrupting effects on performance tasks, or most mood effects. This suggests potential as a medication for treating alcoholism.
A study found that Type A alcoholics who took sertraline showed improved treatment response and maintained gains after treatment ended, while Type B alcoholics did not. In contrast, Type B alcoholics experienced increased heavy drinking after receiving sertraline.
A University of Washington study found that adolescent binge drinking is linked to obesity, high blood pressure, and other health issues by age 24. The study identified four distinct patterns of binge drinking among teenagers, which can have serious effects on their health.
A recent study found that college students referred for alcohol interventions, often due to disciplinary actions or medical concerns, exhibit higher rates of binge drinking and problematic use. Brief motivational intervention (BMI) and alcohol education (AE) sessions were effective in reducing alcohol use among these students.
Research suggests moderate drinking may lower heart disease risk in older adults but increase breast cancer risk, particularly among women with family history or hormone replacement therapy. Moderate consumption also appears to reduce the risk of diabetes and metabolic syndrome.
A study found that men with high trait anger and low anger control are more likely to exhibit aggressive behavior when intoxicated. Researchers examined 164 healthy male social drinkers and found that those with high trait anger levels were associated with increased aggression, but only among those who reported low anger control.
Researchers at the University of Illinois Chicago discovered a gene, CREB, that regulates brain function during development and learning. Mice with only one copy of the CREB gene exhibited increased anxiety-like behaviors and consumed more alcohol than normal littermates.
A study found that moderate alcohol consumption increases plasma DHEAS levels in both men and women, decreases testosterone in men, and has no effect on estradiol levels. These findings suggest that DHEAS may play a protective role against atherosclerosis.
A study found that nearly 8 out of 10 establishments sold alcohol to visibly intoxicated patrons, with younger servers more likely to serve. The study suggests increasing enforcement, comprehensive training, and permitting dram-shop liability lawsuits could reduce such incidents.
Researchers used gene therapy to increase dopamine D2 receptor levels, reducing preference for alcohol and consumption by half in genetically predisposed rats. The treatment showed significant reductions in drinking preference and consumption in both groups, with the greatest effects observed within days of treatment.
Researchers identified a strong association between gene GABRA2 and the risk of alcoholism. The study found that tiny differences in this gene are associated with both alcoholism and brainwave patterns linked to alcoholics.
A study found that community-based heavy drinkers have clear brain metabolite changes associated with lower brain function and are likely of behavioral significance. Brain damage is detectable even in those who function relatively well in the community.
Research reveals that college women are more likely to experience sexual and nonsexual victimization on days they drink, particularly when consuming heavily. The study found that the odds of experiencing aggression were nine times higher on heavy drinking days compared to non-drinking days.
A study found that even light to moderate drinking during pregnancy may cause learning and memory difficulties in adolescents. Researchers assessed 580 children and their mothers, and discovered an association between low levels of alcohol consumption and subtle difficulties with verbal/auditory abilities at 14 years old.
Research reveals a strong relationship between drugs of abuse, stress, and the amygdala, suggesting CRF receptor blockers may be a new therapeutic for alcoholics. The study highlights the complex neurobiology of addiction, with compounds blocking CRF receptors potentially providing relief from relapse.
Researchers have found that genetic variations can affect an individual's response to alcohol, with some genes contributing to increased sensitivity and others to tolerance. The study suggests that understanding these biological markers can help develop new treatments for alcohol dependence.
Recent studies suggest that selective serotonin reuptake inhibitors (SSRIs) may be effective in treating social anxiety in alcohol-dependent individuals, particularly those with severe depression. Additionally, anticonvulsants like sodium valproate and atypical antipsychotics like clozapine show promise in reducing alcohol use among bi...
Researchers discovered that rats bred to prefer alcohol were healthier and lived longer than those bred to avoid it, regardless of drinking habits. The study found that genetic factors, rather than alcohol consumption itself, contributed to the longevity difference.
A study found that genetic variation can influence motivation to drink alcohol, particularly to alleviate social anxiety and improve mood. This can lead to enhanced behaviors that increase the risk for alcoholism. The study suggests a link between genetic factors and drinking motives, providing insight into the biology of alcoholism.
The study found an association between a specific GABA receptor gene and alcohol dependence, suggesting a potential genetic link. The findings support the idea that brain overactivation may contribute to predisposition to alcoholism.
Researchers have identified a consistent association between alcohol dependence and the GABRG3 gene, which may suggest a genetic predisposition to increased risk of developing alcoholism. The study found that this gene plays a role in influencing the risk for alcoholism by altering brain state and circuit activity.
A study found that individuals with high levels of social anxiety use alcohol more often to relieve social discomfort and avoid social situations without alcohol. They experience greater relief from anxiety in social situations, but not full relief, suggesting a self-medication strategy that may lead to increased risk of alcoholism.
Researchers found that a compound blocking NPY activity delays alcohol self-administration and reduces rewarding effects of alcohol in mice. This study suggests L-152,804 has potential as a treatment for alcoholism.
A study found that individuals with co-existing alcoholism and antisocial personality disorder exhibit reduced responsiveness to aversive stimuli, including unpleasant photographs. This hyporesponsivity may facilitate maladaptive behavior and increase vulnerability to problems like criminality and substance abuse.
A study found that behavioral anger contributes the most to alcohol-related aggression among men and women. Researchers examined healthy social drinkers and found that those with higher behavioral and cognitive anger scores were more likely to exhibit aggressive behavior when intoxicated. The findings suggest that understanding the rel...
The study found that children of MZ and DZ twins with a history of alcohol dependence were significantly more likely to exhibit alcohol abuse or alcohol dependence than those with non-alcoholic fathers. A low-risk environment can moderate the impact of high genetic risk regarding offspring for the development of alcohol-use disorders.
A study suggests that college students overestimate the amount of fluid needed for a standard drink, leading to significantly higher actual consumption. This could underestimate actual drinking levels on college campuses, exacerbating alcohol misuse issues.
Researchers found that individuals with a family history of alcoholism are more likely to prefer sweet tastes than those without. This preference precedes the development of alcoholism and may serve as a marker for genetic risk. The study suggests that a simple test to assess sweet preference could help identify individuals at risk ear...
A new study published in Alcoholism: Clinical & Experimental Research found that alcohol dependence is a concern in American Indian communities, but rates are lower than previously reported. The research highlights cultural differences in alcohol use and dependence among Northern Plains and Southwest tribes.
A study found that repeated alcohol detoxifications are associated with increased impairment of cognitive function, specifically frontal-lobe damage. Patients with two or more previous withdrawals performed worse than those with fewer or no experiences in tasks requiring attention and executive function.
Researchers identified a distinct phenotype of individuals with co-existing ADHD and alcoholism, characterized by increased severity of alcohol dependence and earlier age of onset. Adults with ADHD were found to be at high risk of developing an alcohol-use disorder, with a significantly higher daily intake of alcohol.
Researchers found that adolescent binge drinking leads to tolerance in various biological functions, including altered liver function and brain function. This tolerance can last into adulthood, highlighting the importance of studying its effects during adolescence.
A study found that chronic drinking elevates cortisol levels both during intoxication and withdrawal, impacting overall health. Elevated cortisol is also associated with increased risk of medical and psychiatric problems such as diabetes and cognitive deficits.
Research confirms that female alcoholics experience more severe cardiovascular effects from heavy drinking than male counterparts, with these effects emerging sooner and at lower consumption levels. This phenomenon, known as 'telescoping,' highlights the need for women to be aware of their increased risk of heart disease due to alcohol...
Researchers found that recovering alcoholics experience persistent sleep disruptions for many months after quitting drinking, with problems with sleep onset being worse than sleep maintenance. Many former alcoholics reported pre-existing sleep problems that predated their alcohol dependence.
A recent study found an association between the DdeI polymorphism of the DRD1 gene and sensation seeking among alcoholic males. The research suggests that genetic factors, such as this specific dopamine receptor gene, may play a role in understanding the complex disorder of alcoholism.
A study examines ethnic differences among adolescents who engage in drinking after driving (DD) and riding with drinking drivers (RWDD), finding a distinct need to direct prevention efforts toward Latino youth. RWDD is identified as even more dangerous than DD for adolescents.
A study found that individuals with lower educational attainment experienced poorer drinking outcomes following alcohol treatment, including a shorter time to relapse. The researchers suggest that future studies address issues related to matching patients to optimal treatments.
A new study found that sexually active young women perceive themselves at low risk for contracting STDs, despite having similar risk profiles as women in higher-risk groups. The researchers highlight the need for healthcare clinicians to address these misconceptions and promote safer sex practices.
A study published in Alcoholism: Clinical & Experimental Research found that middle-aged and older alcoholics are at greater risk for suicide than young alcoholic adults. The researchers also discovered an association between increased age, mood disorders, and medically serious suicide attempts.
A study has identified three chromosomal regions that appear to hold genes affecting low response to alcohol. This research may lead to a better understanding of how genes contribute to alcohol dependence and help develop new treatments.
A study found that doctors and mental-health professionals often fail to address alcohol consumption during visits, even when patients have multiple health or social problems. This missed opportunity can lead to inadequate treatment referrals and counseling.
A study of 778 Ohio State University students found that nearly two-thirds (64%) were in the precontemplation stage, which is associated with increased heavy drinking. In contrast, students who had cut back on their intake reported perceiving more risks and fewer benefits associated with alcohol use.
The study found significant disparities in self-reported versus diagnosed alcoholism rates among elderly individuals, with certain groups, such as those in poor health or aged 75+, being more likely to be under-diagnosed. The researchers identified key risk factors that can inform targeted screenings and interventions.
Research found that alcohol consumption increases hepatitis C virus replication by upregulating nuclear factor kappa B, a key cellular regulator of immune pathways. Alcohol also inhibits the anti-HCV effect of interferon-alpha therapy. Treatment with naltrexone abolishes alcohol actions.
Researchers at Yale University found that adolescents are more vulnerable to addictions due to brain development changes. Brain circuits involved in motivation and addiction undergo rapid changes during adolescence, leading to impulsive behaviors and increased risk of substance abuse.