Articles tagged with Hyperglycemia
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Researchers found that hyperglycemia promotes the production of inflammatory cells, which contribute to plaque build-up in blood vessels. Treating diabetic mice with a drug that lowers blood sugar levels reduced circulating monocyte and neutrophil numbers and allowed plaques to heal.
Researchers analyzed 82 million drug-related search queries from 6 million users and found that those who searched for both drugs were more likely to look up symptoms associated with high blood sugar. This suggests that online searches could be used as an early warning system for potential drug safety issues.
Two studies published in the Journal of Bone and Joint Surgery found that high blood sugar and obesity significantly increase the risk of surgical site infections after orthopaedic trauma and total joint replacement. Nearly one-third of hospital admissions without diabetes have hyperglycemia, which is associated with longer stays, ICU ...
Researchers found a significant association between chronically elevated glucose levels and minute levels of troponin T, a blood marker for heart damage. The high-sensitivity test detected low levels of cTnT in 66% of the study population, suggesting potential pathways for diabetes-related heart disease.
The Endocrine Society releases a clinical practice guideline recommending that all hospitalized patients, regardless of diabetes status, have their blood glucose levels tested. This can help prevent complications and mortality associated with hyperglycemia in non-critically ill patients.
Eating mixed nuts daily boosts serotonin levels in MetS patients, decreasing hunger and improving heart health. A 12-week nut-enriched diet showed significant biochemical effects, including reduced inflammation and cardiovascular risk factors.
Joslin Diabetes Center researchers discovered that plasma kallikrein interferes with brain clotting, leading to increased bleeding during strokes. Normalizing blood glucose levels may block this effect and reduce brain hemorrhage.
High blood glucose levels after surgery may be a significant risk factor for surgical site infections in general surgery patients, according to a recent study. The authors found that postoperative hyperglycemia was the most important risk factor for surgical site infections in both general and colorectal cancer surgery patients.
Researchers found a significant association between acute illness complicated with hyperglycaemia and the development of type II diabetes or glucose intolerance. Patients with hospital-acquired hyperglycaemia during critical illness are at increased risk of developing diabetes, suggesting regular monitoring is necessary.
Researchers at the University of Warwick have identified central obesity, high blood pressure, and high blood sugar as the most dangerous combination of health factors for developing metabolic syndrome. This combination can increase the risk of heart attack by doubling it and mortality rates by three times.
A study of 13,817 individuals with diabetes aged 66 and older found that starting antipsychotic treatment increased the risk of hospitalization for hyperglycemia. The risk was highest among those just beginning treatment, highlighting the need for enhanced glucose monitoring.
A genome-wide association study found that a mutation near the MTNR1B gene is associated with increased average blood sugar levels and a higher risk of type 2 diabetes. The researchers suggest that treating sleep problems could partly tackle diabetes and high blood sugar levels.
Dr. Michael Brownlee, a renowned expert in diabetes research, has been awarded the prestigious David Rumbough Award by JDRF for his outstanding contributions to understanding diabetic complications. His innovative work on hyperglycemia-induced damage and the discovery of novel molecular pathways have significantly advanced the field.
A University of California, Irvine study found children with type-1 diabetes exhale higher concentrations of methyl nitrates when hyperglycemic. The researchers developed a breath device that can warn diabetics of high blood sugar levels and the need for insulin.
Researchers found that patients with uncontrolled high blood sugar before surgery are 6.2 times more likely to develop pulmonary embolism, a life-threatening condition. Tightening glucose control can reduce this risk and hospital stays.
Dr. Brownlee, a leading researcher in type 1 diabetes, has been awarded the prestigious JDRF Scholar Award to pursue innovative research directions. He aims to develop strategies to reduce susceptibility to diabetic complications through his studies on hyperglycemic memory and free radical production.
A new approach to managing type 2 diabetes has been demonstrated in a Canadian study, showing that early addition of insulin glargine therapy can safely achieve better glycemic and metabolic outcomes. The results show lower and steady blood glucose levels more quickly and often compared to oral medications.
A new approach to glucose management in intensive care units is suggested by the findings, which indicate that tight control can improve vascular function and lower infection risk. The study analyzed data from over 1,800 patients and found a significant association between high blood sugar levels and increased death rates.
Researchers have discovered a potential therapeutic target for treating hyperglycemic damage in endothelial cells, which is linked to both diabetes and cardiovascular disease. Inhibiting GAPDH activity by poly(ADP-ribose) polymerase could activate three major pathways of damage, providing new avenues for treatment.
A new study by Johns Hopkins Medicine has found a link between hyperglycemia and retinopathy of prematurity (ROP) in premature infants. Infants with ROP had higher daily blood sugar levels compared to healthy peers, with increased risk almost doubling for each 10 mg/dl increase in average monthly glucose.
A study by Emory researchers found that controlling blood glucose levels through aggressive insulin therapy can significantly reduce mortality in critically-ill neurological patients. The research, conducted in a neurointensive care unit, used continuous intravenous insulin drip to achieve tighter control of glucose levels.
Scientists have developed a new mouse model of lipoatrophic diabetes, which reveals the genetic pathway underlying the disease. The study also suggests that leptin therapy may be effective in treating humans with lipoatrophic diabetes.
Researchers found that stroke patients with high blood sugar levels had a higher risk of death within 30 days, 1 year, and 5 years after the stroke. The study also revealed that uncontrolled blood sugar levels during hospitalization contributed to longer hospital stays and increased medical costs.
Researchers studied 171 hospital patients with diabetes mellitus and found that sliding scale insulin regimens provided no benefit. Patients on standing regimens fared better than those on sliding scale regimens, which tripled the risk of hyperglycemia when used alone.