A new study finds that critically injured patients who arrived at trauma centers via private transportation had similar mortality rates, hospital stays, and complications as those transported by emergency medical services (EMS). However, they tended to arrive at the center more quickly following injury, which was associated with better...
Two case reports found that rosiglitazone, a new oral anti-diabetic drug, appeared to be associated with liver damage. In contrast, a large retrospective study on hepatitis C virus showed that infected individuals developed few liver-related illnesses, suggesting they may be at lower risk for progressive liver disease.
A study found that tumor necrosis factor-alpha (TNF-alpha) plays a crucial role in early liver damage caused by alcohol consumption. The researchers used gene knockout technology to show that TNF-alpha mediates the development of liver injury, leading to potential new drug therapies for conditions affecting millions of Americans.
Scientists have identified TNF-alpha as a major contributor to early liver injury from long-term alcohol consumption, paving the way for new treatments. The study used gene knockout technology and found that mice lacking TNF receptors fared better on measures of liver injury after alcohol exposure.
Researchers found an immune molecule that kills damaged cells indirectly by closing receptors to a life-saving protein, shedding new insight on neurodegenerative diseases such as Alzheimer's and stroke. The findings could lead to targeted treatments for brain injuries and diseases involving neurodegeneration.
Researchers found that liver ischemia/reperfusion injury induces a caspase-dependent apoptosis in endothelial cells. The study identified the type of affected cell and the molecular pathway responsible for the damage, opening doors to develop therapies to prevent or reduce liver preservation injury.
Toxicologists have made a groundbreaking discovery that chemical compounds formed during the reaction of free radicals with human tissue can be detected in the urine within just a few days. This breakthrough has the potential to provide an earlier indication of the damaging effects of chemotherapy on cancer patients.
Researchers at White River Junction Veterans Administration Medical Center and Dartmouth Medical School have found that more than one protein plays a major role in making acetaminophen toxic to the liver of rats administered alcohol. The study identified CYP3A as another culprit that may cause even more liver damage in individuals who ...