Articles tagged with Internal Medicine
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Two studies found that patients with kidney disease are at increased risk of death after a heart attack, receiving less-aggressive treatment. Meanwhile, researchers report four cases of muscle damage caused by statins, highlighting the need for closer monitoring.
A researcher has reviewed over 350 clinical studies to find evidence-based therapies for stroke prevention, highlighting the underutilization of anti-coagulation therapy in high-risk patients. The study aims to make this evidence accessible to clinicians to improve healthcare outcomes.
A Canadian National Breast Cancer Screening Study found that annual mammography for five years had no impact on breast cancer deaths in women aged 40-49. The US Preventive Services Task Force recommends starting mammography at age 40, but evidence is considered 'fair' due to conflicting results.
A retrospective analysis of 4,054 study participants found that enalapril, an ACE inhibitor commonly given to patients with heart failure, is effective in both black and white populations. Despite equal response rates, black patients still had increased rates of progression to heart failure.
The American College of Physicians recommends screening adults over 50 for colorectal cancer. The Task Force identified two screening methods that have been shown to reduce death from colorectal cancer: the fecal occult blood test and flexible sigmoidoscopy.
The ACP-ASIM published 'Osteoporosis' guide provides the latest scientific evidence on osteoporosis and essential information on its origins and progress. It addresses every facet of osteoporosis, a common disease that can be identified through non-invasive tests and treated with new effective drugs to reduce fractures.
Celebrating its 75th anniversary, Annals of Internal Medicine has published influential articles on Lyme disease, HIV/AIDS, and evidence-based medicine. The journal has continued to evolve with innovative features like structured abstracts and international discussions on editorial issues.
The US Preventive Services Task Force (USPSTF) advises women at low risk for breast cancer to avoid taking drugs like tamoxifen or raloxifene. Women at high risk, however, should have open discussions with their doctors about the benefits and risks of these medications.
A study of 373 intravenous drug users found significant reductions in emergency department use among those using needle-exchange programs, including Hispanics, men, and those with mental illness. The study suggests that needle-exchange-based health care services can reduce emergency department use among high-risk IDUs.
A study found contaminated E. coli bacteria in hot sauces from popular tourist restaurants in Mexico and Texas, increasing the risk of travelers' diarrhea. A simple test can detect peripheral arterial disease by comparing blood pressure in the arm and lower leg.
A new series of articles explores the causes of medical errors, highlighting the limitations of relying solely on patient charts. Increasing the number of reviewers and requiring confidence in negligence can reduce rates of negligent events.
Researchers found that cocaine elevates body temperature by impairing the body's ability to increase skin-blood flow, sweat, and perceive excessive heat stress. Cocaine abuse in hot temperatures increases the risk of serious heat-related injuries, including heat stroke and death.
A study by Michigan Medicine researchers found that 11% of doctors are willing to misrepresent patient information to obtain HMO approval for surgery or additional procedures. The 'hassle factor' plays a significant role in this behavior, with more physicians willing to deceive if the appeal process is longer or more burdensome.
The USPSTF recommends screening all adults for depression, as five percent to nine percent of adult patients in primary care settings suffer from the condition. Depression can be treated with counseling, medications, or both, reducing health care utilization and costs associated with lost workdays.
Two new studies published in Annals of Internal Medicine shed light on diabetes diagnosis and management. A mathematical model predicts type 2 diabetes with high accuracy, while a report card reveals significant gaps in diabetes care. Additionally, experts emphasize the importance of preventive methods to address partner violence.
A study of 118 people with early Lyme disease found most had a red rash with central redness, not the traditional bull's-eye description. The patients' liver function returned to normal after treatment with antibiotics. Meanwhile, a case report describes pioglitazone causing liver damage in a diabetic patient.
A study of 115 residents found that 76% suffered from burnout, with half being depressed and nine percent misusing alcohol. Residents with heavy education-related debts were more likely to moonlight and experience depression.
A Mayo Clinic study reveals a shift in heart disease burden from men to women and older adults. Heart attack rates decreased among younger men but increased among women over 80, while survival rates remained unchanged for those over 75.
Acupuncture has been shown to be effective in treating vomiting after chemotherapy or surgery, as well as nausea associated with pregnancy. However, its effectiveness in treating chronic pain, back pain, and headache is still a topic of debate, with conflicting results from clinical trials.
A large study of men's health habits found that a prudent diet significantly reduces the risk of developing type 2 diabetes. The study indicates that avoiding weight gain and eating a balanced diet may substantially reduce this risk, highlighting the importance of a healthy lifestyle in preventing the disease.
Three influential organizations of internal medicine physicians unveil a new charter on medical professionalism, outlining three fundamental principles and ten definitive professional responsibilities. The charter aims to promote an action agenda for the profession, addressing challenges in healthcare delivery, technology, and globaliz...
A study in Annals of Internal Medicine finds that accurate profiling of physician care depends on study design, and that most quality initiatives fail to adjust for patient characteristics. Additionally, researchers estimate that colonoscopy is a cost-effective strategy for investigating rectal bleeding in young people
The USPSTF recommends discussing aspirin therapy with adult patients at increased risk of coronary heart disease, such as those with unfavorable cholesterol levels, smoking, or hypertension. Aspirin may help prevent heart attacks in these individuals, but its benefits and harms should be carefully weighed.
A study found that comprehensive care and access to staff members are key factors in successful patient-physician relationships for lower-income women. These features can lead to higher trust, compassion, and communication ratings among patients.
A recent study of over 2,000 patients found that good communication is crucial for building trust with physicians. Patients who experience poor communication or feel left out of medical decisions are more likely to consider changing their primary care provider.
Six popular herbal therapies - Ginkgo, St John's wort, Ginseng, Echinacea, Saw palmetto, and Kava - have varying levels of effectiveness and safety. Prednisone, a glucocorticoid, reduced swelling and progression of damage to joints in patients with early active rheumatoid arthritis.
The article highlights three articles addressing hypertension control: managing diabetes, blood pressure-lowering drugs, and the DASH diet. Additionally, a study reveals gaps in newspaper articles on mammography, which often oversimplify or misrepresent scientific evidence.
Two studies examine the link between sex hormones and coronary artery spasm, finding that estrogen levels during menstruation affect blood vessel function. Automated external defibrillators are also shown to be safe and easy to use by trained laypersons, paving the way for potential home sales.
UT Southwestern Medical Center has been awarded $3.6 million in funding to support 19 research projects across various disciplines. The largest grant will go towards developing a cancer-detecting blood test, which has already shown promising results in clinical trials.
A new study found that 41% of physicians would perform at least one action proscribed by the AMA's ethics guidelines, while 25% would perform five or more actions. The study suggests that some physicians are morally confused about their role in capital punishment.
Two reports on HBV infection shed light on the effectiveness of vaccination programs in reducing the disease rate and carrier state. A study found that 70% of carriers recovered within ten years after treatment, while a nationwide vaccination program for adults is crucial to prevent further transmission.
The ACP-ASIM survey found that 60% of respondents under 40 use handheld computers to access drug information and clinical references. The organization is expanding its educational resources through a Personal Digital Assistant Portal on its website.
Researchers will study 12 astronaut crew members before, during and after space missions to assess cardiac mass, compliance and relaxation. Findings may help prevent cardiac atrophy and arrhythmias in individuals confined to long-term bed rest or with conditions associated with cardiac stiffness.
A study of internists found that physicians often do not follow best practices due to concerns about patient individuality. The study suggests that noncompliance with guidelines can be a valid reflection of questions about their usefulness and applicability.
A study of 2,437 HIV-infected adults found that patients with case managers had fewer unmet needs and higher use of HIV medications. Screening for hereditary colorectal cancer has been shown to work and may be cost-effective, particularly for relatives of affected individuals.
Local experts urge a $300 million increase in Ryan White/CARE Act funding to ensure stable medical care and treatment for newly diagnosed patients. HIV infection can be managed as a chronic disease with access to services and new anti-AIDS drugs.
Researchers found that women taking hormone replacement therapy were 40% more likely to require gallbladder surgery than those on placebo. Additionally, high-dose cyclophosphamide was successful in treating some aplastic anemia patients, offering potential implications for the treatment of severe autoimmune diseases.
The American College of Physicians announces new standards for manuscript submission, emphasizing author disclosure of sponsor involvement. These revised guidelines, developed by the International Committee of Medical Journal Editors, aim to prevent pharmaceutical companies from controlling study data and results.
A study published in Annals of Internal Medicine found that African-American patients receive fewer heart procedures than white patients, despite having a higher risk of heart disease. Researchers suggest various factors, including patient education and physician attitudes, may contribute to these disparities.
The American College of Physicians-American Society of Internal Medicine has released a comprehensive guide for primary care doctors on obesity diagnosis and management. Obesity rates increased by 30% between 1980 and 1994, carrying significant direct health care costs for the United States. The guide addresses key aspects of medical a...
A study found raw (uncooked), contaminated alfalfa and clover sprouts cause illnesses in California, leading to six outbreaks of salmonellosis and E. coli 0157. Researchers also discovered that hormone replacement therapy (HRT) may help lower blood pressure in women as they age.
The journal launches a series on complementary and alternative medicine (CAM), classifying over 200 therapies into eight categories. ACP-ASIM opposes the legalization of physician-assisted suicide, citing concerns about inadequate care at end-of-life.
The American College of Physicians-American Society of Internal Medicine opposes physician-assisted suicide, considering it a threat to the patient-physician relationship. Instead, they suggest improving access to hospice care, palliative care, and pain management.
The Annals series examines complementary and alternative medicine (CAM), classifying hundreds of therapies into a new taxonomy. CAM modalities like herbs, acupuncture, and homeopathy are studied, as well as the social context and effectiveness of these practices.
A recent study by Dr. Tamera Coyne-Beasley found that 59% of surveyed law enforcement officers stored firearms unlocked, while 68% kept their guns loaded. The researchers called for mandatory safety training and stricter firearm storage laws to address the issue.
Postmenopausal women taking hormone replacement therapy for less than one year had a 25% increase in risk for recurrent heart disease, while those taking hormones for two years or longer had decreased risk. UTI patients successfully diagnosed and managed their own care with short-term antibiotics.
A new study found that women younger than 60 had a higher mortality rate after heart attacks than men of the same age, with an almost threefold higher risk for death. Researchers also discovered that inhaled insulin shows promise for treating type 2 diabetes, improving blood sugar control without serious side effects.
A study by researchers compared colonoscopy to fecal occult blood tests (FOBT) and sigmoidoscopy in screening for colorectal cancer. The findings show that colonoscopy is the most cost-effective option, reducing death rates at relatively low costs by removing precancerous polyps and detecting cancer at early stages.
A recent study suggests that hospitals and healthcare organizations can make quick and efficient changes to lower back pain treatment by adopting new guidelines and strategies. The ideal approach involves extensive use of patient education and self-care, with a focus on exercise therapy over diagnostic imaging tests.
The new book, edited by Howard Libman and Harvey J. Makadon, offers high-quality primary medical care to HIV-infected patients. With contributions from 23 AIDS experts, the book covers pathogenesis, antiretroviral therapy, and infection control.
A study found that prescribing sterile needles is ethical and clinically appropriate for injection drug users. Smoking daily can lead to impaired fasting glucose and type 2 diabetes. Long-term use of drugs promoting gastroesophageal reflux also increases the risk of esophageal adenocarcinoma.
A prospective study of adults with type 2 diabetes found non-traditional risk factors for heart disease, including albumin and fibrinogen levels. Women internists in Pennsylvania earned 14% less per hour than male counterparts. Low body weight was linked to increased fracture risk in women.
A study published in Archives of Internal Medicine found that a combination of exercise and weight loss significantly reduces high blood pressure in overweight individuals. The researchers, led by James A. Blumenthal, Ph.D., randomly assigned 133 sedentary men and women to either aerobic exercise alone or a behavioral weight management...
A new study using a decision analysis model found that sildenafil was as cost-effective as kidney dialysis, cholesterol lowering medication or coronary artery bypass surgery. An editorial questions whether health insurance should cover treatment for erectile dysfunction when many Americans are not covered.
A self-help program using patented software increases smokers' success rates when combined with nicotine replacement therapy, shows a 56% increase in quitting at 12 weeks compared to standard materials. The Committed Quitters program provides tailored behavioral materials to support individuals in their quit attempt.
A new study found that asthma patients who experience more depressive symptoms have a lower quality of life. The study also showed that household income is negatively correlated with the level of depressive symptoms among patients.
A prospective cohort study found that regular exercise can benefit men with type 2 diabetes, while low physical fitness is associated with mortality. Meanwhile, a dangerous combination of blood thinners and intravenous steroids requires daily monitoring to prevent life-threatening bleeding.
A consensus panel convened by the University of Pennsylvania's Center for Bioethics discusses guidelines, treatments, and legal responses to assisted suicide. The panel aims to establish safeguards that make physician-assisted suicide voluntary, regulated, and an option of last resort.
A survey of family physicians found that those with a prior history of depression or somatic complaints were less likely to consider the possibility of serious illnesses and order testing. Cognitive shortcuts can be helpful but also lead to false generalizations, highlighting the need for awareness among physicians.
This issue of Annals of Internal Medicine offers guidance on identifying and treating depression in terminally ill patients. A new program combining physical therapy and exercise is shown to effectively manage osteoarthritis symptoms, potentially delaying surgery for affected adults. Meanwhile, a pet parrot infection has been transmitt...