Articles tagged with Enzyme Kinetics
A specific region of Dicer must be activated to achieve proper cell division and reproduction, a discovery that sheds light on the regulation of this enzyme's critical role in both cancer biology and fertility. This finding opens new avenues for studying how small epigenetic changes contribute to disease.
Researchers found that alcohol causes DNA damage, which can lead to cancer, and discovered a repair mechanism using the SXE enzyme complex. Individuals with genetic mutations affecting DNA repair may be more susceptible to alcohol-related cancers.
A new AI-powered tool, EZSpecificity, can predict the best enzyme-substrate combination for various applications. The tool outperformed existing models in accuracy, especially for halogenase enzymes.
Pharmaceutical scientists at NUS developed DOMEK method to characterise enzyme-substrate interactions, enabling analysis of thousands of potential substrates. The technique combines mRNA display and next-generation sequencing to calculate specificity constant for each substrate.
Researchers at UC Berkeley developed a method to understand the isotope signatures of methane from different environments using CRISPR. This study can change how scientists calculate the contributions of various environmental sources to Earth's total methane budget.
Scientists from the University of Bath have identified two new families of chemical compounds that inhibit alpha-methylacyl-CoA racemase (MCR) in Mycobacterium tuberculosis, a key enzyme for TB survival. This breakthrough could lead to new treatments for TB and potentially other diseases like prostate cancer.
Researchers at Kobe University have created a new test feed for the fungal molecular machine, allowing them to observe its close-to-natural action. This breakthrough enables the characterization of the enzyme's reaction speed and affinity, crucial parameters for industrial application.
Researchers at McGill University discovered that phosphatases of regenerating liver (PRLs) are overexpressed in some cancers, making cells more metastatic and driving disease progression. The study sheds light on PRLs' role in binding magnesium transporters, a common pathway among all studied species.
Researchers from the University of Illinois at Urbana-Champaign created a remote laboratory activity to teach undergraduate students about enzyme kinetics. The at-home kit included basic equipment and protocols that allowed students to conduct experiments and collect data, providing an alternative to traditional lab techniques.