Articles tagged with Cell Proliferation
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A team of researchers led by Gary Gilliland discovered that certain leukemia oncogenes can reactivate self-renewal programs in mature white blood cells. This finding has significant implications for understanding and treating chronic myeloid leukemia, a disease fueled by a small population of cancer stem cells.
Research found soy infant formula's high concentration of genistein may hinder intestinal cell proliferation, a critical organ system development phase. However, clinical data suggests soy formulas are safe but may have unseen effects.
Researchers at Temple University validated the c-myb gene as a potential cancer drug target by demonstrating its critical role in white blood cell formation. The study found that deleting the gene reduced cell proliferation and the risk of developing cancer, offering hope for future breast cancer treatments.
Researchers at PTC Therapeutics have discovered a new biochemical pathway that controls cell growth modulation. This finding has significant implications for the development of therapeutics targeting cancer cells, which rely on deregulated translation to grow uncontrollably.
Researchers have identified a critical gene called Lgl1, which plays a vital role in shaping cell behavior during embryonic brain development. The study found that mice lacking this gene exhibit dramatic abnormalities and resemble human patients with medulloblastoma, a type of brain tumor.
Researchers found that FGF-2 supplementation limits existing neuron loss while promoting new neuron generation in the hippocampal dentate gyrus following traumatic brain injury. This approach may offer a rational strategy for treating brain injury by enhancing neurogenesis and reducing neurodegeneration.
Scientists have discovered a tumor-suppressor gene in fruit flies called hippo that controls cell production and death. The researchers found that removing the hippo gene led to tumor formation in every organ of the fruit fly, highlighting its crucial role in regulating cell growth.
Duke University researchers have successfully grown human arteries in a laboratory using 'immortalized' cells, overcoming the hurdle of human artery cells not being able to divide long enough. The team used the hTERT gene to extend the life span of smooth muscle cells, allowing them to form functional arteries.
Researchers at WashU Medicine have successfully grown cells known as Tr1 cells in the laboratory, which can suppress immune responses. This breakthrough could lead to new treatments for autoimmune diseases such as lupus and rheumatoid arthritis, as well as provide insights into infectious diseases like measles and meningitis.
Researchers at Cold Spring Harbor Laboratory found that altering nitric oxide levels in developing tadpoles significantly affects brain size and cell number. Nitric oxide signals cells to stop proliferating, enabling specialization into distinct types.
Involuting mammary glands undergo two stages of apoptosis, with the first wave triggered by Fas binding to its ligand FasL. Mutant animals lacking Fas or FasL experience delayed epithelial cell death.
Researchers found that NF-kappaB links growth factor signaling with proto-oncogenes Myc, Akt, and Ras. The molecular mechanism regulates cell growth and death, providing a built-in protection against cancer.
Researchers at Cedars-Sinai Medical Center are launching a clinical trial to assess the impact of isoflavones, found in clover and soybeans, on the human endometrium. The study aims to determine whether these plant compounds can counteract estrogen's proliferative effects and reduce the risk of endometrial cancer.
Researchers at Virginia Tech have discovered a protein called Replication Protein A (RPA) that plays a crucial role in regulating cell differentiation and proliferation. The study's findings suggest that RPA could be a potential target for therapeutic intervention in cancer treatment, offering new hope for gene therapy.