NF-kappaB plays a complex role in atherosclerosis, both promoting and inhibiting inflammation. In mice deficient in LDL receptors and NF-kappaB activation, lesions were larger and more advanced, containing more necrosis and macrophages.
A new treatment approach combines a tailored medication regimen with the RAINBOW psychotherapy program to alleviate symptoms of bipolar disorder in children. The program has shown promising results, with 94% of children improving after treatment.
Researchers at UCSF have identified nearly all proteins in yeast, shedding light on their activity, location, and quantity. The study provides the most comprehensive picture yet of protein activity in higher organisms, offering new tools for understanding gene regulation and disease relationships.
Researchers found that FGF-2 supplementation limits existing neuron loss while promoting new neuron generation in the hippocampal dentate gyrus following traumatic brain injury. This approach may offer a rational strategy for treating brain injury by enhancing neurogenesis and reducing neurodegeneration.
Researchers have discovered a new protein, TUG, that controls the movement of GLUT4, a glucose transporter in cells. This finding may lead to new drug targets for treating Type 2 diabetes.
Researchers at Rutgers-Newark are developing new nanoparticle structures that combine organic and inorganic materials. The team's innovative approach may lead to more efficient solar-energy conversion cells and devices capable of detecting pollutants.
Researchers have created a comprehensive atlas of yeast proteins, allowing for the measurement of abundance and localization with high sensitivity. This breakthrough enables insights into protein function and cellular behavior, surpassing previous methods that only detected abundant proteins.
Dawn Wooley, a WSU researcher, is working with a team of universities to develop diagnostic tools, therapeutics, and vaccines for deadly agents and viruses. The Midwest Center of Excellence aims to create solutions to counter biological threats, with a focus on airborne agents.
A study published in the American Journal of Managed Care found that guideline-based cancer pain management offers effective pain relief in 80% of patients compared to 30% effectiveness for non-specialty providers. The targeted approach ensures a pre-determined treatment plan, reducing variability and increasing patient outcomes.
A Dartmouth study has found that RNA molecules can catalyze the transformation of normal prion proteins into disease-causing counterparts, potentially leading to early detection and treatment of prion diseases. The discovery opens new avenues for exploration in diagnosis and treatment of neurodegenerative disorders.
Researchers at Temple University have identified a genetic mutation responsible for inflammation in Crohn's disease. The study found that a specific protein, kininogen, plays a key role in the development of the disease.
The National Institute of Environmental Health Sciences (NIEHS) has awarded $9 million to support ongoing research on the health consequences of the 9/11 attacks. The funding will continue to study human exposures, respiratory and psychological problems, and provide education and training for workers and communities.
Researchers analyzed 1.2 million screening result records, finding that extending Pap tests to 3-year intervals carries a small risk of 3-5 cancers per 100,000 people, similar to annual breast cancer incidence in men ages 45-64.
Researchers validated Einstein's theory by applying information theory to laser experiments, showing that information cannot exceed the speed of light. The study found that fast light pulses did not travel faster than light speed, but rather were delayed slightly compared to vacuum speeds.
Researchers found that elevated ozone levels can reduce soil carbon formation, which is essential for forest health and climate regulation. The study's findings suggest that high ozone levels may hinder forests' ability to absorb excess carbon dioxide, threatening global efforts to mitigate greenhouse gas emissions.
Researchers found that fibroblast growth factor-2 (FGF-2) boosts new brain cell production and protects existing neurons from degeneration following traumatic brain injury. The study suggests FGF-2 supplementation may improve TBI outcomes.
A new study by Oklahoma researchers has identified autoantibodies years before the clinical features of lupus and found specific autoantibodies close to disease onset. The study, published in the New England Journal of Medicine, holds important clinical value and may lead to new therapies for the disease.
Hutton's animal and plant breeding experiments demonstrated seminal variation, passed on to offspring. Darwin applied this principle independently, assembling evidence that convinced the scientific world.
Researchers propose an international treaty to control air pollutants like ozone and aerosols, which can cause respiratory diseases. The treaty aims to unite countries in addressing short-term health risks while also reducing carbon dioxide emissions.
The DETER project aims to create a closed, isolated network that can represent the entire Internet for testing and improving cybersecurity tools. The facility will enable researchers to test existing and new security technology using various attack techniques.
Linda Brzustowicz will lead research on hereditary patterns of autistic behaviors, analyzing 'trio' samples from autistic individuals and their parents to define genes linked to the disorder. The study aims to better understand, treat, and potentially prevent autism.
Rutgers-Newark has received a powerful computer grant, which will enable researchers to analyze brain activity more efficiently. The new supercomputing cluster allows for faster processing of massive amounts of data generated by human brain scans.
The University of Georgia has been awarded a $3.9 million NSF grant to study the genetic analysis of meristem organization and leaf initiation in plants. The team aims to improve laser dissection microscopy techniques for plant tissues, allowing researchers to analyze thousands of genes simultaneously.
Despite 80% of processed American food containing genetically modified ingredients, only 26% of Americans believe they have ever eaten GM foods. A new study found that self-reported and objective knowledge of biotechnology remains low in the US, but opinions on GM foods are open to change.