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New ways to modulate cell activity remotely

Researchers at the University of Pennsylvania have developed a protein called Melt that can be toggled by temperature, allowing for precise control over cellular pathways. The breakthrough enables non-invasive therapy options for cancer treatment and basic research, potentially leading to more targeted and less toxic treatments.

SourceUniversity of Pennsylvania·JournalNature Methods·TypeExperimental study·DateJan 29, 2025

SibFU scientists simulated the intracellular environment of a luminescent bacteria cell

The study investigated the effect of viscosity on enzymatic reactions in a simulated intracellular environment. Scientists found that sucrose limited enzyme mobility more efficiently than glycerol, affecting reaction rates and mechanisms. The approach to constructing metabolic chains inside luminescent bacteria cells was proposed.

SourceSiberian Federal University·JournalMolecular Catalysis·DateOct 26, 2018