Articles tagged with Myeloid Cells
Researchers discovered a novel molecular pathway used by myeloid cells to regulate blood vessel patterning in the developing retina. The pathway, involving the Wnt protein signaling network, has potential as a therapeutic option for fighting retinal diseases and cancers.
Researchers mapped epigenetic changes during blood cell differentiation, revealing complex patterns and potential applications for stem cell therapies. The study's findings could guide understanding of diseases like leukemia and lymphoma, paving the way for new treatments.
Researchers found that tumor-secreted exosomes increase myeloid-derived suppressor cells, inhibiting immune activation and accelerating tumor metastasis. The study identified the role of MyD88 in this process, suggesting potential strategies to develop immune-stimulating tumor vaccines.
STDs like genital herpes and chlamydia increase the risk of becoming infected with HIV due to inflammation in Langerhans cells. Anti-inflammatory therapies might help prevent HIV transmission by modulating the immune response.
Researchers at the University of Pennsylvania School of Medicine have found that juvenile cells on their way to becoming mature immune cells can develop into either T cells or other blood-cell types. This challenges the currently accepted model of T-cell development, which suggests that these cells are committed to the T-cell path from...
Researchers found that the N-Myc gene triggers cancer when paired with growth-promoting protein IL-3 and causes cell suicide without it. The study also shows that immortalized cells overexpressing N-Myc become more aggressive and produce fewer growth-inhibiting proteins.
Researchers found that modified bone marrow cells reduced MS symptoms, nerve damage, and increased tissue debris clearance when injected into mice with EAE at disease peak. The study opens up further research avenues for human multiple sclerosis treatment.