Articles tagged with Gene Regulation
Researchers propose that the APP tail participates in gene expression by binding to DNA, potentially activating transcription. This finding may shed light on mechanisms behind Alzheimer's disease and raise concerns about the effectiveness of drugs intended to prevent plaque formation.
Researchers have identified the three-dimensional atomic structure of a critical gene-regulating molecule, revealing its importance in human diseases such as cancers, autoimmune disorders, and developmental disorders. The discovery could lead to the development of new treatments and therapies for these conditions.
Researchers at TSRI have cloned the TOC1 gene, which regulates circadian rhythms in plants, providing insight into how plants adapt to daily environmental changes. The study's findings suggest that understanding plant internal clocks may also elucidate clock mechanisms in other species, including humans.
Scientists have identified a number of genes specifically regulated by the hormone leptin, which is produced by fat tissue and secreted into the bloodstream. These findings offer new insights into how leptin causes fat loss and decreased appetite, and may also provide new targets for drugs designed to stimulate weight loss.
Researchers identify a genetic marker associated with panic disorder, linked to variations in cholecystokinin (CCK) receptor function. The study found that this variation could be a risk factor for panic attacks and may be useful in diagnosis and therapeutic approaches.
Researchers found a mutant gene in C. elegans that doubles adult lifespan when mutated, suggesting its role in regulating aging. The gene encodes a PI(3)K enzyme, which may trigger a biochemical program leading to decreased aging and senescence.