A new study reveals that astrocytes actively participate in motor-learning circuit rewiring by eliminating synapses in the striatum. The research identifies MEGF10 as a key molecular mediator of this process, which is regulated by dopamine signaling and neural activity.
Researchers have identified a specific group of neurons in the brain responsible for suppressing binge drinking behavior. The discovery may lead to new therapeutic targets for treating alcohol dependency and related health challenges.
Scientists at Okinawa Institute of Science and Technology identify a positive glutamate-NO-glutamate feedback loop that blocks long-term potentiation and impairs learning and memory. The study suggests that this loop may explain memory loss in stroke patients and potentially offer a solution for treatment.
Researchers from Xi'an Jiaotong-Liverpool University found that brain stimulation combined with a nose spray containing nanoparticles can improve recovery after ischemic stroke. The treatment increased cognitive and motor functions, and weighed more quickly than those treated with TMS alone.
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Researchers at King Abdullah University of Science & Technology have developed a method to produce crocins, a key ingredient in saffron, using a common garden plant. This breakthrough could lead to sustainable and efficient production of these compounds for pharmaceuticals, food coloring, and flavor additives.
A study from Edith Cowan University reveals that electrical stimulation on specific nerves and relaxation techniques can reduce neural amplification in the spinal cord, which may help alleviate involuntary muscle spasms. These methods could provide a non-pharmacological alternative to current treatment options.
A new study suggests that supplementing a diet with Ascidiacea, also known as sea squirts, reverses some main signs of aging in animal models. The researchers found that plasmalogens, vital to body processes, decrease with age and contribute to neurodegenerative diseases like Alzheimer's and Parkinson's.
A new study shows that a specific protein, tomosyn, plays a crucial role in determining the communication style of neurons. The study found that tomosyn enables tonic neurons to release glutamate in measured doses, allowing them to exhibit plasticity and adapt to changes in their circuit partners.
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Researchers at IST Austria identified a new learning rule that strengthens connections between neurons in the CA3 region of the hippocampus, even when neurons fire in reverse order. This discovery may explain robust learning and storage of spatial information in the brain.
Scientists are exploring the potential of adult stem cells from bone marrow to treat brain damage by manipulating neural markers. The research, published in Developmental Biology, aims to develop a way to introduce stem cells into the brain and modify them to repair damaged brain cells.
A study found that male birds' brains are activated in 'reward' areas when they sing to attract females, similar to the brain response to addictive drugs. This suggests that social interactions, like courtship, can activate the same brain reward circuits as natural and artificial rewards.
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New research from the University of Wisconsin-Madison found that synapses, nerve cell connections central to brain plasticity, are strong when awake and weak when asleep. This challenges the widely-held idea that sleep is essential for consolidating information through synaptic strengthening.