Articles tagged with Cerebrum
The Hippenmeyer group has developed a stable mouse stem cell line and created a robust and reproducible mouse cortical organoid protocol. By comparing developmental stages of the mouse brain with those of the organoids using single-cell sequencing, they found similar cell populations and molecular programs.
A new study published in Science Advances reveals that neuronal precursor cells divide into two independent lineages, producing distinct types of projection neurons. This challenges previous assumptions about the development of neural stem cells and sheds light on how the cerebral cortex arises.
Researchers develop tailored revascularization approach for moyamoya disease, improving circulation while minimizing complications. The technique, called STAPC, uses vessel diameter, blood-flow dynamics, and recipient brain arteries to guide surgical decisions.
Researchers at University of California - Riverside discovered that the primary cilium, a microscopic structure inside nearly every cell, plays a critical role in brain development. The study found that proteins associated with the cilium are directly linked to human developmental disorders and that protein production occurs directly w...
A new study reveals that astrocytes actively participate in motor-learning circuit rewiring by eliminating synapses in the striatum. The research identifies MEGF10 as a key molecular mediator of this process, which is regulated by dopamine signaling and neural activity.
Intra-arterial tenecteplase significantly reduces the risk of symptomatic intracranial hemorrhage and mortality in patients with acute large vessel occlusion. The treatment also improves neurological outcomes at 90 days without increasing complications.
A comprehensive analysis reveals how brains generalize learning from previous experiences to new scenarios, mapping neural pathways from hippocampus to cortex. The study's findings highlight the critical role of the hippocampus and prefrontal cortex in cognitive generalization.
Scientists discover blocking gasdermin D, a key inflammatory protein, improves liver health while damaging kidneys and brain in severe liver disease patients. The study's findings suggest that future therapies may need to target this pathway in a more nuanced way.
Earlier anticoagulation reversal is associated with improved outcomes after intracerebral hemorrhage, supporting efforts to accelerate evaluation and treatment. This study supports intensive care strategies to improve survival rates among patients with this devastating form of stroke.
A study of 205 adolescent football players and 70 noncontact control athletes reveals discernible structural and physiological differences in brain regions associated with mental health. These findings suggest a potential link between football playing and mental health outcomes.
Researchers identified the dorsal precentral gyrus as a critical region in controlling speech, enabling individuals to adapt to feedback errors. This finding may lead to targeted treatments for conditions like stuttering and Parkinson's disease.
Researchers at Nagoya University have developed a new analytical system for real-time monitoring of metabolites in the brain, overcoming previous limitations in sensitivity and invasiveness. The system, combining probe electrospray ionization (PESI) and tandem mass spectrometry (MS/MS), successfully monitored cerebrum metabolites with ...
A study by Catherine Limperopoulos, PhD, found that the cerebellum grows rapidly late in gestation and is tightly interconnected with the cerebral hemispheres. Premature babies with cerebellar damage experience significant developmental delays, including motor problems, functional limitations, and global developmental delays.