Researchers have found that the lymphatic system is crucial for removing cholesterol from peripheral tissues, including artery walls. The study suggests that therapies supporting lymphatic transport could enhance cholesterol clearance and potentially treat atherosclerotic vascular disease.
Researchers at the University of Rochester Medical Center have discovered a new brain cleaning system called the glymphatic system, which acts like a shadow plumbing system to drain away waste products from the brain. The system is highly organized and operates on a much larger scale than previously thought.
A rare subset of diseases affecting the lymphatic system, including lymphangiomatosis and Gorham's disease, are focused on in a special issue of Lymphatic Research and Biology. The articles shed light on current knowledge, ongoing research, and key differences from other lymphatic disorders.
Researchers found a gene, Prox1, essential for normal development of the lymphatic system and proper formation of one-way valves controlling fluid movement between systems. The study provides new insights into valve defects affecting children and adults.
Scientists discover a new connection between macrophages and lymph vessels in the eyes, which could lead to new therapies for eye diseases like diabetic retinopathy. The study also suggests that this link may be universal and involved in spreading cancer.
Researchers studying the common Australian gecko Christinus marmoratus have found a protein growth factor that contributes to its ability to quickly regenerate its tail after losing it. This discovery is encouraging for treating human lymphoedema, but more research is needed.
Molecular signals play a critical role in separating the lymphatic system from the circulatory system during fetal development. The study sheds light on the mechanisms behind this separation and its potential therapeutic applications, including influencing blood vessel growth and tumor treatment.