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ESE and ESPE launch joint transition of care guidance to improve outcomes for young people moving from child to adult endocrine care

The ESE and ESPE have launched a landmark Joint Clinical Practice Guidance to support structured and effective transition of young people with endocrine conditions. The Guidance provides practical, evidence-based recommendations to ensure continuity, safety and quality of care during this critical phase in a patient's life.

New EndoCompass Research Roadmap calls for coordinated investment to tackle Europe’s hormone health challenge

The European Society of Endocrinology has released the EndoCompass Research Roadmap, a major new initiative to align research efforts and improve funding strategies for hormone-related health challenges. The roadmap identifies specific research needs across eight endocrine specialties and five cross-cutting areas.

SourceEuropean Society of Endocrinology·TypeCommentary/editorial·DateOct 17, 2025

Cause of sleep disturbance in cardiac disease identified: Ganglia play previously unrecognized role

A study published in Science reveals that ganglia in the neck region are responsible for disrupting melatonin production and causing sleep disturbances in people with heart conditions. Researchers found that macrophages accumulate in the ganglion, leading to inflammation and scarring, which can be treated with drugs.

SourceTechnical University of Munich (TUM)·JournalScience·TypeExperimental study·DateJul 20, 2023

Shining new light on the pineal gland

Researchers discovered a genetic link between left-right brain asymmetry and melatonin production in fish, shedding light on pineal gland function. The study found that a protein called Bsx controls the development of the pineal complex, leading to disrupted sleep-wake cycles.

SourceUniversity of Freiburg·JournalDevelopment·DateJul 4, 2018

The role of dopamine in sleep regulation

Researchers discovered that dopamine inhibits melatonin production by forming 'heteromers' with norepinephrine receptors, regulating the body's circadian rhythm. This discovery could lead to new treatments for circadian rhythm disturbances and sleep disorders affecting 40% of the world's population.

SourcePLOS·JournalPLOS Biology·DateJun 19, 2012