Articles tagged with Thermogenesis
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A single episode of intense exercise reduces subsequent physical activity and body temperature in mice, leading to weight gain. The study highlights the importance of considering not only calories burned during exercise but also subsequent activity levels and circadian rhythm for effective weight loss.
Research from Stockholm University reveals that marsupials possess a not fully evolved form of brown fat, a crucial finding for understanding the origin and regulation of this heat-producing organ. The study suggests that the gene networks required to enable thermogenesis existed before the divergence of marsupials and placental mammals.
Researchers found that Amystrops sap beetles pollinate fragrant screw pines, contrary to previous assumptions about wind-pollination. The study also revealed floral thermogenesis in male and female flowers of Pandanus odorifer.
Researchers found that MAFB inhibits the expression of inflammatory cytokine IL-6, reducing sympathetic nerve fiber density and impairing thermogenic capacity. This regulation plays a key role in maintaining body temperature in cold environments.
The study reveals changes in motor protein structure and energy consumption during hibernation, highlighting key differences between large and small hibernators. Myosin plays a crucial role in non-shivering thermogenesis, with smaller mammals experiencing increased ATP consumption at lower temperatures.
Researchers found that thyroid hormones of the mother during pregnancy affect the later activity of brown adipose tissue in offspring. High maternal thyroid hormone levels were associated with more active brown fat in offspring.
A new study from Karolinska Institutet found that exercising in the early active phase increased gene expression involved in fat breakdown and thermogenesis, leading to a higher metabolic rate. This effect was independent of food intake and may prove beneficial for people who are overweight.
Researchers found that Sirtuin 7 regulates brown adipose tissue functions, leading to suppressed energy expenditure and thermogenesis. The study reveals a molecular pathway involving protein deacylation and mRNA binding, which will have implications for treating hypermetabolic conditions like cancer and obesity.
Researchers aim to develop a drug that enhances brown adipose tissue response to cold exposure, potentially treating hypothermia and arctic exploration challenges. The new screening method could also optimize drug development for diseases and infections, reducing costs and time.
Scientists at CNIC discovered a complex network between liver tissue connections that allows the liver to regulate body temperature. The secretion of IL-12 by liver-infiltrating macrophages blocks FGF21 production, reducing heat generation by brown fat in mice.
Alzheimer's disease causes cells to overheat due to amyloid-beta aggregation, which can lead to more aggregates forming. The researchers found a drug compound could stop this process, potentially leading to new treatments.
Researchers at UNIGE discovered that temperature changes trigger organ-specific effects in all tissues, leading to distinct gene expression profiles. The study's web-based application provides access to thousands of gene expression profiles, enabling further research and potential therapeutic applications.
Researchers identified an estrogen-activated neurocircuit that stimulates thermogenesis and physical activity, increasing energy expenditure and preventing obesity. The circuit responds to changes in ambient temperature and nutritional status, and its conservation in males suggests a potential role in weight regulation.
Researchers discovered that naked mole-rats rapidly decrease uncoupling protein 1 (UCP1) in brown adipose tissue to conserve energy in hypoxia. This mechanism may hold secrets for humans to survive and thrive in low-oxygen environments, particularly in relation to diseases like stroke and chronic pulmonary disorders.
Researchers found that young male winter swimmers had better thermoregulation and higher heat loss due to frequent sauna exposure. They also showed increased brown fat tissue activity, particularly in response to cold exposure.
The University of Maryland associate professor will use genetics, cell biology, and pharmacology to examine the mechanisms of copper transport and its connection to thermogenesis and fat burning. The research aims to improve human health by understanding how copper relates to hypothermia, obesity, and diabetes.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that eating a large breakfast instead of a large dinner creates twice as high diet-induced thermogenesis. This process measures how well metabolism is working, and can differ depending on mealtime.
Researchers at Ohio University are exploring a protein that naturally occurs in the body to prevent obesity and type 2 diabetes. The protein, Apolipoprotein A-IV, is known to act as a satiation protein, telling the body to stop eating.
Researchers at TUM demonstrated that food increases thermogenesis in brown fat, contrary to the long-held assumption that it only responds to cold. This discovery could lead to new ways to prevent obesity and diabetes.
A new study reveals that cold temperatures can transform white fat cells into 'beige' cells, which perform thermogenesis like brown fat cells. This process could potentially reduce the symptoms of metabolic diseases such as diabetes and obesity.
New research reveals cinnamaldehyde's ability to induce thermogenesis in fat cells, improving metabolic health. The compound may offer a non-pharmacological approach to combating obesity and related health issues.
A Kent State biologist has received a $450,000 grant to investigate how the body allocates energy and burns fat. Her research aims to understand how thermogenesis, the biological phenomenon of burning caloric energy, can be used to induce weight loss in humans.
The study reveals that TRPV2 is essential for thermogenesis in mouse brown adipose tissue. Without TRPV2, mice exhibit impaired thermogenesis and increased obesity on high-fat diet treatment.
A study published in Nature Communication found that a protein called sLR11 acts to inhibit thermogenesis, or heat production, in fat cells, making it harder for the body to burn excess fat. This protein is produced by fat cells and increases with total fat mass, suggesting its role in storing energy over long periods.
Researchers at The Scripps Research Institute have identified a signaling pathway that activates the powerful calorie-burning process in brown fat cells. The study found that a protein called GADD45γ works alongside PGC-1α to boost thermogenesis, offering new possibilities for treating obesity and diabetes.
A new drug has been found to increase the amount of energy burned by fat tissue, leading to significant weight loss and improved metabolic health. The drug, GC-1, mimics the activity of thyroid hormone and has been shown to promote thermogenesis in white adipose tissue.
Researchers found that inactivating key genes involved in 'fat-burning' can increase energy expenditure and lower diet-induced obesity. By forcing the body to use less efficient methods, mice became resistant to obesity despite consuming a high-fat diet.
Capsaicin from hot peppers directly induces thermogenesis by altering muscle protein SERCA, leading to increased heat production. This process could be used to design more potent compounds for treating hypothermia.
Diet-induced thermogenesis is an intricate system of communications masterminded by the brain that produces heat and helps prevent obesity. By removing beta adrenergic receptors, researchers found that mice fed a high-fat diet grew massively obese, highlighting the importance of this pathway in preventing weight gain.