Articles tagged with Signaling Pathways
A team of researchers investigated the molecular basis of memory in living mice, identifying a critical molecule involved in learning. The study revealed that long-term potentiation (LTP) and learning share a common molecular basis, with the TrkB receptor playing a central role.
Researchers discovered that signals from rat whiskers travel through distinct regions in the thalamus along separate pathways for movement, touch, and complex signals. These pathways function within parallel feedback loops, enabling the brain to implement new behaviors by building on lower-level sensory inputs.
A UCSD study reveals that anthrax toxins, known as lethal factor and edema factor, can cause cellular damage and death in fruit fly Drosophila melanogaster. The findings suggest that fruit flies can be used to test the effects of anthrax toxins on signaling pathways shared by flies and humans.
Myxococcus xanthus uses all three known phosphate signalling pathways and a partial fourth pathway in combination to detect and utilize phosphates. The bacterium's complex system enables it to find phosphates in different states or conditions, exploiting them for energy.
A trio of plant genes have been found to play a crucial role in regulating the density of microscopic pores called stomata, which are essential for photosynthesis. By understanding how these genes function, scientists can gain insights into how plants evolved to survive on land and how they adapt to changing environmental conditions.
Researchers at OHSU discovered a novel compound called STX that activates a rapid signaling pathway in nerve cells, providing an alternative to estrogen replacement therapy. The new compound shows promise in alleviating menopause symptoms and may be more effective than existing treatments.
Researchers have created a protein mimetic that induces relaxation in smooth muscle cells by adding a phosphate group, making it effective for treating conditions like coronary artery disease. The mimetic is promising for promoting blood vessel relaxation and could lead to more successful coronary bypass surgeries.
Researchers discovered two enzymes necessary for mice to process three basic tastes, challenging the long-held view that distinct machinery is needed. The study also found that restoring one enzyme can selectively restore specific taste modalities.
The study found that exisulind significantly suppressed the rise in PSA levels compared to placebo, especially in high-risk patients. Exisulind therapy also lengthened the median PSA doubling time, suggesting a delay in disease progression.