Articles tagged with Molecules
A blended antioxidant supplement improved spatial learning ability and short-term memory in supplement-treated aged mice. The discovery suggests that the supplements may also prevent age-related cognitive decline in humans and mitigate muscle frailty.
Researchers at the University of São Paulo have tested a synthetic molecule called AD-9308, which has shown potential in treating heart failure by activating the enzyme aldehyde dehydrogenase 2. The study found that the molecule improved mitochondrial filtration, eliminating cellular pollutants and boosting heart function by up to 40%.
The study successfully observed the chiro-optical effect at the nanoscale, demonstrating the ability to analyze the chiral structure of matter using light. Different images were obtained when illuminating with right- or left-circularly polarized light, clarifying that local handedness can be distinguished.
Rice University chemists have discovered that gold nanoparticles are synthesized from gold buckyballs, a finding that could revolutionize nanoparticle synthesis. This discovery was made by Matthew Jones and Liang Qiao, who found that the commonly used golden 'seed' particles were actually cousins of the original buckyballs.
Researchers at the University of Colorado Boulder have developed a new way to recycle polyethylene terephthalate (PET) plastic using electricity and chemical reactions. In small-scale lab experiments, PET was broken down into its basic building blocks, which can be recovered and potentially reused to make new plastic bottles.
Kolomeisky aims to develop analytical models that quantify the role of heterogeneity in chemical and biological processes. He plans to explore its impact on catalytic reactions, antimicrobial peptides and early cancer development.
A team of researchers from China and the UK has developed new ways to optimise the production of solar fuels by creating novel photocatalysts. These photocatalysts, such as titanium dioxide with boron nitride, can absorb more wavelengths of light and produce more hydrogen compared to traditional methods.
A team of Japanese researchers has successfully developed a recycling photoreactor that enables the synthesis of optically pure compounds with high yields, achieving an optical purity of 98-99%. The system uses a two-step rapid photoracemization process and can produce enantiomerically pure chiral sulfoxides in yields higher than 80%.
Three pre-clinical studies published in Journal of Pharmaceutical Analysis explore the molecular mechanisms underlying cardiovascular and neurological diseases, providing new avenues for therapeutic strategies.
Researchers at Durham University and the University of York have developed new concepts about the shape and dynamic nature of carbon-based molecules. They found that a simple rearrangement of a molecular cage structure can lead to inversion of mirror image forms, making carbon-centred chirality dynamic and responsive.
Researchers have observed steric effects, the interactions of molecules depending on their spatial orientation, in a chemical reaction involving non-polar molecules for the first time. This breakthrough opens the door to an entirely new way to control chemical reactions.
Researchers at UCSF's Cell Design Institute engineered cells with customized adhesion molecules to form complex multicellular ensembles in predictable ways. The discovery represents a major step toward building tissues and organs through regenerative medicine.
Researchers at UCSF discovered a small molecule called ISRIB that can reverse the neural and cognitive effects of concussion in mice, weeks after an injury occurred. The drug blocks the integrated stress response, which became chronically activated in damaged neurons, restoring normal spine dynamics and cognitive function.
A research group from Tokyo University of Science has discovered molecular features that govern the filling process at nanoscales, enabling finer resolutions in ultraviolet nanoimprint lithography. The findings provide valuable insights for guiding the selection and design of optimized resists for sub-10 nm resolution.
Researchers from Tokyo University of Science developed novel complex-peptide hybrids that induce programmed cell death in apoptosis-resistant cancer cells through paraptosis. The compounds, syn-6 and anti-6, inhibit cell death by uncoupling mitochondrial calcium uptake and inducing cytoplasmic vacuolization, leading to cell death.
Researchers have identified new biomarkers to detect non-small cell lung cancer in its early stages through a blood test, offering improved survival chances. The approach can also identify potential drug resistance, allowing clinicians to choose alternative treatment options.
Researchers have discovered a new type of triterpenes in fungi that don't require squalene, overturning current knowledge and offering a new approach to pharmaceutical science. This breakthrough opens up possibilities for creating more valuable compounds with anti-inflammatory, anti-cancer, and other properties.
A study published in Current Biology found that people share similar odour preferences regardless of cultural background. The researchers discovered that the structure of the odour molecule determines whether a smell is considered pleasant or not.
UC Riverside scientists developed a technique to map tryptophan production, opening the door to new treatment drugs. By understanding how bacteria make tryptophan, researchers can create enzymes that shut down this process, killing invasive bacterial cells without affecting human cells.
Scientists at the University of Missouri study photodissociation reactions on the quantum level, revealing strong quantum effects that challenge classical 'billiard-ball' models. The research could lead to a better understanding of atmospheric chemistry and develop new theoretical frameworks.
In 2021, researchers made notable discoveries, such as the identification of pain-causing proteins in snake venom and the development of bite-sized protein structures that can be felt with the tongue. The year also saw significant progress in plastics recycling and molecular editing, which holds promise for medicinal chemists.
Scientists devised a method to analyze the NPC directly inside cells, capturing its true size and structure. The results showed that the pore had a wider central channel than previously thought, emphasizing the importance of analyzing complex molecules in their native environments.