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Durham University researchers achieve world-leading quantum entanglement of molecules using magic-wavelength optical tweezers

Researchers at Durham University have successfully demonstrated long-lasting quantum entanglement between molecules, a key capability for next-generation quantum technology. The team achieved exceptionally high entanglement fidelity, reaching levels over 92%, enabling precision measurements in quantum sensing and simulating complex qua...

SourceDurham University·JournalNature·DateJan 15, 2025

Exploring excited state dynamics: Advancements in fluorescence and material design

Recent research at Shinshu University explores how molecular structure and geometry influence light emission in aggregation-induced emission molecules. The study reveals that changes in molecular shape affect emission behavior in both solution and solid states, enabling innovations in material design and energy interactions.

SourceShinshu University·JournalJournal of the American Chemical Society·TypeImaging analysis·DateDec 16, 2024

Toxic chemicals can be detected with new AI method

A new AI method developed by Swedish researchers can identify toxic substances based on their chemical structure, potentially replacing animal testing. The method has been shown to be more accurate and broadly applicable than existing computational tools, offering a promising alternative for environmental research and authorities.

SourceChalmers University of Technology·JournalScience Advances·TypeData/statistical analysis·DateMay 2, 2024

New strategy for assessing the applicability of reactions

Chemists develop new reactions using model systems and substrates to demonstrate versatility. A new computer-aided method reduces subjective bias by analyzing real pharmaceutical compounds' complexity and structural properties. This improves data quality and facilitates machine learning applications.

SourceUniversity of Münster·JournalACS Central Science·TypeComputational simulation/modeling·DateApr 10, 2024

Molecule tested at University of São Paulo, in Brazil, proves able to mitigate heart failure

Researchers at the University of São Paulo have tested a synthetic molecule called AD-9308, which has shown potential in treating heart failure by activating the enzyme aldehyde dehydrogenase 2. The study found that the molecule improved mitochondrial filtration, eliminating cellular pollutants and boosting heart function by up to 40%.

New recipes for better solar fuel production

A team of researchers from China and the UK has developed new ways to optimise the production of solar fuels by creating novel photocatalysts. These photocatalysts, such as titanium dioxide with boron nitride, can absorb more wavelengths of light and produce more hydrogen compared to traditional methods.

SourceXi'an Jiaotong-Liverpool University·JournalApplied Surface Science·TypeExperimental study·DateJun 11, 2023

A novel green photoreactor for the synthesis of desirable chiral enantiomers

A team of Japanese researchers has successfully developed a recycling photoreactor that enables the synthesis of optically pure compounds with high yields, achieving an optical purity of 98-99%. The system uses a two-step rapid photoracemization process and can produce enantiomerically pure chiral sulfoxides in yields higher than 80%.

SourceTokyo University of Science·JournalThe Journal of Organic Chemistry·TypeExperimental study·DateJun 6, 2023

Small-molecule drug reverses neural effects of concussion

Researchers at UCSF discovered a small molecule called ISRIB that can reverse the neural and cognitive effects of concussion in mice, weeks after an injury occurred. The drug blocks the integrated stress response, which became chronically activated in damaged neurons, restoring normal spine dynamics and cognitive function.

SourceUniversity of California - San Francisco·JournalProceedings of the National Academy of Sciences·DateOct 10, 2022

Towards higher nanopatterning resolution with molecules that fill nanogaps better

A research group from Tokyo University of Science has discovered molecular features that govern the filling process at nanoscales, enabling finer resolutions in ultraviolet nanoimprint lithography. The findings provide valuable insights for guiding the selection and design of optimized resists for sub-10 nm resolution.

SourceTokyo University of Science·JournalNanomaterials·TypeComputational simulation/modeling·DateAug 8, 2022

Programmed cell death in cancer cells: Overcoming resistance through paraptosis-inducing compounds

Researchers from Tokyo University of Science developed novel complex-peptide hybrids that induce programmed cell death in apoptosis-resistant cancer cells through paraptosis. The compounds, syn-6 and anti-6, inhibit cell death by uncoupling mitochondrial calcium uptake and inducing cytoplasmic vacuolization, leading to cell death.

SourceTokyo University of Science·JournalBioconjugate Chemistry·TypeExperimental study·DateJul 11, 2022

New type of triterpenes discovered

Researchers have discovered a new type of triterpenes in fungi that don't require squalene, overturning current knowledge and offering a new approach to pharmaceutical science. This breakthrough opens up possibilities for creating more valuable compounds with anti-inflammatory, anti-cancer, and other properties.

SourceUniversity of Tokyo·JournalNature·TypeExperimental study·DateJun 1, 2022

The 2021 year in chemistry

In 2021, researchers made notable discoveries, such as the identification of pain-causing proteins in snake venom and the development of bite-sized protein structures that can be felt with the tongue. The year also saw significant progress in plastics recycling and molecular editing, which holds promise for medicinal chemists.

SourceAmerican Chemical Society·JournalChemical & Engineering News·DateJan 5, 2022