Researchers at Nara Institute of Science and Technology developed a practical, non-genetically modified brewing yeast that produces over nine times higher intracellular ornithine levels than the original yeast. The improved yeast retained normal brewing performance, making it suitable for value-added fermentation.
SourceNara Institute of Science and Technology·JournalJournal of Industrial Microbiology & Biotechnology·TypeExperimental study·DateJul 2, 2026
A recent study analyzed 7,301 metastatic breast cancer patients with MTAP loss, revealing younger age, higher TNBC cases, and BRCA1 mutations. The findings also suggest potential therapeutic agents targeting PRMT5 and MTA2 in MTAP-deficient cancers.
SourceImpact Journals LLC·JournalOncotarget·DateMar 14, 2023
A new study by CHOP researchers found that antibiotic-resistant Enterococcus enhances C. difficile virulence by modulating the gut environment, increasing toxin production and nutrient supply. This interaction supports increased colonization and persistence of C. difficile in the gut.
SourceChildren's Hospital of Philadelphia·JournalNature·DateNov 16, 2022
Researchers discovered a link between the astrocytic urea cycle and Alzheimer's disease memory loss. The study found that the urea cycle helps clean up toxic amyloid-beta aggregates, but its activation also causes the production of harmful byproducts, leading to neuronal death.
SourceInstitute for Basic Science·JournalCell Metabolism·TypeExperimental study·DateJun 22, 2022
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
Researchers have identified stearic acid and ornithine as indicators of coronary microvascular disease (CMD), a condition that damages blood vessels and causes decreased blood flow to the heart muscle. The study suggests that estrogen may also play a role in CMD development, particularly in postmenopausal women.
SourceCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign·JournalMetabolites·DateJun 30, 2021
Japanese scientists have discovered a mutant strain of sake yeast that produces 10 times the amount of the amino acid ornithine compared to the parent strain. Ornithine has been found to reduce fatigue and improve sleep quality, making it a potential pick-me-up for fans of traditional Japanese alcoholic beverage.
SourceNara Institute of Science and Technology·JournalMetabolic Engineering·DateAug 27, 2020
Researchers at the Weizmann Institute of Science and Hebrew University of Jerusalem reconstructed ancient protein sequences that may resemble those of early life forms. They discovered a way these primitive proteins could have progressed to form living cells, with positively-charged amino acids playing a crucial role.
SourceWeizmann Institute of Science·JournalProceedings of the National Academy of Sciences·DateJun 21, 2020