Articles tagged with Publishing Industry
Research finds PDX1 gene plays a tumor-promoting role in human PCa cells by influencing metabolic pathways. The study identifies PDX1 as differentially hypermethylated in prostate cancer tissues, contributing to its aggressive characteristics.
The extension of the partnership aims to refine SnapShot's performance for live manuscript submission, providing enhanced author feedback and guidance on data sharing. The collaboration also focuses on iterative product development, expanding assessment graphs to accommodate additional data policies.
A new gene catalogue provides comprehensive insights into premature aging disorders, highlighting the central role of genome maintenance and DNA repair pathways. The catalogue organizes genetic and clinical information for 56 syndromes and 160 distinct clinical entities, offering a valuable framework for future research.
Oncology services are often excluded from emergency health priorities, resulting in delayed diagnosis and treatment interruptions. Vulnerable populations, including women and children, face advanced disease stages due to delays in care.
The Oncotarget Editorial Board discusses the journal's evolving approach to scientific integrity, highlighting the importance of modern image forensics tools. The article emphasizes the need for independent analytical and AI-based tools in journal evaluation.
The study found that ATF5 plays a critical role in coordinating mitochondrial quality control and adaptive stress signaling in skeletal muscle. Absence of ATF5 resulted in increased muscle fatigability and elevated ROS production, highlighting its importance in maintaining muscle function with age.
Treatment with i.v. furosemide plus HSS significantly decreased serum levels of inflammatory biomarkers IL-6, sST2, hsTnT, galectin-3, and NT-proBNP. The study found that this combination therapy modulated some miRNA expression and was associated with reduced miR181b expression compared to furosemide alone.
The study found that immune checkpoint inhibitors significantly improved key clinical outcomes, including disease-free survival and distant metastasis-free survival. However, no clear improvement in overall survival was observed across studies, highlighting the need for careful patient selection and monitoring.
The article highlights the urgent need to modernize scientific record with AI-powered discoveries trapped in a predigital system. Top-tier research universities face $10-15 million annual subscription expenditures, while author-facing processing charges range from $5,000 to over $11,000 per article.
A new review analyzes how glioma classification research has evolved across clinical, molecular, and social domains. The study highlights the prominent role of DNA methylation profiling and advanced imaging techniques in molecular biomarker-based classification models, while finding social factors to be relatively scarce.
The COCOON trial found that a structured dermatologic prophylaxis regimen reduced moderate-to-severe dermatologic adverse events by half, with fewer grade ≥3 events and treatment discontinuations. This approach could improve tolerability and maintain dose intensity for EGFR-mutant non-small cell lung cancer patients.
Researchers found that older adults exhibit higher BOLD variability in cerebellar lobule VIIIb and greater modulation across task conditions. This modulation predicts performance in an age-dependent manner, with increased modulation linked to better performance in older adults.
The renewed agreement allows eligible researchers at participating UK institutions to publish unlimited articles across JMIR's portfolio of journals without APCs. This simplifies the publication workflow and increases equity for researchers at all career stages.
Dr Amy Shirong Lu joins JMIR Serious Games as Editor-in-Chief with extensive research on digital health technologies and their impact on physical activity and cognitive health.
Between 2021 and 2024, government organizations accounted for around one-tenth of the estimated $336 million spent on advertising to news websites publishing health misinformation. Pharmaceutical companies also made notable contributions.
Researchers found that targeting MD2 could reduce tumor growth in a mouse model of prostate cancer bone metastasis. High MD2 expression was associated with metastasis, immune suppression, and increased resistance to PARP inhibitor therapy.
A new study published in Aging-US found that plant-based dietary patterns are associated with slower epigenetic aging. The research analyzed data from two large cohorts and found that higher intake of plant foods was linked to decelerated biological aging.
Researchers found that the three-drug combination increased autophagosome formation and autophagic flux in uveal melanoma cells, killing them via enhanced autophagy. The study suggests a potential therapeutic approach for treating metastatic uveal melanoma, particularly in liver-targeted disease.
The company has announced an expansion of its innovative diamond open access (OA) model, Collective Pathway to Open Publishing, through agreements with Jisc in the UK and CAUL in Australasia. Six new journals will make their 2026 volumes open access without charging authors an article publishing charge.
The review emphasizes surgical excision as the cornerstone of curative treatment, with recommended margins depending on tumor risk stratification. Reconstruction should be individualized according to defect size, anatomic subunit involvement, and patient factors.
A systematic review of experimental studies found exergames to be associated with better mood outcomes, including reductions in tension and depressive symptoms. The evidence base remains small and heterogeneous, but the study calls for longer-term interventions and larger samples to determine the durability of benefits.
JMIR Publications and the University of Nevada, Las Vegas announce a new Flat-Fee Unlimited Open Access Publishing Agreement. The agreement eliminates financial obstacles for researchers, reducing administrative workload for library staff and ensuring research findings are available via immediate open access in JMIR's high-impact journ...
Over 11,000 Cambridge Scholars eBooks are now globally accessible through the Taylor & Francis eBooks platform. The partnership expands the reach of Cambridge Scholars titles, enhancing visibility and discoverability for rigorous academic scholarship.
A study found CREB5 regulates basal and SCL transcriptional programs and tumor-forming phenotypes in prostate cancer, suggesting a central role in aggressive prostate cancer. Disrupting CREB5-regulated pathways may improve therapeutic responses in advanced disease.
Researchers developed two neural network models predicting human biological age based on blood biochemistry and gut microbiota. The models demonstrated high predictive accuracy and explainability, holding potential for monitoring intervention effects in clinical trials.
A novel method for monitoring on-treatment disease burden in high-grade serous ovarian cancer uses tumor-informed breakpoints-spanning ddPCR, detecting superior sensitivity and specificity compared to real-time PCR. The approach may enable sensitive and specific detection of minimal residual disease and early relapse detection.
Dr. Sara Simblett brings expertise in digital health innovation, patient engagement, and technology integration to JMIR Neurotechnology. Her research focuses on improving access, quality, and outcomes of care through digital interventions.
Impact Journals is exhibiting at the AACR Annual Meeting 2026 in San Diego, showcasing recent publications and discussing collaboration opportunities. The meeting highlights the latest advances in cancer science and medicine, with a focus on research impact, ethical standards, and scientific integrity.
Researchers found that D, L-buthionine-(S, R)-sulfoximine (BSO) replicates the anti-obesity effects of sulfur amino acid restriction without causing bone loss in male mice. The study suggests BSO as a promising tool for dissecting the beneficial versus deleterious axes of sulfur amino acid biology.
A working group of scholars and experts proposes three principles - transparency, credit, and accountability - to form the foundation for responsible authorship. The principles aim to address issues of gift, ghost, and coercive authorship and promote a culture of transparency and accountability in scientific research.
A new study found that MYC amplification in metastatic prostate cancer is associated with reduced tumor immunogenicity, making it harder for the immune system to detect and attack the tumor. This reduction in immunogenicity was linked to poorer progression-free survival outcomes in patients with MYC-amplified tumors.
A new study reveals that p38 MAPK plays a key role in epigenetic regulation of fibrotic genes in lung fibroblasts, particularly in senescent cells. Pharmacological inhibition of p38 MAPK significantly reduced α-SMA and Col3A1 expression, suggesting a potential therapeutic target for treating age-related fibrotic diseases like IPF.
JMIR Publications has partnered with the University of Turku to provide unlimited open-access publishing, eliminating financial barriers and administrative hurdles for researchers. The partnership offers APC waivers for corresponding authors affiliated with the university, allowing them to publish in prestigious titles at no cost.
Prince of Songkla University and Taylor & Francis have partnered for a new open access agreement, supporting PSU's sustainable development mission and research impact. The partnership provides access to over 2,000 journals and eBooks, enabling PSU researchers to publish and share their work globally.
A new case report describes a large, calcified solid pseudopapillary neoplasm of the pancreatic head, emphasizing the importance of multidisciplinary evaluation and long-term follow-up for monitoring recurrence. The case underscores the diagnostic value of integrating imaging, histopathology, and immunohistochemistry.
A new metabolic theory proposes that a decline in glycolytic ATP production is the fundamental mechanism limiting lifespan. Species with an optimal rate of decline survived, suggesting that maintaining a stable glycolytic flux may support repair processes and tissue regeneration. The authors propose testing this hypothesis through expe...
A recent study found that higher IL6 levels are associated with increased mortality, while genetically higher IL6R levels reduce all-cause mortality through cardiovascular mechanisms. The researchers suggest that IL6R antagonism may be a potential strategy for preventing cardiovascular disease.
The article discusses recent advances in chimeric antigen receptor T-cell (CAR-T) therapy, highlighting its promise and remaining challenges. Next-generation CAR designs aim to improve specificity and reduce on-target/off-tumor toxicity, while addressing access disparities and equity issues.
A study profiles mitochondrial circular RNAs in Peripheral Blood Mononuclear Cells from young and old human cohorts, revealing that circMT-RNR2 levels are depleted in older cohorts and are involved in promoting the TCA cycle. Loss of GRSF1 reduces circMT-RNR2 levels, decreasing mitochondrial TCA intermediates and accelerating cellular ...
A new study examines the mechanisms, clinicopathological features, and management strategies of GI toxicity induced by targeted cancer therapies. The authors highlight the importance of close collaboration between oncologists, gastroenterologists, and pathologists to ensure accurate diagnosis.
Advances in Pollinator Research is a community-driven peer-reviewed journal championing research from underrepresented regions and taxa. It aims to find and amplify solutions to pollinator decline through transdisciplinary collaboration.
Researchers developed a new single-cell transcriptomic clock called Tictock to measure aging in specific immune cells. The study found that COVID-19 and HIV alter T cell composition and accelerate the biological age of naïve CD8 T cells, while long-term antiretroviral therapy stabilizes T cell proportions.
Researchers highlight polyploidy-induced senescence as a coordinated biological program that may drive aging, tissue repair, and cancer risk. Polyploidization in healthy tissues could help maintain organ structure and barrier integrity, but its instability can promote chromosomal instability and malignant transformation.
A new commentary raises concerns about editorial bias in scientific publishing, particularly in relation to COVID-19 vaccine safety and efficacy. The authors highlight the rejection of a case report and literature review that raised potential links between mRNA vaccines and rare blood cancers.
A case report investigates a woman's development of acute lymphoblastic leukemia and lymphoblastic lymphoma after receiving her second dose of the Pfizer-BioNTech COVID-19 mRNA vaccine, highlighting potential genetic and molecular mechanisms involved in disease pathogenesis.
Researchers found that an experimental compound SB-216 reduced the growth of pancreatic ductal adenocarcinoma cells by inhibiting oncogenic microtubules and mitochondrial function. This approach may reduce cancer cell adaptation and survival.
JMIR Publications introduces a new merit-based reward system, Karma, to recognize and reward high-quality peer reviews. The program provides incentives tied to the depth and rigor of feedback, ensuring that reviewers are properly honored for their contributions.
The expanded partnership strengthens researcher collaboration, increases open access opportunities, and fosters the impact of trusted knowledge. Researchers can discover and access relevant content through ResearchGate's Community Engagement Upgrade, while Taylor & Francis editors use new tools to grow their journals' communities.
A rare case of hyperammonemic encephalopathy caused by 5-fluorouracil (5-FU) chemotherapy has been reported, highlighting the importance of monitoring neurological symptoms in patients receiving 5-FU. The patient's symptoms resolved after stopping 5-FU and administering lactulose and intravenous fluids.
Early recognition and surgical management are crucial in treating necrotizing fasciitis of the head and neck, a rare but life-threatening soft tissue infection. The authors emphasize the urgent need for coordinated care, including immediate surgery, broad-spectrum antibiotics, and airway protection to reduce mortality rates.
The book sheds light on the often-ignored contributions of women in economics, highlighting their role as economic agents throughout history. Heggeness shares robust data and anecdotes about women who have thrived economically, from Taylor Swift to unsung heroes like Francis Perkins.
Pensoft has welcomed the Swiss Journal of Palaeontology (SJP) and Swiss Journal of Geosciences (SJG) to its portfolio. Both journals have transitioned to open-access models, leveraging Pensoft's ARPHA publishing platform for streamlined processes and increased visibility.
A rare diagnosis of a giant solitary neurofibroma in a 13-year-old boy was successfully treated with microsurgery. The tumor's location deep within the thigh along the sciatic nerve made it challenging to diagnose and treat, but careful surgical technique and postoperative care ensured optimal outcomes.
A new review proposes a two-stage model explaining how different determinants of aging interact to generate late-life disease. Early-life damage and late-life genetic activity are identified as key drivers of age-related illnesses.
Review of Clinical Pharmacology and Pharmacokinetics has transitioned to an open-access model, with all published content available on the new ARPHA website. The journal benefits from ARPHA's one-stop publishing solution, high-level integrations, semantic enhancements, and advanced metrics.
Research finds age-related DNA methylation alterations in sperm may contribute to autism risk in offspring. Advanced paternal age is associated with specific changes in sperm DNA, influencing early development in children.
Researchers found that CD47 knockdown improves glucose homeostasis and alleviates dyslipidemia in aged male mice by reducing visceral fat and enhancing brown fat tissue function. This breakthrough suggests CD47 as a key regulator of age-related metabolic dysfunction.
Dr Anita Bandrowski has been awarded the 2026 APE Award for Innovation in Scholarly Communication for her innovative work on open research infrastructure. Her efforts have improved scientific transparency and reproducibility through the use of persistent identifiers, increasing discoverability to over a million RRIDs.
PLOS has partnered with Charlesworth to expand access to publishing services for Chinese researchers and institutions, reinforcing its commitment to supporting open science globally. The partnership will enable PLOS to strengthen its presence in China through localized sales representation and innovative tools.
Aspiring nature writers will participate in a unique workshop and ecotour in the remote Smith Inlet, led by Lesley Evans Ogden. The program offers daily writing coaching and feedback sessions, with optional one-on-one coaching, and includes accommodations, meals, and wildlife tours.