Articles tagged with Research Impact
Researchers found a significant reduction in quetiapine use among nursing home patients (7%) and community-dwelling patients (15%), without signs of adverse effects. The intervention improved mental health outcomes and slightly reduced the risk of death for patients living in the community.
Disposable vape sales quadrupled in the UK between 2022 and 2023, contributing to e-waste accumulation. The technology contains valuable resources like lithium, but recycling is often difficult due to lack of clear instructions. Experts call for urgent reform of disposable electronics practices to protect the environment.
Cool-season turfgrasses face challenges under high temperature stress, leading to reduced growth and increased maintenance costs. Research proposes methods to enhance heat tolerance through molecular characterization and breeding strategies.
Clinical trials show decreased effectiveness of vancomycin in treating C. diff infection, with reduced cure rates and lower sustained clinical responses associated with antimicrobial resistance. The finding poses a significant concern for the management of C. diff infection, with only two recommended antibiotics available.
Researchers at NTU Singapore and Temasek Polytechnic develop a new, sustainable feed alternative for farmed Asian seabass, reducing reliance on wild-caught fishmeal. The single cell protein is cultivated from soybean processing wastewater, offering a promising solution to the aquaculture industry's environmental challenges.
Researchers at the Institute of Physical Chemistry of the Polish Academy of Sciences successfully unlocked a puzzle in vascular tissue engineering, providing important experimental evidence towards understanding and controlling sprouting angiogenesis in vitro. They developed new image-analysis protocols to determine key parameters gove...
Using AI software called SLEAP, scientists at Salk Institute are designing climate-saving plants with optimized root systems that can store more carbon. This approach enables researchers to analyze plant features and connect desirable traits to targetable genes, accelerating the development of carbon-capturing plants.
A new study found that better heart health in middle-aged Black women is linked to reduced cognitive decline and preserved brain function. However, this benefit was not observed among white women. The study suggests that taking care of one's heart may have a positive impact on brain function and overall well-being.
A new study reveals that a single hurricane can wipe out 5-10% of New England's total aboveground forest carbon through tree damage. The research team analyzed the impact of 10 powerful hurricanes on the region's forests and found that future storms could pose a significant risk to carbon offset programs.
A large-scale study revealed a profound link between dietary patterns and brain health, with a balanced diet associated with better mental health, superior cognitive functions and higher grey matter in the brain. The researchers suggest that gradual dietary modifications can lead to healthier food choices and improved wellbeing.
A groundbreaking study reveals an unsuspected role of the SNUPN gene in muscle cell function, identifying it as the causative factor for a debilitating muscular dystrophy. Researchers found that alterations in the Snurportin-1 protein encoded by the SNUPN gene disrupts muscle cell integrity and function.
Randles developed computational tools to harness supercomputers, creating highly precise simulations of biophysical processes. Her work has direct impacts on patient care, including simulations of 700,000 heartbeats and cancer cells moving through the body.
New research reveals that women entrepreneurs face significant biases in startup financing, with higher loan rejection rates and poorer credit terms. The study found that societies with greater women's empowerment actually exacerbate these gaps, suggesting a need for policy interventions to address the issue.
A study by Mount Sinai researchers has identified several pathophysiological mechanisms underlying perianal fistulae in Crohn’s disease. The findings highlight key transcription factor binding events and epigenetic phenomena that contribute to the higher rates of complications in African American patients. The research provides avenues...
Researchers discovered a novel brain network condition called 'explosive synchronization' that correlates with pain crises in sickle cell disease. This finding could lead to predicting and preventing severe episodes of pain, improving patient outcomes.
This study reveals that paclitaxel induces HBV reactivation by enhancing viral replication, activating transcription factor AP-1, and disrupting gut microbiota. PTX treatment promotes HBV core promoter activity and immune system dysregulation.
Researchers identified elevated MALAT1 levels in various blood cancers, correlating with adverse outcomes. MALAT1 promotes cancer cell proliferation, migration, invasion, and metastasis through multiple mechanisms.
Researchers assessed swimming performance and survival under stress to evaluate the effects of three compounds on health and lifespan in Caenorhabditis. The study found complex relationships among median lifespan, oxidative stress resistance, thermotolerance, and mobility vigor.
A forgotten poem by CS Lewis has been uncovered in Special Collections, revealing details of friendships between fantasy writers and medievalists at the University of Leeds. The poem praises the Gordons, a married couple who were close friends with JRR Tolkien and medievalist scholars.
Researchers have developed a pressure-alternating shoe insole that provides periods of rest to the soft tissues, thereby reducing the risk of diabetic foot ulcers. This innovative technology aims to mitigate the risk of complications from poor circulation and foot sores.
An interdisciplinary team led by Kaiyu Guan is using a combination of satellite remote sensing, in-situ measurements, and biochemical modeling to quantify nitrogen emissions from agriculture. The goal is to provide improved guidance for farmers on reducing nitrogen fertilizer use and alleviating air pollution.
A group of 350 scientists from over 60 countries call for a legally binding global treaty to prohibit the production of hazardous plastics chemicals and adopt science-based approaches. They advocate for an independent scientific body with robust conflict of interest policy and regional representation.
Researchers have discovered that non-native invasive plants can affect an ecosystem's sound patterns, potentially revealing physical and biological changes. By analyzing the acoustic landscape of areas invaded by these plants, the study aims to better understand the impact of invasive species on ecosystems.
A new study from Israel found that nearly 1 in 5 adults with congenital heart disease developed an abnormal heart rhythm during a five-year study. Those who developed arrhythmias had twice the risk of early death and increased hospitalization rates compared to those without irregular heart rhythms.
Researchers at University of California San Diego School of Medicine have identified hundreds of new genes associated with tobacco use disorder, including those linked to psychiatric and medical conditions. The study also identified hundreds of potential drug candidates that could help treat the disease.
A 23-year 'megadrought' in the western US is being studied by WVU researcher Steve Kannenberg to understand its effects on natural ecosystems, agricultural systems and human water resources. The research aims to identify areas with depleted groundwater and soil moisture, as well as assess carbon capture and storage in dryland plants.
The WVU Research Experience for Undergraduates program aims to solve real-world problems in Appalachia using mobile robotics. Students will conduct independent research in areas like drone navigation and swarming behaviors, focusing on enabling change with robotics tools.
Volunteers collected nearly nine tonnes of marine litter from beaches across the Seychelles between 2019 and 2023. The clean-ups, led by the University of Plymouth, demonstrate the potential of citizen science to address marine pollution challenges.
Researchers found that ketogenic diets reduced plasma levels of total Tau in females, mitigated elevations in plasma lipids, and improved circulating lipids. However, neither continuous nor intermittent ketogenic diets improved measures of cognitive or motor behavior in the TgF344-AD rat model.
A new study reveals that climate change could lead to a significant global GDP loss of up to 10% if the planet warms by +3ºC, highlighting the substantial costs of inaction.
Global disease burden rates dropped by 14.2% between 2010 and 2019, but the COVID-19 pandemic interrupted this trend, causing a 4.1% increase in disease burden in 2020 and a 7.2% increase in 2021.
The American Heart Association has awarded $15 million to researchers studying the role of inflammation in cardiac and brain diseases. The four-year project aims to better understand the body's response to inflammation and prevent or treat inflammation-driven cardiovascular diseases.
Researchers have developed an active learning strategy to accelerate the synthesis of high-performance engineered biochar with enhanced CO2 uptake. The approach nearly doubled CO2 capture performance, showcasing its transformative impact.
A new study models the impact of high thermal conductivity paper on power transformer performance and life. The research aims to improve transformer efficiency by reducing hotspot temperatures, potentially doubling or tripling lifespan. Researchers used Stampede2 supercomputer simulations to test the effectiveness of engineered paper.
A study found that social stress during adolescence in female mice leads to prolonged cortisol elevation after giving birth, similar to women exposed to adverse early life experiences. The researchers suggest alternative treatments may be more effective for postpartum depression.
A systematic review found a lack of reporting on ethnicity and underrepresentation of ethnic minority groups in MLTC intervention studies. Ethnic minorities are more likely to experience higher levels of socioeconomic deprivation, which contributes to the development of MLTCs.
A study claiming a decline in disruptive patents was based on a measurement error, researchers found. The correct analysis suggests that both disruptive and consolidating research are still needed to build upon existing knowledge and drive innovation.
A new study developed two machine learning models to quantify CD8+ cell positivity and classify the immunophenotype of cancer specimens in patients with non-small cell lung cancer. The models hold promise for identifying patients who may benefit from immunotherapy.
Researchers developed novel therapeutic bispecific antibodies targeting IgM and B-cell surface antigens, which directly inhibited cell proliferation via cell-cycle arrest and apoptosis in vitro. These findings suggest that anti-IgM/B-cell surface antigen-binding specific antibodies are promising therapeutic agents for B-cell malignancies.
A new scientific review published in Sustainable Production and Consumption explores how to accurately assess the carbon footprint of coffee farming. The study provides guidance on measuring green coffee's environmental impact, including identifying representative measurements and applying land use change modeling.
A research study investigates the role of TOR signalling in regulating seedling vigor, graft junction healing, and shoot-to-root communications. The study highlights the potential for improving grafting techniques and understanding plant communication to impact agricultural productivity and sustainability.
Scientists at CNIC have identified mechanisms by which anthracyclines damage the hearts of cancer patients, leading to cardiac injury. The study suggests that a protein-enriched diet may prevent muscle atrophy caused by anthracycline chemotherapy.
Researchers identified DlBGAL9 as pivotal in enhancing β-galactosidase activity for cell wall thickening and stress response in Longan. The study found that AGL61/80 regulates DlBGAL9, promoting early somatic embryogenesis and increasing longan resistance to heat stress.
A new study from Colorado State University suggests that transitioning to green wastewater-treatment approaches, financed through carbon markets, could save $15.6 billion and reduce CO2-equivalent emissions by 30 million tonnes over 40 years. The research explores the potential economic tradeoffs of switching to green infrastructure an...
New behavioral health intervention programs aim to increase physical activity and healthy eating among Americans. Researchers are testing innovative approaches, including integrating physical activity into schools and community programs, to address the growing diabetes epidemic.
Thorsten Hoppe and Jens Brüning received 2.5 million euros in funding from the European Research Council to investigate protein degradation and neural circuits of metabolic control, respectively. Their projects focus on preventing neurodegeneration and developing new drugs for obesity treatment.
Two new Review articles explore AI's application in early cancer detection, highlighting its potential to enhance diagnostic accuracy and improve treatment selection. The articles emphasize the need for a robust, multi-disciplinary approach to integrate AI into medicine.
A groundbreaking treatment approach that combines genetic testing with individualized drug testing on tumor samples has shown promising results in treating relapsed pediatric cancer patients. The study achieved an impressive 83% improvement rate, including Logan Jenner's successful treatment after his leukemia relapse.
A new study published in the Journal of the American Heart Association suggests that treating gum disease after a heart rhythm ablation procedure can lower oral inflammation and reduce the risk of AFib recurrence. Researchers found that an index measuring the severity of gum inflammation was associated with the return of AFib, highligh...
A new study has identified alpha-1-antichymotrypsin as a blood protein marker that can predict delayed recovery of concussion in children. The study found that children with low levels of alpha-1-antichymotrypsin were more likely to experience delayed recovery, highlighting the potential for early diagnosis and targeted treatment.
US pharmaceutical spending surged to $473.12 billion from 2011 to 2020, with diabetic medications accounting for a significant increase. The study found that antidiabetic agents were the most expensive therapeutic area, with Medicare and Medicaid contributing significantly to the costs.
A study of 156 severe COVID-19 survivors found that nearly two-thirds experienced persistent impairments after one year, including physical, respiratory, psychiatric, and cognitive problems. The study highlights the life-altering impact of SARS-CoV-2 on these individuals, many of whom required long-term acute care hospitalization.
Researchers discovered MIA-602's effectiveness against Doxorubicin-resistant acute myeloid leukemia (AML), demonstrating reduced cell viability and tumor volume. The study suggests MIA-602 as a potential alternative treatment approach for AML, potentially circumventing chemotherapy side effects.
Researchers suggest swapping red meat for herring/sardines could prevent half a million to 750,000 deaths from diet-related disease in 2050. Adopting this type of diet would be especially helpful for low and middle-income countries where these fish are cheap and plentiful.
A new study found that a remote team focused on education and medication management can improve guideline-directed-medical-therapy adherence in patients with type 2 diabetes. Patients who received education simultaneously with medication management demonstrated a higher rate of medication uptake.
A scientific review found only 128 studies investigating inter-connected drivers across infectious disease spread, biodiversity loss and climate change. Researchers highlight the need for interdisciplinary collaboration to identify win-win-win solutions and avoid unintended consequences.
A digital health platform with one-on-one telehealth coaches significantly improves patient adherence to pre-surgical preparation and post-surgical recovery guidance. Patients who used the platform had shorter hospital stays and lower risk of readmission compared to those who didn't use it.
A study from Colorado State University explores how human activity is altering the atmospheric water cycle, leading to changes in precipitation distribution and cloud formation. The research uses science fiction narratives to imagine possible futures and spark conversations around water management policies.
Vaping additives, particularly vitamin E, can damage the lungs by inhibiting gas exchange and lung stability. The study used Langmuir films to simulate the expansion and compression of the pulmonary surfactant, observing how the additive changed its properties and monitored changes as more were added.
The prevalence of problem and at-risk gambling in Massachusetts has remained steady since casinos were introduced in 2015, according to a statewide survey. The research team attributes this to the state's robust problem gambling prevention programs, including GameSense and voluntary self-exclusion.