A study published in Brain reveals that an increase in proteinaceous synthesis is linked to the degeneration of affected neurons in Huntington's disease. This finding could lead to the development of new therapies targeting this process.
The UTA project uses a national grant to improve transportation for older adults living in assisted-living communities across the Dallas area. The team analyzes data from various sources and conducts surveys to understand mobility needs, usage of available options, and potential barriers.
A phase I/II study of the Swedish vaccine candidate ETVAX found it to be safe and broadly immunogenic, inducing impressive immune responses in young children and infants. The vaccine showed high response rates among children aged 2-5 years and infants, with some even showing enhanced immune responses when given with an adjuvant.
Tropical Storm Fung-Wong is becoming more organized and symmetrical, indicating strengthening. The storm is forecast to strengthen to 55 knots within 24 hours before weakening rapidly near Taiwan.
Scientists developed a new approach to create metal-metal composites with a 3-D interconnected structure in thin films. The heat-driven process, called thin-film solid-state interfacial dealloying (SSID), has potential applications in catalysis, energy generation and storage, and biomedical sensing.
A McMaster University study found that virtual and mixed reality inferior to traditional physical models for anatomy learning. The research showed a 70% increase in accuracy with traditional physical models compared to digital media.
Scientists discover ancient legged snake Najash, which shed light on the evolution of snakes' flexible skull. The study reveals that snakes possessed hind legs for 70 million years before losing them.
The MIT researchers developed a bot equipped with artificial intelligence that can beat human players in tricky online multiplayer games where player roles and motives are kept secret. The bot uses deductive reasoning to identify friend or foe, ensuring victory over humans in certain games.
New research from Mongolia uncovers historic tool production and wild resource use, shedding light on premodern reindeer domestication. However, the study also highlights the devastating impact of climate change on modern reindeer herders' livelihoods and cultural heritage.
A new study reveals that integrating students' experiences of social oppression into the classroom strengthens entrepreneurial and STEM skills among underrepresented groups. Community college students who participated in a five-week social entrepreneurship program reported large gains in confidence and technology readiness.
A new system converts CO2, water, and renewable energy into ethylene under neutral conditions, offering a carbon-neutral alternative to fossil fuels. The improved catalyst reduces side products and increases selectivity for ethylene production.
Impaired SHMT2 expression impacts mitochondrial respiration and cellular growth, leading to age-related disorders. The study suggests that epigenetic processes contribute to aging by altering metabolic pathways.
The experimental HIV vaccine developed by Scripps Research and IAVI successfully elicited broadly neutralizing antibodies to at least two vulnerable sites on HIV. The test results suggest that researchers are one step closer to developing an effective HIV vaccine, a major goal of medical science.
Women from Appalachia are less likely to receive breast reconstruction surgery following a mastectomy due to lack of adequate care and patient education. Researchers highlight the need for better comprehensive breast cancer care, including access to reconstructive plastic surgeons.
Northwestern University researchers create a thin, wireless system that adds a sense of touch to virtual reality experiences, enabling new applications in social interactions, prosthetics, telemedicine, and entertainment. The device transmits touch patterns through miniature vibrating actuators embedded into a soft, flexible material.
NASA's Global Precipitation Measurement mission provides near-real-time rain estimates for Tropical Storm Sebastien, revealing moderate rainfall rates of up to 17.0 mm/hour east of the center. The storm is expected to become an extratropical cyclone in a couple of days and be absorbed by a cold front on Friday.
Researchers found that an inflammatory immune response and altered serotonin levels contribute to severe pregnancy-related depression. The study suggests that targeting this inflammatory pathway could lead to new treatments for perinatal depression.
Typhoon Kalmaegi is moving towards the northern Philippines, causing signal warnings in Luzon provinces. The storm has maximum sustained winds of 86mph and is expected to weaken rapidly as it enters the South China Sea.
Scientists from Osaka University have discovered a molecular 'light switch' that helps control vision in response to changes in light intensity. The enzyme Cul3-Klhl18 ubiquitin ligase regulates photoreceptor cell adaptation, and its inhibition may help treat conditions like age-related macular degeneration and retinitis pigmentosa.
A new UK study suggests that single motherhood is associated with lower verbal cognitive abilities in children, even after controlling for mothers' education and age at birth. Children who lived with a single mother before age 11 had lower verbal cognitive attainment than those whose parents stayed together.
Researchers discovered the most energetic gamma-ray burst ever recorded, emitting 1 tera-electron-volt of energy. This breakthrough confirms theoretical predictions and opens new avenues for understanding these powerful cosmic events.
The humidity digester, developed by Singapore researchers, can absorb more than four times its weight of water from humid air. It reduces relative humidity by 12 percent and generates a low current under ambient light, making it a potential replacement for air conditioners.
Artyom Yurov's research suggests the Universe may have quantum properties due to decoherence theory. The phenomenon states objects exist in multiple places until interacting with their environment, causing 'collapse'. This theory challenges traditional understanding of large-scale quantum effects.
A systematic review found that levels of agreement were low to moderate, highlighting the need for better experimental controls and more thorough reporting of outcomes in TCM research. New statistical approaches may also be suited to analyze Traditional Chinese Medical patterns.
A trial suggests that inducing labor at 41 weeks in low-risk pregnancies is associated with a lower risk of newborn death compared to expectant management. The researchers found no difference in adverse perinatal outcomes between the groups, but estimated that inducing labor could prevent one stillbirth for every 230 women induced.
A recent study by the Glioma Longitudinal Analysis (GLASS) Consortium discovered highly variable and patient-specific genomic alterations in diffuse gliomas over time. The research team characterized initial and recurrence samples from 222 patients, revealing that gliomas do not evolve consistently under cancer therapies.
The study reveals how bacteria's V1 motor converts chemical energy into mechanical rotation, similar to a well pump. Understanding this mechanism may lead to the development of highly efficient, man-made motors for implantable batteries or artificial electric eels.
A new energy harvester captures biomechanical energy from walking and converts it to electricity, powering wearable electronics without increasing the wearer's burden. The device generates an average power of 1.6 mW, weighing only 307 grams.
The Journal of Dental Research Centennial article 'The Evolution of Neuroscience as a Research Field Relevant to Dentistry' highlights novel insights gained through neuroscience research into pain, sensorimotor disorders and neural pathways. The study reveals the clinical relevance of these findings for diagnosis and management of diso...
Researchers identified genetic factors and parasite numbers that predict treatment success in cutaneous leishmaniasis. A small difference in parasite numbers makes a big difference in patient response.
The MAGIC telescopes detected the first-ever TeV photons from a gamma-ray burst, providing critical new insights into the physical processes at work in these cosmic events. The discovery sheds light on the mysteries surrounding gamma-ray bursts and their energetic emissions.
The study reveals the location of the most energetic outburst ever seen, sitting in a dense environment within a bright galaxy 5 billion light years away. The high-energy radiation was produced by a collapsing star at nearly the speed of light, creating a shock that triggered the gamma-ray burst.
Researchers at Carnegie Mellon University have developed a system called Video Event Reconstruction and Analysis (VERA) that can accurately locate a shooter based on video recordings from as few as three smartphones. VERA uses machine learning techniques to synchronize video feeds and calculate the position of each camera, with audio p...
A study published in Nature Communications found that while climate change increases iceberg production, it doesn't necessarily lead to increased iron input into the oceans. Ice samples from around the world revealed varying levels of iron content, with some ice containing up to a million times more iron than others.
Researchers at the University of Houston have developed a new hybrid device that can capture and store solar energy, offering promise for applications from power generation to distillation and desalination. The device achieves high efficiency harvesting and storage, with up to 90% efficiency and 80% recovered energy at night.
A systematic review and meta-analysis of nine longitudinal studies involving over eight million people found that increasing green areas can prevent premature all-cause mortality. The analysis revealed a 4% reduction in premature mortality per each increment of 0.1 in vegetation score within 500 meters of the residence.
Researchers identified a panobinostat-marizomib combination that effectively kills childhood brain cancer cells and counters genetic mutations. The study uncovered a previously unrecognized vulnerability in cancer cells, which may lead to new strategies against the disease.
Researchers found that fruit flies can build and update mental maps of their surroundings by linking visual features to compass neurons, allowing them to adapt to changing environments. This flexible mapping ability has implications for how other animals navigate in the wild and may even influence human navigation.
Researchers found that mice lacking an inflammation resolution sensor developed spontaneous obesity, heart disease, and shortened lifespan, indicating impaired inflammation resolution. This study sheds light on the sensor's integrative role in managing cardiometabolic health and inflammation-resolution processes.
A study from the University of California, Davis found a link between high levels of DDT and increased risk of obesity, insulin resistance, and metabolic disease in Asian Indian immigrants. Prior exposure to the pollutant may contribute to their higher rate of diabetes, even after migration to the US.
The new position paper provides practical guidance for managing postmenopausal osteoporosis, including easy-to-use algorithms that illustrate decision pathways based on absolute risk of fracture. The paper aims to offer the most appropriate interventions to patients, with a focus on targeting therapeutic interventions for low, high and...
Researchers found that circular extrachromosomal DNA in cancer cells dramatically amplifies mutant oncogenes, promoting aggressive behavior and resistance to therapy. This unique shape enables tumor cells to generate massive amounts of growth-promoting oncogenes and evolve quickly.
Research reveals that activated T helper cells can hinder HIV vaccine efficacy, as they migrate to mucosal tissues and express coreceptors that facilitate viral entry. This discovery highlights the need for careful consideration of T cell responses in vaccine development.
A team of scientists at ETH Zurich has developed a novel electro-opto-mechanical switch that can assess surroundings quickly and recognize people and obstacles. The switch uses plasmonics technology, which enables fast and compact switching with low losses.
The US Department of Defense has awarded the University of Kansas $2.5 million to advance seismic technology for detecting abandoned mines and tunnels. The research will focus on improving seismic data quality and detection efficiency, with tests conducted in known tunnels in the United States and abroad.
A study published in PLOS ONE found that over half of people would be willing to donate their personal data for research. The researchers developed a new questionnaire to explore individuals' motivations, which identified three key reasons: serving society, gaining personal benefits, and understanding data purpose.
The article highlights the importance of behavioral sciences in dentistry, expanding the understanding of oral health beyond 'disease' to a broader concept. Recent studies have shown promising results in employing cognitive behavioral therapy for managing dental anxiety and pain, as well as addressing oral health inequalities.
Researchers at City University of Hong Kong and Northwestern University have created a skin-integrated virtual reality system that can simulate touch with vibration wirelessly. The device is powered by radio frequency energy and can be controlled within a distance of one meter.
International researchers have found that most of the black carbon transported to the Atlantic Ocean is 'young' and likely results from recent forest fires. The study, published in Nature Communications, used radiometric dating and molecular composition analysis to quantify and characterize the black carbon flowing in the Amazon River.
A new robotic skin called ElectroSkin has been created, which can crawl across surfaces using artificial muscles and electrical charges. This innovative technology could lead to the development of soft robots for environmental monitoring, robot grippers, and wearable technologies.
Researchers at Oregon State University have developed an effective method to use underwater robotic gliders to measure sound levels over broad areas of the sea. The gliders can conduct repeated surveys of a region, providing real-time measurements of changing noise levels and helping scientists track ocean sound pollution.
Researchers identified 120 publications on occupant-centric control (OCC), but only 42 studies included field implementation. OCC's reliance on data raises technological and privacy issues, including secure data storage and whole-building approaches.
A new non-invasive microscopy technique uses quantitative phase microscopy and Raman spectroscopy to detect the activation state of macrophage cells and distinguish between different cell types. This approach enables high sensitivity at the single-cell level, revealing cellular heterogeneity and outlier behaviors.
A new study examined whether young children's verbal engagement with an onscreen interactive media character could boost their math skills. Children who had stronger emotional feelings for the character and talked more to the character about math had quicker and more accurate math responses during virtual game play.
Researchers found that reflecting on past sacrifices made by others for future generations can increase a sense of moral obligation to protect the environment. However, this approach has limited impact in increasing pro-environmental attitudes or motivations, and may even evoke feelings of unworthiness.
A new treatment using whittled sheep and dog bones has been found to be an effective alternative to metal pins for stabilizing fractured wings in pigeons. Pigeons with the bone implants were able to fly as well as before the operation, with no rejection of the implanted bones.
A population-based study found that only 1.3% of eligible patients received weight-loss medications, highlighting a significant gap in treatment access. The study also showed that phentermine was prescribed for over 75% of medication days, with most patients filling it for more than four months.
Researchers have identified 111,582 gene fusions in eight species, including humans, mice, and cattle. The ChiTaRS database provides a list of over 800 druggable fusions useful for personalized therapy in complex diseases like cancers and Alzheimer's.
An interdisciplinary team developed a simple method to identify the most accurate experts in groups by analyzing decision similarity. The research tested it successfully in various fields, including radiology and geopolitics, and found that the method accurately predicted accuracy.
Researchers from Peter the Great St.Petersburg Polytechnic University have successfully printed electrodes for miniature li-ion batteries using an inkjet printer. The proposed technological approach utilizes a lithium and manganese-enriched cathode material, which can lead to further miniaturization of these power supplies.