A new study by University of Chicago biologists found that Mediterranean mussels with existing genetic variation can adapt to declining pH levels in seawater caused by carbon emissions. The surviving population in the low pH environment differed genetically from others, suggesting a faster adaptation process if no new mutation arises.
SHAPEIT4 is a powerful computer tool that allows researchers to quickly identify haplotypes in hundreds of thousands of unrelated individuals. This enables the analysis of complex traits and disease risk with unprecedented accuracy.
Researchers at Universidad Complutense de Madrid have identified brain biomarkers for detecting Alzheimer's disease. A study found that patients with Mild Cognitive Impairment who develop dementia show increased and then decreased synchronization in brain regions, indicating cortical network dysfunction.
Researchers link various environmental factors such as food access, recreational opportunities, and natural amenities with engagement in weight management programs. The study also examines the impact of changes in the food, built, and socioeconomic environment on BMI in US counties.
Researchers tracked common noctule bat trajectories in Berlin to find that they mostly avoid built-up areas with artificial light. Instead, they use dark corridors like forests, parks, and watercourses for commuting and foraging.
A team of mathematicians has discovered a new phenomenon that generates a fluidic force capable of moving and binding particles immersed in density-layered fluids. This breakthrough offers an alternative to previously held assumptions about particle accumulation in lakes and oceans.
Researchers found that PBRM1 acts as a novel reader of the activated p53 pathway, suppressing renal tumor growth. Tumor-derived mutations in PBRM1 can disrupt this interaction, allowing cancer growth to occur.
Peregrine falcons have the fastest vision among birds of prey, registering up to 129 Hz blinks per second for high-light conditions. This exceptional visual acuity allows them to track fast-moving prey like flying birds and small mammals.
Researchers discovered a way to encode specific physical properties in materials by utilizing their 'memory' of past stresses. This approach allows for the creation of auxetic materials with enhanced mechanical properties, such as improved energy absorption and fracture resistance.
Researchers have developed an unbreakable security system that achieves 'perfect secrecy', protecting confidential data on public classical communication channels. The new technology uses silicon chips with complex structures to send information in a one-time key, making it impossible for hackers to intercept or recreate.
Dr. Shakirov and collaborators identified genes NOP2A, RPL5A, and RPL5B as crucial for controlling telomere length in Arabidopsis thaliana, a small flowering plant. This discovery provides new insights into the connection between ribosome biogenesis and telomere length control.
SIRT6, a longevity protein, plays a crucial role in burning and regulating liver fat metabolism. By activating PPAR-alpha, it promotes fat burning and protects against fatty liver and obesity-related damage.
Researchers from Forschungsverbund Berlin isolated and cultured different cell types from domestic cat corpus lutea tissue, enabling detailed characterization of their function. This breakthrough can aid in understanding the causes and mechanisms behind the longevity of corpus luteum in lynxes.
The MIPT team developed a new method for reinforcement learning with demonstrations, enabling rapid solution of hierarchical problems in Minecraft. This approach opens opportunities for applying reinforcement learning to real-world tasks like autonomous vehicle control and manipulator control.
A recent study has gained insight into the mechanisms of sarcopenia, a condition characterized by muscle wasting and strength loss in older adults. Researchers identified changes in muscle cells and molecules that may explain why some people develop sarcopenia while others do not.
Thyroid cancer rates in the US have stabilized since 2014, with a decline in new cases per 100,000 people from 14.7 to 14.1 between 2009 and 2016. The rise in thyroid cancer was largely due to increased screening and imaging over the past three decades.
Research finds impaired motor skills in preschoolers and lower IQ in middle childhood for boys whose mothers were severely overweight during pregnancy. A nurturing home environment can lessen the negative effects of obesity on child development.
The penKid biomarker accurately predicted acute kidney injury (AKI), multiorgan failure, and mortality in unselected sepsis patients at presentation to the emergency department. Increasing penKid levels indicated worsening kidney function, enabling timely treatment decisions that improve outcomes.
Researchers at CNIC have identified molecules that act as an 'airbag' protecting cells from mechanical stress. The study shows how these molecules coordinate changes to protect the cell and prevent damage. Altering their activity could lead to new therapies for diseases related to mechanical stress.
A recent study found that the proportion of high-strength painkiller poisonings among children resulting in emergency hospital admissions has increased. The opioid crisis is affecting young people, with suspected suicide cases among under-19s being a major factor.
A new study by McGill University researchers found that APOEε4 carriers have greater levels of tau tangles in memory centers, even after controlling for amyloid plaques. The study provides evidence that the gene's risk of dementia is related to both hallmark pathologies of Alzheimer's disease.
A novel therapeutic target for promoting neuroprotection has been identified in the lumbar circuit below a spinal cord injury, suggesting potential hope for restoring motor function. The discovery uses animal models to show that neuromodulation of interrupted lumbar motor circuits with neurotrophic therapy improves locomotor performance.
A pilot study will examine the utility of quantitative ultrasound methods for assessing vaginal birth-induced pelvic floor injury and recovery in pregnant women. The researchers aim to develop noninvasive diagnostic methods that can predict long-term pelvic floor dysfunction.
MIT engineers develop new laser ultrasound technique that remotely images inside a person, eliminating the need for direct contact. The method uses sound waves generated by a laser to create images comparable to conventional ultrasound, with potential applications in imaging infants, burn victims, and accident survivors.
Patients transplanted with hepatitis C-positive donor hearts had comparable outcomes after one year compared to those receiving hearts from disease-free donors. The study suggests using such hearts can expand the donor pool, reduce wait times and improve patient survival rates.
HDR images offer a wider dynamic range of luminance, simulating human eye adaptation to various lighting conditions. A new method stabilizes the camera response function while coupling colour channels, producing artefact-free results.
Researchers develop method to convert spherical lipid vesicles into 2D nanosheets and back again in a controlled process. The reversible conversion enables the creation of ultra-thin flexible nanosheets with valuable properties for biomembrane studies and applications.
Researchers at NIST have developed methods to measure the efficiency of five single-photon detectors, which are used in various applications such as optical communications and astrophysics. The study provides a tool for verifying future detection standards and aims to improve accuracy and reliability in these devices.
Bern researchers have identified the neurons responsible for rapid eye movements (REM) during sleep, a characteristic of paradoxical sleep with high dream activity. The discovery was made by a team of scientists who found that activation of these neurons causes rapid eye movement and can be used to study the function of this phenomenon.
Researchers developed a mathematical model to predict cancer drug side effects by analyzing genetic mutations in the UGT1A1 enzyme. The model was able to accurately predict the ability of UGT1A1 mutants to metabolize anti-cancer agents, offering potential for personalized treatment and reducing severe side effects.
A German high school's flexible scheduling system, which allows students to start school later, has been shown to improve their sleep patterns and ability to concentrate. The study found that students who started school later slept more soundly and were better equipped to handle coursework.
People with obesity produce more carbon dioxide due to higher metabolism and food consumption, contributing to 1.6% of global man-made emissions. Managing obesity can favorably affect the environment, with potential implications for healthcare and environmental policies.
Researchers worldwide can access cutting-edge tools and expertise at the Sandia Low Temperature Plasma Research Facility, enabling proof-of-principle studies on a wide range of plasma behaviors. The 5-year project, funded by DOE's Office of Science, fosters collaboration between Sandia and other institutions.
A new project aims to create targeted cancer drugs that use small molecules and immune system activators, potentially treating tumours less aggressively. Researchers from 14 European partners will work together to develop prototypes for future tumour therapies.
Researchers at IKBFU identified spirocycles as a building block of organic molecules with potential for medical chemistry development. These naturally occurring compounds, such as artemisinin, exhibit biocompatibility and have inspired the synthesis of new medicinal compounds.
Scientists have observed people developing Type 2 diabetes due to liver fat over-spilling into the pancreas. A study showed that individuals can reverse the condition through diet and weight loss, with nearly nine out of ten participants achieving remission.
Research suggests that longer exposure to obesity and earlier development of obesity are linked to an increased risk of type 2 diabetes. Women who experienced rapid weight gain from young adulthood had a higher risk of developing the disease compared to those who remained stable.
A study by Dr Brianna Verigin found that nearly half of all lies are told by a small number of prolific liars, who use their charm and words to deceive others. These expert liars prefer face-to-face interactions and often lie to close family members and colleagues.
A new study by Swansea University found that women who value their own health are more likely to benefit from physiotherapy treatment for pelvic floor dysfunction. The research suggests that supporting patients to develop positive health values can enhance attendance and outcomes, potentially reducing the need for surgical intervention.
Researchers create a new type of optical metasurface that imposes phase modulation on reflected light, leading to unidirectional light propagation. The metasurface enables nonreciprocal light propagation in free space with unprecedented large temporal modulation frequency.
Researchers at HKU have identified a protein, OsACBP2, that enhances grain size and weight in transgenic rice by 10%, increasing biomass and oil content. This technology has the potential to boost grain yield and composition, addressing food security challenges.
Research shows adolescents struggling with mental health issues have distinct neural connections that affect cognitive control and attention. The study provides new insights into the brain development of adolescents with mental health problems, potentially informing diagnosis and treatment.
A high-resolution geophysical survey has confirmed the ideal site for drilling a 1.5-million-year-old ice core in East Antarctica's Little Dome C area. The drill site, located 40 km away from Concordia Station, will provide valuable information on the Antarctic climate and greenhouse gases during the Middle Pleistocene Transition.
Researchers at Universidad Complutense de Madrid developed an AI-powered algorithm that uses deep learning to detect irregularities in rice labelling. The algorithm achieved precision models between 93 and 99%, showing potential for future applications in the food industry.
Researchers aim to characterize coal dust properties and investigate biological effects of nano-coal dust on lung cells, using a 3D lung-on-a-chip device. This study seeks to understand the toxicity of nano-coal dusts and their impact on human health.
A brief disruption to a molecular pathway in mice before birth compromises adult immunity to rotavirus, preventing antibody responses and interfering with gut cells that support antibody production.
A study published in Nature Ecology & Evolution finds that rare species are organized in groups to coexist with more abundant species, avoiding competitive pressure. This organization may be a key to understanding the persistence of biodiversity in ecosystems.
Scientists at Rice University have developed new methods to characterize the influence of turbulence on space weather. They discovered that bursty bulk flows cause big ripples in plasma, leading to oscillations called buoyancy waves. These waves play a role in the formation of auroral structures and magnetospheric substorms.
Kyoto University researchers have developed a new 'tumor-on-a-chip' device that can better mimic the environment inside the body. The device allows for the growth of tumor cells and blood vessels in three dimensions, enabling scientists to test potential cancer fighting drugs more effectively.
Researchers at LMU have discovered that inhibition of a specific enzyme can effectively prevent heparin-induced thrombocytopenia (HIT), a potentially life-threatening condition. The study shows that Btk inhibitors can block platelet activation and prevent the formation of harmful clots, offering a new promising therapeutic option for t...
Researchers found that luxury purchases can lead to feelings of inauthenticity, reducing consumer enjoyment. Consumers who feel they don't deserve their luxurious items are more likely to experience impostor syndrome.
Cynthia Ju, a UTHealth scientist, has been awarded $3.6 million in NIH grants to investigate molecules linked to liver injuries. Her research aims to identify potential therapeutic targets to enhance or block the activity of these molecules.
A team of researchers observed regular oscillations in the populations of rotifers and green algae over a period of one year, corresponding to more than 50 cycles. The oscillations were repeatedly interrupted by short periods without discernible external influences, but always returned to their normal rhythm on their own.
Researchers at IKBFU create novel laser optic manufacturing process utilizing rare-earth metal ions of ytterbium and its oxide, reducing production costs. The new powder can generate powerful red laser radiation and improve image quality in night-vision goggles.
This observational study found that the age-sex-adjusted proportion of US adults with diabetes was 12.1% for non-Hispanic whites, 20.4% for non-Hispanic blacks, 22.1% for Hispanics, and 19.1% for non-Hispanic Asians. Notably, Hispanic and non-Hispanic Asian subpopulations showed significant differences in undiagnosed diabetes rates.
A new educational outreach training package has shown effectiveness in managing respiratory diseases like COPD and asthma in Brazil. The Practical Approach to Care Kit (PACK) provides basic, cost-effective ways to diagnose and treat these common, severe diseases.
A genetic risk score can identify individuals at a 3-fold increased risk of developing ischaemic stroke, a devastating condition. This scoring system may require more intensive preventive measures than current guidelines recommend.
A study found that popular gym chains offer tanning beds in over 78% of their locations, despite public health warnings about the dangers of indoor tanning. Gyms are undermining health by marketing tanning beds to physically active people who are at increased risk for melanoma.
Researchers have identified a new subtype of satellite cells that can regenerate muscle tissue without the transcription factor PAX7. This discovery could lead to new gene therapies for people with muscular dystrophy, such as Lavin, who has a rare genetic mutation preventing her from producing this protein.
Lemon, a new framework, enables faster extraction of biological information from large datasets, enhancing drug development. The software can process PDB data in minutes, reducing time from hours to seconds.