A new study from the University of Chicago suggests that smoking may be linked to dementia through a previously unmapped route between the lungs and brain, involving pulmonary neuroendocrine cells and exosomes that disrupt iron balance in neurons.
Researchers developed a nanophotonic platform to generate quantum optical Stokes skyrmion states with controlled topological invariant, eliminating the need for post-selection. This enables robust morphing of quantum information into free-space.
Scientists at NTU Singapore found that glycerol-3-phosphate acyltransferase (GPAT) amplifies α-synuclein toxicity by altering fat metabolism in brain cells. Targeting GPAT activity may offer a new strategy for treating Parkinson's disease.
Researchers are evaluating the state's domestic violence resources to better support survivors and prevent further abuse. Through a $257,384 grant, UCF faculty are analyzing data from various sources and surveying organizations that provide domestic violence services.
The Global Flourishing Study dataset, spanning two waves and 200,000 participants across 22 countries, is now publicly available. Researchers can access the data without pre-registration, expanding the study's impact on understanding human flourishing.
Researchers found that auxin's partner proteins serve as internal plant 'thermostats' that directly sense temperature and change genetic programs to direct root growth accordingly. This discovery could lead to engineering plants that withstand extreme temperatures, protecting crop productivity under challenging conditions.
A comprehensive review of artificial intelligence in steel modular structures' generative design reveals a shift from rule-based automation to integrated, data-driven solutions. The study proposes future directions for hybrid knowledge-data integration models and practical engineering deployment.
A study published in Cell Reports reveals a two-phase model explaining the origin of childhood B-ALL, involving hyperdiploidy and subsequent malignant transformation. Hyperdiploidy causes chromosomal instability, delaying cell differentiation and allowing rare clones to persist without triggering leukaemia.
Using new genetic markers, fruit breeders can predict flower sex type and seedlessness in muscadines and other grapes with high accuracy. The approach will save time and resources in developing new grape varieties, including the major challenge of creating flavorful seedless muscadines on self-pollinating vines.
Researchers at the University of Minnesota Medical School have developed a new method called PARTAGE that provides a clearer picture of how the genome is regulated and disrupted in diseases like cancer. The method allows for the measurement of three key features from the same sample: DNA duplication, genomic alterations, and gene activ...
Researchers developed a halide-perovskite metasurface strategy using dual quasi-bound states in the continuum (q-BICs) to overcome pump absorption and radiative efficiency limitations. The system achieved an external quantum efficiency of up to 98.8% and cooled materials from room temperature to -201 °C.
A recent genetic study analyzing DNA from 2 million people found that similar chunks of DNA are associated with both psychiatric disorders like depression and PTSD, as well as various physical ailments. This discovery could lead to more effective treatments that address both mental and physical health.
Researchers developed a flexible optical fiber that can be steered into the larynx to destroy hard-to-reach tumors, expanding outpatient laser treatment options. The device successfully reached 81% of targets in tests with a 3D-printed replica of a human larynx.
The Chancellor’s Innovation Fund Awards support cutting-edge research and development projects across various fields. Faculty recipients will use the funding to refine their technologies, build prototypes, and assess market opportunities. The awards aim to bridge publicly funded academic research with private financing, fostering entre...
A new enzyme from a fungus cultivated in sugarcane bagasse or wheat bran can promote cellulose pulp bleaching. The xylanase facilitates the removal of xylan fractions associated with residual lignin, increasing brightness and efficiency in subsequent stages of pulp processing. This non-toxic alternative reduces chemical load and has gr...
A 289-million-year-old mummified reptile has provided scientists with a unique window into the evolution of breathing and movement in ancient reptiles. The study found that the reptile's respiratory system is similar to that of modern reptiles, birds, and mammals, suggesting an efficient mechanism for respiration.
A new study found that targeted, case-based learning improved provider confidence and identified critical unmet educational needs in menopause care. Clinicians reported high satisfaction with the program and noted anticipated changes in clinical practice, such as increased comfort initiating treatment.
Researchers found that blocking clusterin, a molecule linked to stress and tumor growth, slows tumor growth signals and makes the cancer more responsive to cisplatin. The study's findings offer a possible strategy for treating cervical gastric-type adenocarcinoma, one of the most aggressive non-HPV associated cervical adenocarcinomas.
A national Canadian study found that older adults who are socially connected, physically healthy, and spiritually engaged are significantly more likely to experience complete mental health. Social support emerged as one of the strongest predictors, doubling the odds of achieving complete mental health.
Researchers are diversifying CAR therapy to overcome limitations, exploring engineered cell platforms like NK cells, γδ T cells, and macrophages. This expansion could treat a broader range of diseases, including lupus, infection, cardiac fibrosis, and senescence-related disorders.
A study reveals improved quality of mammal species descriptions from temperate regions, with authors from wealthy countries using more advanced techniques. The study, supported by FAPESP, analyzed 1,116 new species descriptions between 1990 and 2025.
A new study from University of Florida finds that employee perfectionism impact depends on alignment with supervisor's expectations and clarity in understanding. When employees' standards match supervisors', they experience less uncertainty, better performance, and higher job satisfaction.
Researchers have discovered a new species of glassfrog in Ecuador named after Neisi Dajomes, the first Ecuadorian woman to win an Olympic gold medal. The Dajomes glassfrog has uniformly green skin with a pebbly texture and a white membrane covered in light-reflecting cells on its underside.
Scripps Research scientists develop a new approach to building branched molecular structures, overcoming a technical obstacle that limited chemists' ability to assemble complex molecules. The method, using metal hydride selection, produces more than 50 new branched compounds with an unusually high degree of control.
A new study found that exposure to PFAS may weaken the immune system in adults, raising concerns about long-term health effects of these widely used chemicals. The research highlights the importance of reducing PFAS levels in drinking water to protect public health.
A small Dutch survey found that more than half of veterinarians believe they will see cases of animal abuse by falsification, akin to Munchausen syndrome by proxy. This recognition is alarming and warrants further investigation into animal welfare practices among veterinary professionals.
A new study by Mass General Brigham reveals that long-term exposure to excess weight is a stronger predictor of cardiovascular disease risk than BMI at a single point in time. Younger individuals with high cumulative exposure to excess weight are particularly at increased risk.
Research reveals strong global link between ancient subduction zones and formation of rare earth element deposits and carbonatites. Ancient tectonic processes are critical to locating economically viable rare mineral deposits.
Researchers have successfully initialized and detected nuclear spin states in a europium-based molecular crystal using laser light, achieving nuclear spin quantum coherence with a lifetime of up to two milliseconds. This breakthrough paves the way for scalable quantum computers and atomically precise qubit registers.
Researchers at Binghamton University have created a talking robot guide dog system that determines ideal routes and guides visually impaired users safely to their destinations. The system offers real-time verbal feedback and provides situational awareness, significantly enhancing the user experience.
A new study reveals that subsidence is a major driver of coastal flooding along Java Island, with rates of up to 15 centimeters per year. Groundwater withdrawal and agricultural water use are identified as key culprits, highlighting the need for active monitoring and mitigation.
Anglerfish species use lures for both attracting prey and signaling potential mates, with bioluminescent lures appearing around 34-23 million years ago. Researchers analyzed over 100 species to study the evolutionary history of lures, tracing changes from motion-based to glowing lures.
Researchers have developed light-driven nanorobots that can track down and collect bacteria, perform rapid 90° turns and selectively capture bacteria. The nanorobots enable controlled interaction with the microscopic world, opening possibilities for microbiology, biomedical research and targeted manipulation at the microscale.
The S2419 BioFront study aims to enroll over 700 patients with advanced renal cell carcinoma and test the safety and efficacy of a CBM588 capsule as part of an immunotherapy-based treatment. The trial seeks to improve outcomes for patients by leveraging the gut microbiome.
A new study reveals that human transformations in land cover have a substantially greater influence on landslide fatalities than physical factors, particularly in low- and lower-middle-income nations. This research highlights how increasing human pressure on nature worsens the vulnerability of socioeconomically disadvantaged people.
A new study found that breastfeeding practices vary significantly between urban slum and non-slum areas in India. Urban slum mothers tend to start breastfeeding earlier, while non-slum mothers are more likely to breastfeed only breastmilk for the first five months.
A Phase I clinical trial of a human monoclonal antibody for Lyme disease demonstrates its safety, tolerability, and pharmacokinetics. The treatment, TNX-4800, provides lasting serum concentrations and has the potential to offer passive immunity against the disease.
The European Association of Nuclear Medicine (EANM) has joined the EMUC26 congress to promote nuclear medicine expertise in urological cancers. The event will bring together healthcare professionals from various disciplines to discuss current practices and emerging innovations.
Research reveals inflammation in the GI tract changes how nerves are arranged, affecting intestinal muscle contractions. A protective stress response pathway helps neurons survive, preserving their structure and potentially offering a way to curtail persistent symptoms associated with IBD.
A Northwestern University study found that apolipoprotein B (apoB) testing is more effective and cost-efficient than standard cholesterol tests in guiding treatment and preventing heart attacks and strokes. The study suggests that apoB-guided care can improve population health and save lives at a lower cost.
A new study by the University of Ottawa found that emojis can negatively affect perceptions of competence and appropriateness in professional settings. The researchers discovered that using positive emojis with negative messages can create a sense of dishonesty, while negative emojis can lower overall competence perception.
Researchers at the University of Texas M.D. Anderson Cancer Center have identified a way lung cancer cells evade radiation therapy and developed a strategy to overcome this challenge using a DHODH inhibitor. The study found that inhibiting DHODH with leflunomide can help overcome radiation resistance by promoting ferroptosis, allowing ...
A recent study published in the Journal of Nutrition Education and Behavior found that a Food is Medicine and food literacy education program improved food-related knowledge and practical skills among rural, uninsured adults with type 2 diabetes. The Fresh Start FIM + Food Literacy intervention showed significant overall improvements i...
A recent study found a decline in long-term opioid prescribing in the US between 2015 and 2023, with a 24.3% decrease in patients receiving extended therapy. However, approximately 4.2 million US patients still received opioids for 90 days or longer in 2023, indicating the need for improved treatment models for chronic pain management.
The VCU Massey Comprehensive Cancer Center has completed the inaugural funding cycle of its collaborative drug discovery program with the Sanford Burnham Prebys Medical Discovery Institute. Two projects have received $50,000 each to advance innovative cancer drug discovery efforts.
Researchers at Terasaki Institute for Biomedical Innovation develop a smart contact lens that monitors intraocular pressure in real time and delivers treatment. The technology has shown promising results in preclinical models and aims to improve quality of life for patients with ocular diseases.
A study published in Cancer Research has identified DPY30 as an epigenetic target that can sensitize pancreatic tumors to immunotherapy. By modulating DNA replication stress, DPY30 promotes the addition of activation signals at stressed replication forks, supporting cancer cell survival and proliferation.
A meta-analysis of millions of community-dwelling adults found that regular physical activity, less sedentary time, and appropriate nightly sleep (7-8 hours) were associated with a lower subsequent risk of dementia. Conversely, too little or too much sleep was linked to an increased risk, highlighting the importance of optimal sleep du...
Researchers warn that a securitized response to global biodiversity loss could lead to poorly targeted actions and policy. They highlight concerns over migration claims and call for evidence-based, non-securitised policy.
Researchers have discovered that lithium dendrites in batteries are unexpectedly strong and brittle, causing short circuits and safety risks. The findings suggest that future battery design must change to improve safety and reliability of high-energy storage systems.
Researchers have developed a new MRI technique that can track transplanted stem-cell-derived heart cells over long periods. This method allows scientists to visualize where transplanted cells survive, helping to improve therapies for patients with heart damage.
Scientists have successfully controlled heat transport in molecules by replacing a single atom with heavier halogen atoms, significantly reducing thermal conductance. This breakthrough opens up the possibility of independent control over thermal and electric current in molecular materials.
A new method creates flexible microsupercapacitors on vegetable-tanned leather using a CO2 laser, enabling eco-friendly and durable energy storage. The technology has potential applications in wearable electronics, smart clothing, and skin-mounted sensors.
Researchers found cut marks on turtle shell fragments suggesting Neanderthals carefully butchered and cleaned the shells, which may have been reused as small containers or scoop-like implements. The study sheds new light on Neanderthal ecological flexibility and survival strategies.
Dr. G. Michael Harper, a renowned mentor and educator, receives the Dennis W. Jahnigen Memorial Award from AGS for his transformative work in geriatrics education. He has developed innovative programs and standards that train healthcare professionals to care for older adults.
A new study from Northwestern University and the Chicago Botanic Garden found that some cultivated plants, such as black-eyed Susan and foxglove beardtongue, can attract pollinators at similar rates to their wild counterparts. This research provides a middle ground for gardeners who want to support pollinators without going fully wild.
A new JACR study suggests radiology departments should optimize use of linens and disposable supplies to reduce environmental impact and costs. The study found that linens (35%) and other single-use supplies (34%) accounted for most of ultrasound's greenhouse gas emissions.
A study reveals that Atlantic mangrove fiddler crabs are settling into temperate salt marshes along the southeastern US coast due to climate change. The species is expanding its range northward, with some populations reaching as far as South Carolina, and may soon spread to North Carolina.
Researchers have identified drug candidates that reverse disrupted behaviors in zebrafish carrying mutations in specific autism risk genes. The study highlights the importance of stratifying or subgrouping autism risk genes to identify potential drug candidates using a precision medicine-based approach.
A new study found that male, married Canadians with social support, healthy habits, and excellent health are more likely to experience high levels of emotional, psychological, and social well-being. Social support was a key factor associated with flourishing mental health among older adults.