A recent national study analyzing over 11,800 adolescents found that substance use increases steadily with age, with 38% reporting use by age 16. The study highlights notable differences between boys and girls, particularly in polysubstance use patterns.
The American College of Lifestyle Medicine's (ACLM) Lifestyle Medicine Residency Curriculum has earned the 2026 AAMSE Profiles of Excellence Award. The curriculum, launched in an effort to address a gap in physician training, integrates lifestyle medicine into routine clinical training and emphasizes behavior change counseling and real...
Aging cells become more susceptible to ferroptosis due to elevated levels of acid ceramidase, a previously targeted therapeutic candidate. This vulnerability can be passed to neighboring cells, impacting overall tissue health. The discovery offers new hope for supporting healthy aging and treating age-related diseases.
Researchers have developed an AI-powered framework that combines multiple AI technologies with automated experiments to accelerate the discovery of advanced energy materials. The '4th+ paradigm' approach enables near-atomic-level accuracy in predicting material properties and rapidly analyzing experimental data.
Revolver Therapeutics, a spin-out company from the University of Bath, has won the Health category of the Royal Society of Chemistry's Emerging Technologies Competition with its proprietary discovery platform. The platform generates and tests millions of constrained peptide drug candidates directly inside living cells, selecting for mo...
New research reveals that tiny fly larvae have evolved specialized air sacs that allow them to survive in deep freshwater environments without collapsing under pressure. These adaptations enable precise movement and breathing through their skin, contradicting long-held assumptions about insect physiology.
Researchers have identified a new strategy to prevent T cell exhaustion and boost immunotherapy by blocking MEK signaling. This approach has shown promise in lab models, enabling T cells to persist under harsh tumor conditions. However, the effectiveness of this treatment may vary among patients due to the complexity of T cell exhaustion.
A new bio-based conductive hydrogel platform is presented to preserve biomembrane activity and enable sensitive detection of organophosphate pesticides. The developed biosensor demonstrated stable operation, retaining 85.8% of its original electrochemical response after seven days.
Researchers at NUS CDE developed compact memristive radio-frequency switches that can be integrated onto gallium nitride microchips. The switches retain their settings without continuous power, reducing chip size and power use.
Researchers at the University of Washington School of Medicine discovered that environmental bacteria can acquire and transfer antibiotic resistance genes to disease-causing bacteria in human lungs. This mechanism, previously unknown, could lead to rapid development of extreme antibiotic resistance. The study highlights the potential f...
A new study published in Nutrition Reviews identified popular menu items high in sodium and sugar, providing a starting point for creating healthier menus. School officials can use these findings to develop recipes that adhere to updated guidelines while still serving students' favorite foods.
Gert Aarts, a renowned physicist, has been awarded 1.58 million euros in funding from the Wübben Foundation Science to establish an Advanced Professorship at Bielefeld University. He will focus on linking theoretical physics with machine learning and expanding research on strongly interacting matter.
Researchers developed a water-retaining hydrogel electrode that stabilizes insect antennae, enabling odor sensing for up to seven hours. The biohybrid sensor supports disaster response, environmental monitoring, and hazardous chemical detection.
A team developed a platform for on-demand design of synthetic plant immune receptors (SPIRs) that recognize proteins from diverse plant pathogens. SPIRs were designed using AI-assisted tools and optimized using a high-throughput platform, demonstrating effective resistance to certain viruses and bacteria.
A study published by the American Psychological Association suggests that accepting uncertainty in career development can lead to greater meaning in work. Researchers found that individuals with 'career wisdom' were more likely to report a stronger sense of meaning in their work, predicting higher job satisfaction and well-being.
The University of Tennessee has received a $20 million NSF grant to establish ATHENA, a national network of AI-powered laboratories for accelerating scientific discovery. The initiative aims to revolutionize materials discovery by accelerating design, synthesis, characterization and autonomous optimization of advanced materials.
A new form of physical computing has been demonstrated using a few hundred microscopic particles oscillating in a liquid. The system harnesses collective dynamics to perform computations, reducing the need for precise control and increasing efficiency.
Researchers propose a multiple-moon-aided Jovian capture method utilizing solar gravity perturbation (SGP) to reduce velocity increments. The study uses four dynamic models and computes datasets to analyze the mechanism of SGP, revealing its influence on perijove radius change.
The study reveals how the encephalomyocarditis virus (EMCV) hijacks host ribosomes and translational factors to translate viral genes while blocking host gene translation. Targeting this mechanism could lead to new treatments for EMCV and similar viruses like poliovirus.
Researchers have developed a mathematical model that predicts relationship outcomes by accounting for forgetting rates, attraction levels, and reaction patterns. The model identifies three key ingredients determining long-term stability: mutual attraction, emotional erosion, and individual reactions.
This study reveals that off-the-shelf large language models do not exhibit universal risk profiles and can be affected by prompt language, leading to systematic distortions. The findings highlight the need for rigorous empirical calibration before deploying these models in computational social science and choice modeling.
Researchers have discovered three well-preserved silkworm cocoons at an archaeological site in Uzbekistan that push back the earliest verified date for silkworm cultivation outside of China by nearly 2,000 years. The findings suggest that East Asian mulberry sericulture had reached southern Central Asia as early as 4,000 years ago.
The study of Alan Turing's unpublished short story 'Pryce's Buoy' reveals a more nuanced understanding of the computer scientist. The six-page fragment challenges the stereotype of Turing as socially unaware and isolated, instead portraying him as playful, funny, and emotionally expressive.
Researchers have identified transmembrane 4 L six family member 1 (TM4SF1) as a highly selective surface marker of senescent β-cells in both mice and humans. This discovery provides an important step toward developing targeted senotherapies that could preserve insulin secretion and slow the progression of type 2 diabetes.
A comprehensive, sustained approach to treating tobacco dependence in patients undergoing cancer treatment has been shown to double quit rates compared to referral to a Quitline alone. The study found that 81% of participants who received virtual sustained treatment attended counseling sessions and had higher medication use rates.
The US Naval Research Lab is developing continuous biomanufacturing technologies to produce critical materials more efficiently and sustainably. The approach uses surface-bound microbial cells to generate valuable compounds over extended periods, reducing energy requirements and equipment size.
Researchers have developed an AI-based thickness-optimized acoustic hologram (TOAH) technology that directly optimizes the thickness of a 3D-printed lens to stimulate multiple brain regions. The technology enables precise multi-site brain stimulation using only a single thin lens and ultrasound transducer.
Researchers at Penn State have created a material memory system where two types of memory coexist and compete. At lower intensities, the mixture retains both directional and amplitude memories. However, as intensity increases, one memory weakens and is eventually erased, while the other becomes dominant.
Rice University has received a nearly $20 million NSF award to lead an AI-powered materials laboratory that aims to accelerate the manufacturing of electronic and quantum materials. The project, READINESS, will integrate automated synthesis equipment, robotic systems, and digital twins to minimize trial-and-error experimentation and en...
The journal aims to bridge the gaps in real-world deployment, long-term safety, and systemic equity by establishing a comprehensive research pipeline focused on clinical efficacy, implementation, and safety. Research exploring workflow compatibility, equitable access, user engagement, and economic sustainability of DMHIs is welcome.
A study analyzing over 180 ceramic vessels from southern Brazil reveals differences in diet among Indigenous, African, and European communities. Marine resources were more prevalent among Indigenous and Afro-descendant communities, while German immigrants relied on plant-based products.
Researchers at Nagoya University discovered that complement C3 protein acts inside tumors to prevent immunosuppressive cells, improving cancer immunotherapy effectiveness. Higher levels of C3 in tumor tissue were associated with better treatment outcomes and survival rates in patients.
Researchers discover how tumors hijack the thymus to evade immune surveillance by transporting tumor antigens there. Disrupting a specific chemokine receptor may enhance anti-tumor immunity and improve cancer treatment outcomes.
Research suggests that time zone changes disrupt the synchronization between human biological clocks and gut microbiota, leading to digestive complaints, poorer sleep quality, and reduced energy levels. Gradually adjusting one's biological clock through light exposure and meal timing before departure can help reduce jet lag effects.
A global analysis has found that invasive alien species have a greater impact on biodiversity in the Global South due to weak governance and economic factors. Stronger governance is associated with lower IAS impacts, suggesting improved management can reduce invasion damage.
Twenty NII papers were accepted at ACL 2026, including two that won the Best Theme Paper and Outstanding Paper awards. These achievements lay the groundwork for developing trustworthy AI and advancing research in explainability and transparent AI.
A deep learning model integrating quantitative tongue image features with routine clinical data achieved high accuracy in diagnosing metabolic dysfunction-associated fatty liver disease. The model outperformed single-modality and serological models, providing a practical application for non-invasive assessment of the disease.
Researchers estimate that tens of thousands of languages were spoken between 1,000 and 3,000 years ago, with a peak in linguistic diversity around this time. The decline in language diversity began before modern European colonialism, suggesting a complex history of human cultural exchange.
The City University of New York has received an $18.1 million NSF award to create a cloud-programmable national laboratory that uses artificial intelligence and robotics to speed the discovery, design, and production of advanced bio-inspired materials. Researchers nationwide will have remote access to automated tools for developing sus...
Researchers propose three principles for sustainable robots: minimally invasive, universally accessible, and symbiotic. They emphasize the importance of considering robots' environmental and social impacts in design.
A study of almost 2800 Australians over four years found no evidence that personal environmental actions like recycling and using public transport hinder support for broader climate action. Everyday behaviours are expressions of existing values rather than catalysts or obstacles for political engagement.
A study found that Blanco de Piura cacao can produce an average of 1,200-1,500 kilograms of dry beans per hectare, matching those of commercial clones. Good tree management and agronomic practices are key to achieving high productivity levels.
Researchers at the University of Cologne have discovered a previously unknown mechanism that links two fundamental processes in mitochondria. The oxidative folding of proteins is closely linked to the formation of haem, which is essential for energy production and other biological processes.
Four top mathematicians, Yu Deng, John Pardon, Jacob Tsimerman and Hong Wang, receive the prestigious Fields Medal for outstanding achievements in various areas of mathematics. Their work has significant implications for computer science, geometry, algebraic geometry, and quantum physics.
A team of researchers found that asynchronous species fluctuations within herbivore communities play a central role in stabilizing trophic communities. Herbivore asynchrony acts as a biological buffer between plant and predator communities, mediating resource supply to predators.
Researchers used virtual reality to measure interpersonal distance in Italian and Japanese participants, finding that cultural background and first impressions influence personal space. The study suggests that virtual environments can be used to standardize the appearance of agents and observe social behavior with high precision.
A study proposes two detonation defense modes to defend against large-sized near-Earth asteroids. The novel flyby pre-excavation detonation mode offers stronger energy coupling and can destroy hundred-meter-scale asteroids, making it the preferred option when warning time permits.
A global review of migratory bird population status reveals that over half of the world's migratory bird species are declining globally. The study emphasizes the need for a new approach to biodiversity conservation, addressing complex threats throughout the birds' lifecycles and international flyways.
Knowledge graphs provide explicit reasoning and traceable decision support, while large language models excel in semantic understanding and contextual generalization. The study reveals the growing synergy between these two AI paradigms, promising a more robust and trustworthy autonomous driving system.
The new radiative transfer model CARE-RTM simulates sunlight propagation through the atmosphere and ocean with enhanced precision and speed. It provides a tool for extracting climate and environmental information from satellite data.
A new magnetic water treatment material has been developed that can remove both micro- and nano-plastics as well as some PFAS compounds from wastewater. The material is designed to work quickly and was shown to be effective in removing over 95% of microplastics, including particles as small as 30 nanometres.
A team of scientists has developed a method to control the motion of Leidenfrost droplets on a heated surface using femtosecond laser processing. The droplets exhibit a hybrid boiling state, combining the advantages of film and transition-boiling states, allowing for efficient heat transfer and directional propulsion.
Researchers have developed a novel method to control miniature rotations using water flow at a surface, allowing for the creation of targeted ultrafine structures such as twisted fibers for wires and sutures. This approach enables the assembly of complex structures without mechanical contact or chemical propulsion systems.
Researchers have developed a new approach to combat superbugs by partnering existing antibiotics with molecular compounds called adjuvants. Using this method, they successfully restored the activity of vancomycin against drug-resistant E. faecium, a potentially life-threatening infection.
Researchers have found a potential side effect of GLP-1 receptor agonists used to treat type 2 diabetes: an increased risk of non-scarring alopecia. The absolute risk is low, but awareness may inform treatment decisions. Rapid weight loss and hormonal changes are thought to be contributing factors.
A Tulane University team is using AI to discover new superconductors, which could improve the nation's electrical grid, medical imaging, and quantum computing. The project combines high-fidelity calculations, physics-aware AI, and experimental measurements to accelerate discovery.
Children equipped with thermal cameras are helping redesign schools to cope with hotter summers by spotting heat hotspots and developing their own cooling solutions. The 'Heat-Cool' programme has shown that children as young as nine can use thermal imaging technology to investigate how heat builds up around their schools.
Researchers found that hummingbird hawkmoths prefer one side when extending their proboscis while inspecting flowers. The strength of this preference varies among individuals, but the alignment between the eye and proboscis is maintained even when part of the eye is occluded.
Researchers found that geography and community affiliation explain more variation in gut microbiome composition than urban lifestyle. Urbanization consistently influences the gut microbiome, but the magnitude and nature of changes differ among communities, reflecting differences in local diets, environments, and cultural practices.
A recent study from Duke University and industry collaborators found that at least 1% of resumes submitted to a popular hiring platform contained hidden instructions designed to trick the AI system. The trend is accelerating quickly, with the rate increasing sevenfold between July 2024 and November 2025.