Researchers at Tohoku University's Advanced Institute for Materials Research have developed a method to summarize decades of scattered literature data into actionable information for catalyst design. By combining human intelligence, regression models, and AI agents, they can uncover new discoveries hidden in the literature data.
A new study reveals that the KDM3A/METTL16/PDK1 axis drives glycolysis and overcomes tyrosine kinase inhibitor resistance in non-small cell lung cancer. The research suggests that targeting this axis with PDK1 inhibitors could be a promising therapeutic strategy for overcoming acquired drug resistance.
The ESOT FiSensor combines electrical signals with light transmission, allowing simultaneous monitoring of vibration, pressure, temperature, and strain through a single fiber. Tests show exceptional performance with over 90% sensitivity retention after traveling 50 meters.
The SEB Conference 2026 will take place in Florence, Italy, from July 7-9, featuring over 600 talks on advances in experimental research. The event's theme is 'Reslience,' covering topics like biomechanics, wildlife conservation, and bio-inspired robotics.
Researchers developed anisotropy-tunable mesoporous polydopamine nanomotors with POM-mediated assembly, which combine intrinsic antibacterial activity, self-propulsion, and high drug-loading capacity. These nanomotors demonstrate enhanced antibacterial efficiency and biofilm eradication against drug-resistant bacterial biofilms.
The DFG is establishing 10 new Research Training Groups to support early-career researchers. Three of these groups are International Research Training Groups with partners in Australia and France. The groups aim to develop innovative materials, investigate conflict resolution strategies, and improve urban sustainability.
A new ultra-lightweight AI model, Multinex, advances low-light image enhancement by leveraging classical colour vision theory and Retinex principles. The model outperforms comparable compact systems, recovering detail and clarity from previously unusable images.
Researchers investigated the mechanism of a special glutamate receptor complex, GluK2/GluK5 kainate receptor heteromer, which consists of two GluK2 and two GluK5 subunits. Ligand binding at just the two GluK5 subunits is sufficient to cause receptor activation.
A nonvolatile phase-programmable spintronic terahertz emitter has been developed, allowing for ultrafast programming of terahertz wave phases. The device demonstrates reversible write-read-reset processes and spatial terahertz phase patterning with high signal-to-noise ratios.
A recent study found that SNAI1 overexpression drives cellular senescence, ribosome biogenesis, and DNA damage in renal tubular cells, exacerbating kidney fibrosis. The researchers identified 233 proteins with altered expression levels and demonstrated that Snail1 amplifies the senescence-associated secretory phenotype.
Researchers used X-ray fluorescence spectroscopy to analyze the paint layers of Mercker's 'Die Stätte des 9. November', revealing Nazi symbols covered up in oil paints containing titanium white. The study sheds light on the collaboration between artists and the Nazi regime during this period.
A cohort study found that smartphone acquisition at age 13 was linked to increased risk of insufficient sleep at age 14. Excessive smartphone use was also tied to higher odds of depression and obesity. Limiting screen time may protect adolescents from these outcomes.
Researchers found that Buyang Huanwu Decoction alleviates acute inflammation following spinal cord injury by regulating the complement and coagulation cascades. The treatment promotes neuroprotection and motor function recovery, suppressing microglia-mediated inflammation.
The NYU Earth Systems Institute aims to predict environmental changes and advance measures to prepare for a changing planet. The institute combines AI, engineering, and natural science expertise to improve weather and climate projections and strengthen food, water, and energy systems.
A new study has found that standard antibody-based tests can fail to detect all gluten residues in barley beer, leading to concerns about the safety of gluten-free products. Researchers developed a new mass spectrometry method to identify celiac disease-active peptides, which were found in some 'gluten-free' beers.
Scientists have isolated a key gene from maize's wild ancestor, teosinte, which enhances seed protein content. The study reveals the molecular mechanism behind the decline in maize protein content during domestication and provides a powerful genetic tool for breeding high-protein maize varieties.
Researchers at Istituto Italiano di Tecnologia developed an octopus-inspired soft robotic arm with integrated tactile sensors, enabling autonomous grasp and manipulation in aquatic environments. The system combines distributed tactile sensing and decentralized control to detect contact and adapt grip autonomously.
Researchers developed a lock-in thermography-based method to rapidly characterize structural imperfections in freestanding oxide membranes. The study found distinct thermal responses for different types of defects, including microcracks and wrinkles, enabling efficient defect screening and quality evaluation.
A study found that implementing earlier egg introduction guidelines resulted in measurable decreases in egg allergy cases. The updated guidelines, based on randomized trial evidence, may contribute to a reduction in food allergy prevalence when effectively implemented.
Postoperative delirium is a strong predictor of long-term cognitive decline in older adults, according to a new study. Researchers found that delirium was associated with faster cognitive decline than mild cognitive impairment, and rehospitalizations did not explain the effect.
A study characterizes peripheral immune alterations in systemic juvenile idiopathic arthritis, identifying a distinct CD14+CXCL10+ monocyte subpopulation associated with inflammatory network remodeling and disease activity. The monocyte subset is enriched in active sJIA states and exists in a heightened state of immune surveillance.
A new study has uncovered how antidepressants affect different groups of serotonin-producing brain cells in opposite ways. Researchers found two distinct subpopulations of neurons that respond differently to SSRIs, mirroring the clinical picture where unpleasant effects come first and relief comes later.
A digital model guides cleaner biohydrogen production by resolving the balance between microbial growth, by-product formation, and hydrogen generation. The study reveals that amino acid biosynthesis and selected gene targets can improve fermentative biohydrogen production, with potential applications in industrial biotechnology.
A recent study found that melanoma disproportionately affects Florida's senior population, with older men experiencing twice as many skin cancer-related deaths as women. The study highlights gaps in prevention and early detection, particularly among men and non-Hispanic populations.
The American Heart Association warns that extreme heat events are increasing, posing significant cardiovascular risks. The statement outlines contributing factors and recommendations to mitigate these risks, particularly for vulnerable populations such as older adults and those with low incomes.
A new paper by over 20 protein experts examines widely held propositions about dietary protein, concluding that some science is insufficient or not robust enough to support certain claims. Key findings include the importance of protein quality, individual essential amino acids, and nuance in high-protein intake during weight loss.
A major security vulnerability was discovered, allowing attackers to fake their identity in smartphone text conversations by exploiting the difference between email and text message formats. The issue was patched in Android and Apple smartphones as well as all major wireless carriers, including Verizon and T-Mobile.
The Laboratory in Northern Kenya (LiNK) improves conservation-led veterinary medicine by providing accessible diagnostic infrastructure. The lab, established through a collaborative partnership, serves the northern Kenya landscape and enhances the country's national wildlife health infrastructure.
Researchers at Chiba University successfully synthesize bisleuconothine A and bousigonine B using a new organocatalytic reaction, unlocking the efficient production of these complex alkaloids with unique medical potential. The development paves the way for new therapeutics and accelerates research into complex indole alkaloids.
Researchers developed a mathematical formula to estimate microplastic mass and size concentrations from limited data, enabling more efficient surveys. The new approach allows for the estimation of small microplastics often overlooked in field surveys, which can help track pollution sources and trends.
Researchers uncover how a previously uncharacterized transporter protein controls magnesium transport in rice, leading to improved grain development, nutritional quality, and cooked texture. The study reveals that magnesium transport is closely linked to crop productivity and sensory traits.
By inducing rhythmic on-and-off activity in small portions of the brain, researchers triggered a recalibration of neural connections that normally only occurs during sleep. This approach offset the effects of sleep deprivation and revealed features of sleep key to its restorative effect, including improved tactile memory tasks.
Researchers found that superheating in magma delays crystal formation, allowing magma to rise rapidly and potentially promoting dramatic lava fountaining behaviour. This discovery helps address a long-standing scientific debate on how magma's thermal history influences crystallisation processes before and during eruptions.
Researchers found dapagliflozin significantly reduces risk of heart failure hospitalization in individuals carrying a cardiomyopathy genetic variant. The study, published in Nature Medicine, highlights the potential for incorporating genetic screening into heart failure prevention strategies.
Researchers analyzed DNA in ancient dental calculus to understand past oral microbiomes, finding differences in composition and phylogenetic relationships across time periods. The study provides new insights into the history of relationships between humans and microorganisms.
The Cozumel dwarf fox, a critically endangered species, has been rediscovered after two decades. The fox was rescued and released into the Laguna Colombia State Reserve, highlighting the need for urgent conservation measures to preserve its habitats.
The Seoul National University research team created an ultra-low-voltage electrochemical organic light-emitting transistor that performs signal processing, memory, and light emission within a single semiconductor device. The device achieved wide, stable light emission at low voltages without high voltages or unstable n-type doping.
A study found that most persistent viral detection despite effective therapy is due to defective, non-infectious virus copies. The 5'-leader region of the virus is responsible for producing infectious particles, but defects in this area prevent the generation of functional viruses.
Researchers at Aalto University have developed metacrystal panels that can shape wireless signals without electronics or active tuning. These affordable 3D-printed devices can redirect signals around corners, into shadowed areas, or toward specific users or devices, improving wireless connections in hard-to-reach places.
New research shows that antibiotics can drive bacterial resistance even after they are broken down in wastewater treatment plants and discharged into rivers and seas. The study found that some metabolites form when antibiotics break down retain the ability to promote antibiotic resistance.
A €6 million EU Horizon project is building Europe's first platform to coordinate a response to devastating agricultural and forest pest invasions. Plant health authorities will be able to model and optimise pest control strategies across the entire agri-value chain.
A new UTEP study found that patients taking weight loss medications like Ozempic and GLP-1s have a lower risk of developing alcohol, opioid, nicotine, and cocaine use disorders. The study's findings suggest these medications may influence dopamine signaling and other neural pathways involved in cravings.
A recent study found that fewer than one in five people meet the recommended flavanol intake to reduce heart disease risk. The study tracked over 30,000 participants and suggests specific food choices, like blueberries and green tea, can significantly impact flavanol consumption.
Research found that children who play outdoors more frequently during the preschool years are less likely to develop emotional and behavioral difficulties later in childhood. This study suggests that providing young children with more opportunities to play outside could support better mental health.
Researchers identified specific gene mutations and characteristics associated with early-onset breast cancer in young Black women. The study highlights the importance of genetic testing for this population, which faces lower screening rates than other groups.
A new compound, compound 10, has shown promising effects in slowing the development of Alzheimer's disease by inhibiting GRK2 aggregation. This leads to improved mitochondrial function and reduced amyloid beta deposition, potentially breaking a vicious circle that contributes to dementia progression.
Researchers at the University of Gothenburg found that horses in a children's zoo showed no significant increase in heart rate when petted by children, despite other sounds like barking dogs having no effect. However, they did exhibit increased stress when exposed to noise from an excavator.
Large-scale simulations show that chemical impurities trigger graphitic interface formation in amorphous carbon, promoting low-friction surfaces. Hydrogen and oxygen-based impurities help stabilize tiny voids within the carbon network.
Researchers found that rewetted peatland solar parks in Northern Germany support threatened bird species and exhibit an unusual mix of species, providing a unique habitat for biodiversity. The study suggests that this novel land use can be a valuable tool for reducing greenhouse gas emissions and restoring peatland ecosystems.
Researchers at the University of Waterloo developed a flexible polymer shield that provides radiation protection without the health and ergonomic risks associated with lead. The new material weighs almost 90% less than traditional aprons while maintaining excellent X-ray shielding.
Direct-type perovskite detectors have surpassed commercial alternatives in sensitivity and detection limits, but scaling up for large-area flat-panel X-ray imaging remains a challenge. The review discusses scalable material fabrication, backplane integration, and imaging performance optimization to enable widespread adoption of high-qu...
A KAIST research team has developed a technology that controls the chemical environment around catalysts at the nanometer scale by designing DNA sequences. This allows for improved hydrogen production efficiency and increased yield of desired chemical products. The DNA layer acts like a traffic control center, guiding the movement of i...
A novel silylium Lewis acid organocatalysis technology was developed, allowing for the direct installation of sulfonamide groups into ketone compounds. The catalyst enables precise control over reaction rate and substrate activation, achieving high yields in a sustainable process.
Researchers found that zirconia implants trigger an immune-inflammatory niche marked by macrophage involvement and COL6A2/CD44 signaling. In contrast, titanium implants support a regenerative microenvironment with collagenase-1/stromal-derived cell differentiation 1 (SDC1) signaling.
Researchers found that ancient hominins selected specific basalt sources for tool production, demonstrating advanced planning abilities and long-term technological traditions. This discovery highlights the ability of Acheulian hominins to plan, select, and exploit geological resources within a changing landscape.
A three-year study reveals coral hormone cycles similar to humans', helping detect reproductive stress and informing reef conservation. Hormone levels were found to be influenced by sunlight, not heat, and distributed evenly throughout colonies.
Researchers discovered that Cyanobacteria survive extreme heat through dark respiration compensating for impaired photosynthetic electron transport. A heat-tolerant strain increased respiratory activity to support energy needs when photosynthesis is weakened.
A CDC study found that most NDM-CRE cases were caused by a few high-risk strains, primarily from Klebsiella pneumoniae and Escherichia coli. The discovery of new high-risk clones highlights the importance of genomic surveillance to catch emerging threats early.
Kirigami researchers create twisty structures for flexible robotic components and soft actuators, exploiting geometrical design to enable rotation under stretching. The unique mechanical properties of these kirigami materials offer new potential applications in robotics and engineering.
A study of over 229,000 obese adults without diabetes found that weight loss drugs, such as semaglutide and tirzepatide, were associated with a 41% decrease in the overall risk of developing obesity-related cancers. GLP-1 RAs also showed larger reductions in certain subgroups, including men and gynaecologic cancers.