AI is increasingly being used in stroke rehabilitation to predict recovery trajectories and monitor motor function, providing adaptive and continuous care. The review highlights the need for standardized outcome measures and data pipelines to determine the clinical impact of AI-based monitoring.
Researchers have developed a triple-layered artificial nerve conduit embedded with living cells that steers nerve regrowth across deep gaps, achieving functional recovery in rats that rivals a natural graft. The bioprinted nerve 'railway tracks' guide regenerating tissue, promoting axon-guidance genes and restoring electrical impulses.
A meter-scale flapping-wing robot demonstrates the benefits of low-angle takeoff, increasing flight distance by 49% and horizontal distance by 123%. The robot's ability to control pitch attitude through the flapping-pitch effect enables early acceleration and speed advantage.
Researchers identified cell-type-specific circadian gene programs and phase-specific pathway activities in liver and skeletal muscle. The study provides evidence for a cell-type-resolved circadian landscape and candidate transcription factors, suggesting potential circadian therapeutic windows.
A new study warns of the increasing impact of climate change, urban living, and digital misinformation on sleep health across Europe. The researchers call for coordinated action to protect sleep health, improve sleep health literacy, and tackle structural inequalities.
The strain accelerates wheat straw decomposition, reduces fungal proliferation, and decreases aflatoxin content, promoting peanut seedling growth and supporting sustainable agriculture. SQ1 functions as a dual-purpose biocatalyst, breaking down cellulose and inhibiting fungal growth.
A new study has reconstructed the genetic history of the Iberian Peninsula between the 1st and 8th centuries CE, revealing that Roman Hispania's genetic legacy survived the arrivals of the Suebi, Alans and Visigoths. The study found that Roman rule created an extraordinarily diverse society due to population movements across the Medite...
Jennifer Lewis, a Harvard professor, has been elected to the National Academy of Medicine for her pioneering work in 3D bioprinting and vascularized organoids. Her research focuses on developing functional materials for applications in printed electronics, artificial muscles, and human tissue engineering.
Researchers found women can expect to spend more years over their lifetimes caring for aging family members or friends, with a 3-year gap from men. This disparity extends to caring for parents, grandparents, and extended family and friends, highlighting the need for increased support and resources for caregivers.
A McGill University study found that Montrealers reduced their outdoor activities by only 5.8% when wildfire smoke warnings were issued, switching to more enclosed modes like bikeshare and public transit. The researchers suggest pairing advisories with practical incentives to encourage compliance.
Maladaptive brain-state locking (MBSL) is a lifespan hypothesis suggesting that distinct disorders converge on impaired state-transition or recovery dynamics. Candidate features include abnormal persistence, impaired transition, and delayed recovery, with lifespan timing and regional context modifying phenotypic expression.
A massive, 1-mile-thick ice shelf in Baffin Bay helped lock in three of the largest ice sheets in northern Canada and Greenland, contributing to hundreds of feet of sea-level rise. The discovery provides new insights into the future of Antarctica's massive ice sheets and the potential for sea-level rise.
Researchers discovered a signalling system regulated by metabolites that extends lifespan and delays age-related decline in animals. Muscle tissue produces the metabolite dihydrobiopterin (BH2), which is transported to other tissues to maintain protein homeostasis and tissue health.
Physicists at Northwestern University trap and cool a single positron, creating a controlled quantum state that allows for precise measurement of its magnetic properties. This breakthrough could reveal a crack in the Standard Model, offering new insights into the universe's matter-antimatter imbalance.
Researchers at Baylor College of Medicine discovered distinct astrocyte subtypes, CD51+ and CD51-, which have specialized jobs in forming synapses, shaping memory circuits and aiding recovery after stroke. These findings challenge the long-held assumption that astrocytes are uniform support cells.
Researchers discovered a new role for Wee1 in healthy cells, which could explain toxic side effects in cancer patients. Wee1 helps switch off a protein degradation complex, delaying cell division. This finding may lead to more targeted therapies and identify patients most likely to benefit from treatment.
A mouse study of Angelman syndrome identifies a potential opportunity to restore healthy neurodevelopment by targeting the buildup of a normally harmless enzyme, asparagine synthetase. The findings suggest that the enzyme's accumulation triggers a stress response that impairs brain growth.
A recent study found that overdose-reversing drug naloxone use did not increase relative to the number of overdoses in the US since 2023. Instead, nonfatal drug overdoses fell by 20.9% and opioid-related overdoses dropped by 32.7%.
Researchers have discovered a new way in which the Andes virus captures its receptor on human cells, a finding that could lead to effective therapies. The study reveals details on the molecular specifics of the interaction, including a deep groove or pocket that limits antibody access.
Zeolites can catalyze new olefin carbonylation reactions, enabling the selective production of chemical building blocks. The team discovered a key design principle: the location and size of zeolite pores determine which olefin molecules can be selectively carbonylated.
A Lehigh-led team is developing an AI platform called UniBrain to simplify brain imaging analysis, reducing the time and expertise required. The platform aims to unify image preprocessing and downstream brain network analysis, integrating information from multiple imaging modalities.
A study from Northwestern University found that a personalized fitness program for liver transplant candidates can significantly improve frailty and reduce mortality risk by 50%. The program, called prehabilitation, was linked to a lower risk of dying while awaiting a transplant.
Researchers at FAU's Harbor Branch Oceanographic Institute will investigate environmental and biological mechanisms driving harmful algal blooms in subtropical estuaries. The project aims to refine predictive models to mitigate blooms in other estuaries, with potential economic benefits of $28.3 billion.
Researchers at Chalmers University of Technology developed a new optimisation method for near-optimal large-scale fleet control, accounting for uncertainties in real-world transport systems. The method combines machine learning techniques with advanced optimisation models to predict travel demand and charger availability, improving fle...
Canadian Science Publishing launches a new collection of French-language scientific articles, strengthening the creation, dissemination, and mobilization of scientific knowledge in French. The inaugural collection features 14 articles exploring topics of significant importance, including forestry, Indigenous knowledge, and biodiversity.
New research models energy demand extremes in the US, finding that technology diffusion may have a larger impact than climate change on peak demands in certain regions. The study considers four climate change scenarios and 18 technology diffusion pathways in 183 counties across the US, projecting changes in extreme peak demands.
The BabyMERIT trial will evaluate trametinib in infants with Noonan syndrome and related conditions who develop severe hypertrophic cardiomyopathy, a potentially life-threatening condition. The study aims to improve outcomes for these young patients by targeting a molecular pathway known to drive these disorders.
A new open-source software package called PFclassify enables researchers to classify and quantify unprocessed and processed meats into separate subtypes, providing more accurate nutrition data. This gives scientists a standardized workflow to examine meat subtype-specific dietary intake, supporting more transparent and higher quality d...
Researchers have found that supernovae may not have played a central role in reionizing the early universe, contrary to long-held theory. Instead, young stars may have helped radiation escape, with winds from supernovae creating a barrier to ionizing radiation.
The grant will support Dr. Flanagan-Steet's research into understanding how metabolism and glycosylation work together during normal development and disease onset. The study aims to identify common biological pathways that contribute to rare diseases, with the ultimate goal of developing new treatments.
A consortium of researchers and clinicians aims to develop living cardiac tissues and components for infants and young children with congenital heart disease. The THUMPIN' initiative, supported by a $29.6 million contract, will create living heart tissue that can grow and adapt throughout childhood.
A new review shows how climate change alters microclimates, which can differ substantially from regional climate averages. Vegetation and atmospheric changes, such as cloud cover, influence local climate conditions, affecting biodiversity responses to climate change.
A new study from Okinawa Institute of Science and Technology uses computational models to shed light on the evolutionary origins of potassium conduits, identifying spike timing as a probable evolutionary pressure. The research suggests that higher unitary conductance channels, found in mammals and birds, were essential for achieving pr...
Researchers used Cell Painting to study 52 cancer drugs in 3D minispheres, revealing differences in how they affect cells. The study found that two drugs, 5-fluorouracil and olaparib, behaved differently when looking at individual cells, with 5-fluorouracil causing less DNA damage but stopping cells from dividing more effectively.
The ECOG-ACRIN Cancer Research Group will conduct a phase 2/3 clinical trial to evaluate ivonescimab combined with chemotherapy for first-line treatment of advanced biliary tract cancer. The trial aims to test the efficacy of ivonescimab beyond standard chemotherapy and immunotherapy.
Researchers found that higher postpartum depression scores were associated with greater mother–infant bonding difficulties, which can affect maternal well-being and child development. Repeated assessments identified varied symptom patterns, including mothers whose bonding difficulties increased during the first three months.
EPND+ builds on five years of public-private collaboration, supporting existing and future research collaborations in neurodegeneration and beyond. The new organization will operate the EPND Hub, providing a unified gateway to valuable research resources, data, and biosamples.
A recent study by Flinders University found that women with postpartum psychosis often contact healthcare services seven times before receiving a diagnosis. The research highlights the need for greater awareness of the condition and timely assessment to improve outcomes for mothers and their families.
Research found single mothers' children experienced decline in math, reading, and early motor development after EITC expansion, attributed to reduced time with parents. Increased employment among single mothers may outweigh income benefits for children's development, emphasizing need for affordable childcare.
Researchers have identified a gene that regulates tea plants' flavor and cold tolerance, providing insights into how to expand high-quality tea production. The study's findings suggest that targeting this gene could improve both flavor quality and stress resilience in tea plants.
Researchers found sustained increases in hospitalizations and deaths among Medicare beneficiaries aged ≥65 years in North Carolina after Hurricane Matthew. The study also showed a stronger association between hurricane exposure and hospitalizations and deaths, with Black individuals experiencing worse outcomes.
A study found that regular tea consumption was linked with an 11% lower risk of cardiovascular disease, with the lowest risk estimated at approximately 6–8 cups per day among weekly drinkers. Black tea showed more consistent inverse associations with vascular disease than green tea.
A study of 15 Australian women with postpartum psychosis found that they experienced delayed recognition, inadequate assessment, and dismissal of their concerns. The findings emphasize the need for professionals to listen to women's accounts and respond appropriately to improve outcomes.
New research suggests that heat-based recovery strategies may influence some biological processes involved in recovery following muscle-damaging exercise, but do not translate to significant improvements in muscle strength or soreness over a 72-hour period
Researchers used palaeoproteomics to analyze ancient proteins in sediments from a 60,000-year-old archeological site in South Africa, revealing the presence of collagen from the common eland. The findings provide new insights into the complex technical and symbolic behaviors of early Homo sapiens.
Researchers developed a heat-informed framework to assess available playing time and evaluate tournament schedules under hot conditions. The study found that adjusting playing hours had a stronger effect on the availability of low-risk hours than changing tournament dates.
Researchers found that IT vulnerabilities in automotive software have shifted to apps and cloud services, posing risks to driver data and car control. Experts advise car manufacturers to secure systems and encourage owners to update software and use strong passwords
Researchers developed a high-entropy perovskite to protect iridium nanoparticles, improving the stability of catalysts used in water electrolysis. The new design allowed the catalyst to last over 3,800 hours with minimal loss in performance.
Scientists have discovered ancient fish bones in deep-sea sediments, providing evidence of past vertebrate life in the central Arctic Ocean. The findings reveal that two Arctic-endemic fish species, ice cod and polar cod, survived the last ice age, with ice cod thriving in polynyas and polar cod disappearing from the North Pole area.
Researchers at Tohoku University developed a new method to predict the mechanical properties of iron ore pellets under extreme heat, combining high-energy X-ray CT with computer simulations. The findings could help improve the efficiency and stability of blast furnaces, enabling the steel industry to move toward lower-carbon production.
The Whitley Award-winning book, Australian Moths: A Natural History, brings together three decades of research on moth evolution, ecology, and conservation. The book, edited by Prof. Roger Kitching, is a comprehensive synthesis of the latest understanding of moths in Australia.
A research team at POSTECH developed an AI technology that analyzes genetic information from cancer patients to predict their response to immunotherapy. The study, published in npj Digital Medicine, outperformed biomarkers in predicting treatment response across four cancer types and six patient cohorts.
A research team has identified the conditions that allow rapidly feeding supermassive black holes to launch powerful relativistic jets. The team observed 3C 120, an active galaxy with a supermassive black hole rapidly accreting matter while launching a powerful jet.
Researchers identify five types of war brownfields with distinct recovery paths, including remnant military fortifications and radioactively contaminated sites. These landscapes require tailored approaches, taking into account security risk, environmental consequences, and heritage value.
A new fibre blend, ur gut®, has been found to improve gut health in people with IBS without worsening symptoms, according to an ECU study. The fibre blend, which combines resistant starch and psyllium husk, positively reshaped the gut microbiome in participants.
A revised water footprint estimates water consumption in agriculture and forestry, distinguishing between blue water and green water usage. The study found that human water appropriation in south-central Chile was 2.7 times lower than conventional estimates, with forestry plantations being a major source of rainwater appropriation.
China's 70-year soil conservation journey shows that environmental recovery takes time, requiring sustained work of 10 to 20 years. The country's experience highlights the importance of integrating engineering, ecological restoration, law, and local livelihoods to address different forms of erosion.
A team of scientists discovered that radiation defects can form local 'core-shell' structures in silicon carbide, affecting its properties. The defect area becomes unstable, surrounded by a region with stronger bonding, modifying the electronic environment of nearby atoms.
Researchers from Hefei Institutes of Physical Science, Chinese Academy of Sciences, have discovered that high pressure can transform single-layer nickelate La2NiO4 into a metal without destroying its magnetic order. Strontium doping also alters the material's magnetic moments, leading to ferromagnetism at high doping levels.
Researchers found sex-specific differences in fetal brain gene expression linked to advanced paternal age, shedding light on autism's biological mechanisms. Female embryos conceived by aged fathers showed distinct gene expression profiles and increased gene expression levels.