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GLP-1RA and SGLT2i medications for type 2 diabetes and Alzheimer disease and related dementias

04.07.25 | JAMA Network

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About The Study: In people with type 2 diabetes, both glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter-2 inhibitors (SGLT2is) were statistically significantly associated with decreased risk of Alzheimer disease and related dementias compared with other glucose-lowering drugs, and no difference was observed between both drugs.

Corresponding Author: To contact the corresponding author, Jingchuan Guo, MD, PhD, email guoj1@ufl.edu .

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamaneurol.2025.0353)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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JAMA Neurology

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How to Cite This Article

APA:
JAMA Network. (2025, April 7). GLP-1RA and SGLT2i medications for type 2 diabetes and Alzheimer disease and related dementias. Brightsurf News. https://www.brightsurf.com/news/LN2EO291/glp-1ra-and-sglt2i-medications-for-type-2-diabetes-and-alzheimer-disease-and-related-dementias.html
MLA:
"GLP-1RA and SGLT2i medications for type 2 diabetes and Alzheimer disease and related dementias." Brightsurf News, Apr. 7 2025, https://www.brightsurf.com/news/LN2EO291/glp-1ra-and-sglt2i-medications-for-type-2-diabetes-and-alzheimer-disease-and-related-dementias.html.