A study published in Neurology found that zonisamide significantly improved tremors and dyskinesias in Parkinson disease patients. The medication was effective at 50mg/day, with a nearly 40% improvement in symptoms.
A study published in Neurology found that a gene variation linked to longevity also protects brain function in individuals over 90. Researchers analyzed 158 centenarians and found they had twice the likelihood of good brain function compared to those without the variant.
A study published in Neurology found that methamphetamine use is associated with an increased risk of major neck artery tears and stroke. The research reviewed two cases of women who experienced sudden speech difficulty and weakness after using the drug, resulting in severe strokes from carotid artery dissection.
A study published in Neurology found that people with Parkinson disease were more likely to make safety mistakes during a driving test than those without neurological disorders. The study involved an on-road driving test of participants with mild to moderate Parkinson disease and those of similar age without neurological disorders.
A study published in Neurology found that pregabalin significantly reduced severe pain and anxiety problems in patients with moderate to severe nerve pain after spinal cord injury. The medication was effective in relieving pain, improving sleep, and overall well-being.
The new guideline aims to improve diagnosis and treatment of status epilepticus in children with epilepsy. It recommends considering anti-epileptic drug levels and performing an EEG to determine the cause of continuous seizures.
A recent study published in Neurology found that nearly 40% of children and teenagers with migraines no longer experience headaches 10 years later. Kids with a family history of migraines are more likely to still have migraines by adulthood.
A study published by the American Academy of Neurology found that childhood IQ and physical fitness are indicators of cognitive ability in old age. The research examined 460 participants who underwent cognitive tests at ages 11 and 79, revealing that physical fitness contributes more to cognitive function than childhood IQ.
A study analyzing 45 years of stroke research found that 75% of unpublished studies had negative or harmful results, while only 6% of published studies shared this outcome. The findings support the need for registering all clinical studies before they begin to prevent publication bias.
A study published by the American Academy of Neurology found that long-term lead exposure is linked to cognitive decline in older adults. The researchers tested 985 participants and found higher tibia lead levels were consistently associated with worse cognitive performance on tests, equivalent to two to six years of aging.
A study of 120 older adults found significant memory problem complainants had reduced gray matter density in the brain, even without a diagnosis of Alzheimer's disease or mild cognitive impairment. This suggests that memory complaints may indicate an early 'pre-MCI' stage of dementia.
A study published in Neurology found that children with autism have altered brain anatomy, including differences in gray matter and brain size compared to children with typical development. The researchers used MRI scans to measure the transverse relaxation of cortical gray and white matter in the brains of autistic children.
A study projects ischemic stroke costs to reach $1.52 trillion from 2005-2050, with African Americans and Hispanics facing higher costs. The American Academy of Neurology urges Congress to increase NIH funding to halt the impending epidemic and save lives.
A recent study published in Neurology found that the epilepsy drug valproate poses a significantly higher risk of fetal death and birth defects than other commonly used epilepsy drugs. The study, which examined 333 pairs of mother and child, showed that over 20% of pregnancies exposed to valproate resulted in death or birth defects.
A new guideline developed by the American Academy of Neurology can predict the outcome for patients in a coma after CPR with great accuracy. The tests used to make these predictions include absent pupillary reflexes and corneal reflexes, as well as absent motor responses three days after cardiac arrest.
Researchers have mapped a link between the size of the hippocampus and progression to Alzheimer's dementia. The technique allows for subtle anatomical differences to be detected, which holds great promise for predicting cognitive decline and improving patient counseling.
Cuba Gooding Jr. receives the award for his work raising awareness about multiple sclerosis, a condition affecting millions worldwide. The American Academy of Neurology recognizes his efforts to educate and support those living with MS.
A study published in Neurology found that over 70% of people with Chiari Malformations experience sleep apnea and daytime sleepiness. Surgery to relieve compression on the brain stem improved symptoms, reducing central sleep apnea occurrences by 90% and micro-arousals by 30%.
A recent study published in Neurology found that epilepsy surgery significantly improves mental health outcomes for patients. After the surgery, 9% of participants met the criteria for depression, compared to 22% before surgery. The study suggests removing dysfunctional brain areas may be critical to improving mental well-being.
A study published in Neurology found that depression and anxiety disorders decreased by over 50% two years after epilepsy surgery. Participants who underwent successful surgery without seizures were more likely to be free from depression and anxiety.
A prestigious team of international editors led by Professor Donnan is launching the International Journal of Stroke, focusing on clinical aspects of stroke and providing regional news, world press reports, and topical reviews. The journal aims to reduce the burden of stroke worldwide through research and debate.
The American Academy of Neurology has supported a bill that would expand funding scope for National Institutes of Health support of embryonic stem-cell research. This move is expected to significantly advance the field while ensuring strong ethical safeguards.
The American Academy of Neurology has released new guidelines for treating essential tremor, recommending medications such as propranolol and primidone to reduce limb tremors. Surgery is also an option when drug therapy is ineffective, with deep brain stimulation found to be more effective than thalamotomy in reducing tremors
A new study found that erythropoietin reduced inflammation and cell death, improving functional recovery after hemorrhagic stroke in rats. The treatment also showed decreases in brain water content and increases in behavioral recovery.
The American Academy of Neurology presented Leeza Gibbons with the Public Leadership in Neurology Award for her advocacy work on Alzheimer's disease. Her foundation, Leeza's Place, provides community-based locations offering comfort, education, and care to those affected by memory disorders.
A study of 68 patients with probable Alzheimer's disease found that higher levels of spirituality and religiosity may slow cognitive decline. Spirituality and private religious practices accounted for 20% of the total variance in cognitive decline.
Dr. Sahin will investigate the role of SMN protein in motor axon growth and identify potential therapeutic targets for SMA. The award provides support for his research and that of his mentor, Dr. Greenberg.
Dr. Morris and Dr. Petersen have developed methods to detect preclinical Alzheimer's disease, a precursor to the onset of symptoms. Their research has the potential to identify a pre-clinical stage of AD that can be targeted for disease-modifying therapies.
The American Academy of Neurology has established a definition for the persistent vegetative state, a condition characterized by minimal responsiveness and limited brain activity. This definition provides clarity and consistency in the diagnosis and care of patients in this state.
The American Academy of Neurology has developed a standardized case definition for polyneuropathy, which improves the accuracy of diagnosis and treatment. The new guideline uses a combination of neuropathic symptoms, signs, and abnormal electrodiagnostic studies to diagnose distal symmetrical polyneuropathy.
The American Academy of Neurology recognizes Dr. Callaghan's efforts to advocate for tort reform in Washington state, while Dr. Wasay leads programs to improve public health in Pakistan. The Palatucci Advocacy Leadership Forum empowers neurologists to advocate for patient care improvements.
Researchers found that switching from brand phenytoin to generic phenytoin can lead to increased seizures in epilepsy patients. Additionally, a study on concussion history and symptom reporting found that athletes with previous concussions reported fewer symptoms immediately after the injury but more symptoms one week later. The Americ...
The American Academy of Neurology discusses the growing field of cosmetic neurology, which aims to enhance normal abilities through medical therapies. Experts weigh the benefits and risks of neurological enhancements, including concerns about safety, equality of access, and coercion to compete at a high level.
Feldman et al report that donepezil treatment for six days is associated with a total societal cost saving of $224 per patient. The American Brain Coalition (ABC) was established to advocate for increased support for biomedical research.
A study found that adding aspirin to clopidogrel therapy increased the risk of intracranial and gastrointestinal bleeding in patients with a history of ischemic stroke or transient ischemic attack. Despite this, combination therapy did not significantly reduce the primary outcome measure at 18 months.
Benign paroxysmal positional vertigo (BPPV) is an inner ear problem causing spinning or whirling sensations when moving the head. A study found that performing modified Epley's and Semont maneuvers at home can lead to significant symptom relief for 95% of participants.
The American Academy of Neurology is expanding its clinical research trial recruitment efforts to improve patient care through education and research. The association has over 80% of clinical trials experiencing recruitment issues, which can delay or even prevent completion.
Researchers found that seizure-alerting dogs exhibited distinctive behaviors to anticipate seizures, with licking and protective actions being common. The study also highlights the importance of education and research in improving patient care through organizations like the American Academy of Neurology.
A randomized controlled trial found that yoga is as effective as aerobic exercise in improving measures of fatigue in multiple sclerosis patients. The study also showed improvements in physical health and quality of life among participants.
The American Academy of Neurology has developed a guideline evaluating the use of transcranial doppler ultrasound (TCD) in patients with known or suspected cerebral vascular disease. TCD provides valuable information in screening children with sickle cell disease for stroke risk and detecting vasospasms after subarachnoid hemorrhage.
A recent study by American Academy of Neurology found that patients taking pergolide for Parkinson's disease have a higher risk of developing valvular heart disease. Eighty-nine percent of pergolide-treated patients showed some degree of valvular insufficiency, with increased risks in the mitral and aortic valves.
The American Academy of Neurology and American Epilepsy Society have developed guidelines for treating newly diagnosed and difficult-to-manage epilepsy. The guidelines evaluate the safety, efficacy, and mode of use of eight new anti-epileptic drugs, offering a rigorous analysis that clinicians can use to make treatment decisions.
Two American journalists, Fauber and Singer, are selected for American Academy of Neurology Journalism Fellowships to attend the 56th Annual Meeting in San Francisco. They will learn about latest advances in neurology research and treatment, and make contacts with experts in the field.
The Canavan Disease Clinical Research Training Fellowship supports research into the cause, treatment, and potential cure of this fatal genetic disorder. McPhee plans to examine oligodendrocytes, cells responsible for white matter in the brain, to improve understanding of Canavan disease mechanisms.
Recent studies demonstrate the accuracy of epilepsy diagnosis by doctors (96%), shedding light on dementia risk factors among adults with Down syndrome. Additionally, gabapentin shows significant effectiveness in treating chronic daily headaches, according to a study by The Australian Gabapentin Chronic Daily Headache Group.
A recent Neurology journal study has identified levodopa addiction in non-parkinsonian patients, suggesting the potential for addiction to this common Parkinson's disease treatment. Additionally, researchers have discovered RNA gene slicing mutations in McArdle patients, revealing new insights into neuromuscular diseases.
A team of scientists has made a groundbreaking discovery by visualizing damaged nerve connections in living mice and tracking them over time. This breakthrough could lead to a better understanding of the underlying processes involved in Alzheimer's disease and potentially unlock new treatments.
A study of 803 women found that transition through menopause is not accompanied by a decline in working memory and perceptual speed. This research challenges previous assumptions about the effects of menopause on cognitive function, offering new insights for improving memory and addressing related health concerns.
A recent study suggests that reducing the seizure-free interval from 12 to three months does not significantly increase total crashes. The researchers found that seizures-related crashes increased by 11, while deaths due to seizure-related crashes decreased.
Researchers discuss new findings on HIV-associated dementia and its potential association with the presence of MDM. Additionally, studies suggest that treating post-Lyme disease with antibiotics does not provide benefits, while a possible link is found between insulin and Alzheimer's disease risk factors.
A study found that epilepsy surgery programs in developing countries can produce results comparable to those from developed countries using a carefully selected actuarial approach and the Seizure Scoring System. Researchers audited their program and identified factors most predictive of successful outcomes, yielding a nearly 60% succes...
A study published by the American Academy of Neurology found that deep brain stimulation significantly improved dystonia symptoms in seven patients, with three experiencing near-complete resolution. The treatment showed promise as a safe and effective therapy for previously untreatable diseases.
A study found that viral encephalitis can lead to severe movement disorders such as tremor, myoclonus, chorea, and ballismus. These disorders required heavy sedation or pharmacologic paralysis and resulted in significantly longer hospital stays compared to non-affected patients.
The AAN Annual Meeting explores the historical use of biological toxins in warfare and global terrorism, with a focus on developing bioterrorism response plans for local hospitals and clinics. Participants will learn emergency medical management and current research on neuroprotective agents against chemical warfare.
Researchers have found that simvastatin, a cholesterol-lowering medication, reduces the number and volume of active MS lesions. The study suggests statins may have therapeutic value in treating multiple sclerosis, but further studies are needed to confirm its effectiveness.
The American Academy of Neurology has launched a new online section providing patients and caregivers with practical health care information on various neurological conditions. The Patient Page section aims to give the public access to accurate and reliable information through articles written by practicing neurologists.
A recent UK study published in Neurology found no association between Gulf War exposure and specific impairments of peripheral nerves, neuromuscular junction, or skeletal muscles. The study used robust neurophysiologic tests and included representative comparison groups to rule out objective dysfunction.
The Lancet Neurology recently published a series of articles discussing the latest evidence on Alzheimer's disease, including preventative anti-inflammatory clinical trials and the role of secretases in producing amyloid-beta peptide. Researchers argue that these approaches hold promise for preventing or slowing the onset of the disease.
A global consensus on histopathological diagnostic criteria for Parkinson's disease is within reach thanks to an interactive website. NMDA receptor antagonists failed to show efficacy in clinical trials of stroke and traumatic brain injury, but lessons learned will guide new developments.
The Lancet neurology reviews research on migraine genetics, highlighting the challenges of identifying genes involved in the disorder. The article also examines the implications of private diagnostic testing without physician support, sparking debate about its role in advancing treatment options for neurological diseases.