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American Chemical Society


Solving a hairy forensic problem

Researchers developed a new method to distinguish between drug ingestion and external contamination of hair by analyzing single hairs from volunteers. The team found that splitting the hair lengthwise increased sensitivity for zolpidem detection, allowing them to separate ingestion from contamination.

SourceAmerican Chemical Society·JournalAnalytical Chemistry·DateMar 27, 2019

Sniffing out Parkinson's disease

A team of researchers discovered the chemicals responsible for the distinctive smell of Parkinson's disease using a 'super smeller'. The finding could lead to an early diagnosis and monitoring of the condition. Hippuric acid, eicosane, and octadecanal were identified as biomarkers in sebum samples from patients with Parkinson's.

SourceAmerican Chemical Society·JournalACS Central Science·DateMar 20, 2019

Powering devices -- with a desk lamp?

Researchers have developed special light harvesters that can convert ambient indoor lighting into usable energy, potentially powering wireless devices in homes and offices. The technology uses organic photovoltaics to optimize the use of artificial room lighting, which is abundant but often underutilized.

SourceAmerican Chemical Society·JournalACS Applied Materials & Interfaces·DateMar 13, 2019

Determining what binds to mucus

Researchers have developed a new technique to measure the binding of thousands of small molecules to mucus components, revealing a previously unknown pattern associated with mucin binding. This breakthrough could lead to better treatments for diseases characterized by excessive mucus production.

SourceAmerican Chemical Society·JournalBiomacromolecules·DateMar 13, 2019

Fingerprints, revisited

Researchers are developing methods to extract DNA and analyze chemicals from fingerprints, improving identification rates. These techniques involve analyzing molecules like DNA, amino acids, or explosives left behind in fingerprints.

SourceAmerican Chemical Society·JournalChemical & Engineering News·DateMar 13, 2019

Breast milk as drug-delivery device

Scientists are working on modifying human breast milk cells to produce specific proteins, such as vaccines, for premature babies. These engineered cells could potentially address birth defects, provide necessary proteins, or even treat certain diseases.

SourceAmerican Chemical Society·JournalChemical & Engineering News·DateMar 6, 2019

Capturing carbon from the air

Negative-emission technologies (NETs) that capture carbon dioxide from the air could address about 30% of needed reductions in carbon-dioxide emissions. Scientists estimate that NETs face challenges on cost-effectiveness and disposal methods.

SourceAmerican Chemical Society·JournalChemical & Engineering News·DateFeb 27, 2019

Now you see heat, now you don't

Researchers have fabricated a film using DuPont Kevlar fibers and polyethylene glycol that absorbs heat and releases it slowly, making objects invisible to thermal cameras. The composite film performs comparably to other stealth films but is simpler and cheaper to make.

SourceAmerican Chemical Society·JournalACS Nano·DateFeb 27, 2019

Detecting cyanide exposure

Researchers have identified a new biomarker, ATOEA, that accurately detects cyanide exposure and persists in the body longer than the toxic compound. This breakthrough enables faster diagnosis and treatment of cyanide poisoning.

SourceAmerican Chemical Society·JournalChemical Research in Toxicology·DateFeb 27, 2019

Sensitive sensor detects Down syndrome DNA

A new biosensor has been developed to detect fetal Down syndrome DNA in pregnant women's blood, offering a fast, sensitive, and cost-effective alternative to traditional tests. The sensor can detect DNA concentrations as low as 0.1 fM/L, making it more sensitive than other reported field-effect transistor DNA sensors.

SourceAmerican Chemical Society·JournalNano Letters·DateFeb 13, 2019

Do microplastics harm humans?

Researchers are unsure if microplastics cause harm to people as they accumulate in the body and organs, with varying effects depending on composition and additives. Microplastics have been identified in human feces, raising concerns about potential health risks.

SourceAmerican Chemical Society·JournalChemical & Engineering News·DateFeb 6, 2019

Micromotors deliver oral vaccines

Researchers create micromotors coated with red blood cell membranes and titanium dioxide that target the mucus layer of the intestine, stimulating a broader immune response. The oral vaccines successfully delivered in mice, producing ten times more IgA antibodies against Staphylococcal α-toxin than static particles.

SourceAmerican Chemical Society·JournalNano Letters·DateFeb 6, 2019

'Unclonable' tag combats counterfeiters

Scientists have created an 'unclonable' tag that can never be replicated, using physical unclonable functions (PUFs) with microparticles forming random patterns. The system correctly identified 76% of the tags, with estimated 2.5 x 10^120 unique codes.

SourceAmerican Chemical Society·JournalACS Applied Materials & Interfaces·DateFeb 6, 2019

Chemists warm up to preprint servers

Two chemistry preprint servers, ChemRxiv and ChemRN, have gained traction since their launch in 2017, allowing chemists to share discoveries freely before peer review. The sites provide a platform for quick sharing of results, feedback from peers, and increased access to research, especially for scientists in developing countries.

SourceAmerican Chemical Society·JournalChemical & Engineering News·DateJan 23, 2019

Coming soon: A blood test for Alzheimer's disease?

Researchers have made significant progress towards developing a blood test for Alzheimer's disease, with sensitive assays able to detect smaller amounts of peptides that form when amyloid breaks down. A reliable blood test could aid in diagnosis and help identify participants for clinical trials, potentially leading to better treatments.

SourceAmerican Chemical Society·JournalChemical & Engineering News·DateJan 17, 2019

Blister fluid could help diagnose burn severity

Researchers analyzed 56 samples of blister fluid from burns of different depths and healing times to develop a new classification system. They found that specific protein patterns in blister fluid could predict burn depth and time to re-epithelialization, leading to more accurate diagnoses and potential reductions in scarring.

SourceAmerican Chemical Society·JournalJournal of Proteome Research·DateJan 17, 2019